DOI: 10.1073/pnas.74.7.2725. Distribution of 5-methylcytosine in chromatin.

Distribution of 5-methylcytosine in chromatin.

10.1073/pnas.74.7.2725

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

The content of 5-methylcytosine in eukaryotic DNA was measured by mass spectrometry. Almost equal amounts of methylated cytosine were found in the DNA of various tissues of the chicken. When chromatin or nuclei were digested with micrococcal nuclease, 50% of the DNA was found to be nuclease resistant. In contrast to this, over 75% of the 5-methylcytosine was protected from nuclease digestion by chromatin proteins. These results suggest that 5-methylcytosine is nonrandomly distributed with respect to the nucleoproteins.

Bibliography

Razin, A., & Cedar, H. (1977). Distribution of 5-methylcytosine in chromatin. Proceedings of the National Academy of Sciences, 74(7), 2725â2728.

Authors 2

A Razin (first)
H Cedar (additional)

References 0 Referenced 138

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 3:33 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 11:14 a.m.)
Indexed	1 month, 1 week ago (July 28, 2025, 5:24 p.m.)
Issued	48 years, 2 months ago (July 1, 1977)
Published	48 years, 2 months ago (July 1, 1977)
Published Online	48 years, 2 months ago (July 1, 1977)
Published Print	48 years, 2 months ago (July 1, 1977)

Funders 0

None

BibTeX

@article{Razin_1977, title={Distribution of 5-methylcytosine in chromatin.}, volume={74}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.74.7.2725}, DOI={10.1073/pnas.74.7.2725}, number={7}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Razin, A and Cedar, H}, year={1977}, month=jul, pages={2725–2728} }

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