DOI: 10.1073/pnas.77.5.2429. Multiple methylation in processing of sensory signals during bacterial chemotaxis.

Multiple methylation in processing of sensory signals during bacterial chemotaxis.

10.1073/pnas.77.5.2429

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

The multiple banding pattern on NaDodSO4/polyacrylamide electrophoresis of a subset of the signal transduction proteins involved in bacterial chemotaxis has been shown to be caused by multiple methylation of a single gene product. At least four methyl groups are introduced per molecule of the sensing membrane protein to give a total of five bands. The separation of the bands appears to correspond to a Mr difference of 1500, probably caused by the binding of different amounts of DodSO4 molecules as carboxyl groups are modified. Multiple methylation, similar to multiple phosphorylation in other systems, appears to offer advantages in control and sensory processing.

Authors 2

A L DeFranco (first)
D E Koshland (additional)

References 0 Referenced 74

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 4:13 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 11:31 a.m.)
Indexed	1 month, 1 week ago (July 16, 2025, 9:23 a.m.)
Issued	45 years, 3 months ago (May 1, 1980)
Published	45 years, 3 months ago (May 1, 1980)
Published Online	45 years, 3 months ago (May 1, 1980)
Published Print	45 years, 3 months ago (May 1, 1980)

Funders 0

None

BibTeX

@article{DeFranco_1980, title={Multiple methylation in processing of sensory signals during bacterial chemotaxis.}, volume={77}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.77.5.2429}, DOI={10.1073/pnas.77.5.2429}, number={5}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={DeFranco, A L and Koshland, D E}, year={1980}, month=may, pages={2429–2433} }

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