DOI: 10.1073/pnas.73.8.2619. Handedness of crossover connections in beta sheets.

Handedness of crossover connections in beta sheets.

10.1073/pnas.73.8.2619

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

In a crossover connection, the polypeptide chain leaves one end of a beta sheet, forms a loop of any length and any conformation, and reenters the same beta sheet from the opposite end. Of the 85 examples of crossover connections which occur in the known protein structures, 83 are righthanded and only two are lefthanded. It is proposed that consistent handedness, even in long irregular loops, could be produced by the preferred twist direction of extended chain and the righthandedness of alpha-helices, provided certain conditions hold during the protein folding process.

Bibliography

Richardson, J. S. (1976). Handedness of crossover connections in beta sheets. Proceedings of the National Academy of Sciences, 73(8), 2619â2623.

Authors 1

J S Richardson (first)

References 0 Referenced 140

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 3:20 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 11:02 a.m.)
Indexed	4 weeks ago (July 30, 2025, 11:18 a.m.)
Issued	49 years ago (Aug. 1, 1976)
Published	49 years ago (Aug. 1, 1976)
Published Online	49 years ago (Aug. 1, 1976)
Published Print	49 years ago (Aug. 1, 1976)

Funders 0

None

BibTeX

@article{Richardson_1976, title={Handedness of crossover connections in beta sheets.}, volume={73}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.73.8.2619}, DOI={10.1073/pnas.73.8.2619}, number={8}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Richardson, J S}, year={1976}, month=aug, pages={2619–2623} }

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