DOI: 10.1073/pnas.74.3.864. Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.

Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.

10.1073/pnas.74.3.864

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Chromosomal protein A24 has a unique structure inasmuch as it contains histone 2A and a nonhistone polypeptide the sequence of which has been partially determined. Comparative analysis of the ninhydrin-insensitive amino-terminal tryptic peptides of protein A24 and histone 2A and a quantitative analysis of their carboxyl-terminal amino acid indicated that protein A24 has two amino termini and one carboxyl terminus. The amino acid sequence analysis of tryptic peptide 17' of protein A24: (see text) showed it contains tryptic peptide 17 of histone 2A, Lys-Thr-Glu-Ser-His-His-Lys. Lysine 119, the amino terminus of this peptide, which is derived from the histone 2A portion of protein A24, is linked by an isopeptide bond to the carboxyl group of a glycine residue. Accordingly, the branched structure of protein A24 proposed is: (see text).

Bibliography

Goldknopf, I. L., & Busch, H. (1977). Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24. Proceedings of the National Academy of Sciences, 74(3), 864â868.

Authors 2

I L Goldknopf (first)
H Busch (additional)

References 0 Referenced 309

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 3:28 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 10:51 a.m.)
Indexed	4 weeks, 2 days ago (July 25, 2025, 6:25 a.m.)
Issued	48 years, 5 months ago (March 1, 1977)
Published	48 years, 5 months ago (March 1, 1977)
Published Online	48 years, 5 months ago (March 1, 1977)
Published Print	48 years, 5 months ago (March 1, 1977)

Funders 0

None

BibTeX

@article{Goldknopf_1977, title={Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.}, volume={74}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.74.3.864}, DOI={10.1073/pnas.74.3.864}, number={3}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Goldknopf, I L and Busch, H}, year={1977}, month=mar, pages={864–868} }

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