DOI: 10.1073/pnas.76.10.5066. On the origin of the contractile force in skeletal muscle.

On the origin of the contractile force in skeletal muscle.

10.1073/pnas.76.10.5066

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Analysis of the early tension responses after abrupt step changes in the length of isometrically contracting skeletal muscle shows that the magnitude of the recovery tension (T2) and the time dependence of this process at various step displacements give a good correlation with the behavior expected for a helix-coil transition in the subfragment-2 (S-2) region of myosin. The "instantaneous" tension response (to T1) after the step change in length appears to have its origin in compliance within the coil region of S-2, which is formed through helix melting at the moment of force generation.

Bibliography

Harrington, W. F. (1979). On the origin of the contractile force in skeletal muscle. Proceedings of the National Academy of Sciences, 76(10), 5066â5070.

Authors 1

W F Harrington (first)

References 0 Referenced 69

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 3:51 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 10:51 a.m.)
Indexed	4 months, 2 weeks ago (April 4, 2025, 11:24 a.m.)
Issued	45 years, 10 months ago (Oct. 1, 1979)
Published	45 years, 10 months ago (Oct. 1, 1979)
Published Online	45 years, 10 months ago (Oct. 1, 1979)
Published Print	45 years, 10 months ago (Oct. 1, 1979)

Funders 0

None

BibTeX

@article{Harrington_1979, title={On the origin of the contractile force in skeletal muscle.}, volume={76}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.76.10.5066}, DOI={10.1073/pnas.76.10.5066}, number={10}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Harrington, W F}, year={1979}, month=oct, pages={5066–5070} }

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