DOI: 10.1073/pnas.78.3.1508. Presence of a highly repetitive and widely dispersed DNA sequence in the human genome.

Presence of a highly repetitive and widely dispersed DNA sequence in the human genome.

10.1073/pnas.78.3.1508

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

A genomic DNA library consisting of human DNA fragments about 18 kilobases long cloned in a bacteriophage lambda vector was found to contain a specific repeated DNA segment. The repeated sequence is present in greater than 95% of the genomic library, and selected clones contain at least two copies of the sequence. Our experiments indicate that this highly repetitive sequence (approximately 400,000 copies per haploid genome) is widely distributed in the human genome and is represented in the cytoplasmic polysomal mRNA. This sequence is homologous to the 300-base-pair Alu repeat family, the predominant repeat sequence in man.

Bibliography

Tashima, M., Calabretta, B., Torelli, G., Scofield, M., Maizel, A., & Saunders, G. F. (1981). Presence of a highly repetitive and widely dispersed DNA sequence in the human genome. Proceedings of the National Academy of Sciences, 78(3), 1508â1512.

Authors 6

M Tashima (first)
B Calabretta (additional)
G Torelli (additional)
M Scofield (additional)
A Maizel (additional)
G F Saunders (additional)

References 0 Referenced 29

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 4:38 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 11:32 a.m.)
Indexed	1 year, 9 months ago (Nov. 23, 2023, 8:42 a.m.)
Issued	44 years, 5 months ago (March 1, 1981)
Published	44 years, 5 months ago (March 1, 1981)
Published Online	44 years, 5 months ago (March 1, 1981)
Published Print	44 years, 5 months ago (March 1, 1981)

Funders 0

None

BibTeX

@article{Tashima_1981, title={Presence of a highly repetitive and widely dispersed DNA sequence in the human genome.}, volume={78}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.78.3.1508}, DOI={10.1073/pnas.78.3.1508}, number={3}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Tashima, M and Calabretta, B and Torelli, G and Scofield, M and Maizel, A and Saunders, G F}, year={1981}, month=mar, pages={1508–1512} }

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