DOI: 10.1073/pnas.72.7.2691. Chromatin architecture: investigation of a subunit of chromatin by dark field electron microscopy.

Chromatin architecture: investigation of a subunit of chromatin by dark field electron microscopy.

10.1073/pnas.72.7.2691

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Dark field scanning electron microscopy of unstained, unfixed samples of chromatin, histone-1-depleted chromatin, and nucleohistone has been used to identify an apparent subunit of chromatin, namely a disk-shaped structure we term the unit particle, which is probably about 135 A wide and 50 A thick in the hydrated state. The unit particles are found at rather uniform intervals along thin DNA-like fibers. Histone 1 depletion leads to a bimodal distribution of these spacings. Our observations suggest that the unit particle consists of a loop of nucleoprotein, perhaps around a histone core.

Bibliography

Langmore, J. P., & Wooley, J. C. (1975). Chromatin architecture: investigation of a subunit of chromatin by dark field electron microscopy. Proceedings of the National Academy of Sciences, 72(7), 2691â2695.

Authors 2

J P Langmore (first)
J C Wooley (additional)

References 0 Referenced 51

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 3:09 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 11:03 a.m.)
Indexed	1 year, 2 months ago (June 21, 2024, 5:24 a.m.)
Issued	50 years, 2 months ago (July 1, 1975)
Published	50 years, 2 months ago (July 1, 1975)
Published Online	50 years, 2 months ago (July 1, 1975)
Published Print	50 years, 2 months ago (July 1, 1975)

Funders 0

None

BibTeX

@article{Langmore_1975, title={Chromatin architecture: investigation of a subunit of chromatin by dark field electron microscopy.}, volume={72}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.72.7.2691}, DOI={10.1073/pnas.72.7.2691}, number={7}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Langmore, J P and Wooley, J C}, year={1975}, month=jul, pages={2691–2695} }

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