Abstract
A protein methylation reaction involved in chemotaxis of Escherichia coli has been identified. The involvement of this reaction in chemotaxis in indicated by four lines of evidence. (a) The methylation reaction is altered in several classes of generally nonchemotactic mutants and is coreverted with the chemotaxis defects. (b) The methylation level of the protein is affected by chemotactic stimuli. (c) The transferred methyl group is derived from methionine and is labile, in accord with the known fact that chemotaxis requires a continuous supply of methionine. (d) Methylation is abnormal in various mutants having defective or missing flagella.
Dates
Type | When |
---|---|
Created | 19 years, 3 months ago (May 31, 2006, 3:02 a.m.) |
Deposited | 3 years, 4 months ago (April 13, 2022, 10:24 a.m.) |
Indexed | 3 months, 2 weeks ago (May 17, 2025, 7:25 a.m.) |
Issued | 49 years, 11 months ago (Oct. 1, 1975) |
Published | 49 years, 11 months ago (Oct. 1, 1975) |
Published Online | 49 years, 11 months ago (Oct. 1, 1975) |
Published Print | 49 years, 11 months ago (Oct. 1, 1975) |
@article{Kort_1975, title={Methylation of a membrane protein involved in bacterial chemotaxis.}, volume={72}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.72.10.3939}, DOI={10.1073/pnas.72.10.3939}, number={10}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Kort, E N and Goy, M F and Larsen, S H and Adler, J}, year={1975}, month=oct, pages={3939–3943} }