Crossref journal-article
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences (341)
Abstract

A mutant unable to fuse nuclei during mating has been isolated from standard wild-type Saccharomyces cerevisiae. Tetrad analysis of the mutation responsible for this defect (kar1-1) shows that it segregates as a single Mendelian factor. The defect kn kaf1-1 appears to be nuclear limited. Cytological and genetic evidence shows that in this mutant the events associated with zygote formation are normal until the point of nuclear fusion. The consequence of this defect is the formation of a multinucleate zygote which in subsequent divisions can segregate heterokaryons and haploid heterplasmons.

Bibliography

Conde, J., & Fink, G. R. (1976). A mutant of Saccharomyces cerevisiae defective for nuclear fusion. Proceedings of the National Academy of Sciences, 73(10), 3651–3655.

Authors 2
  1. J Conde (first)
  2. G R Fink (additional)
References 0 Referenced 379

None

Dates
Type When
Created 19 years, 2 months ago (May 31, 2006, 3:12 a.m.)
Deposited 3 years, 4 months ago (April 13, 2022, 11:13 a.m.)
Indexed 3 weeks, 6 days ago (July 25, 2025, 5:59 a.m.)
Issued 48 years, 10 months ago (Oct. 1, 1976)
Published 48 years, 10 months ago (Oct. 1, 1976)
Published Online 48 years, 10 months ago (Oct. 1, 1976)
Published Print 48 years, 10 months ago (Oct. 1, 1976)
Funders 0

None

@article{Conde_1976, title={A mutant of Saccharomyces cerevisiae defective for nuclear fusion.}, volume={73}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.73.10.3651}, DOI={10.1073/pnas.73.10.3651}, number={10}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Conde, J and Fink, G R}, year={1976}, month=oct, pages={3651–3655} }