Abstract
Three exceptional cell lines have been tested for the presence of the Epstein-Barr virus genome by nucleic acid hybridization (complementary RNA·DNA) and Epstein-Barr virus-determined nuclear antigen tests. Two lines were derived from Swedish lymphoma cases and one from an African Burkitt-like lymphoma biopsy that was negative for Epstein-Barr virus DNA and the virus-determined nuclear antigen. All three lines apparently lacked the viral genome. Two of the three lines clearly had characteristics of B-cells (bone-marrow-derived).
Bibliography
Klein, G., Lindahl, T., Jondal, M., Leibold, W., Menézes, J., Nilsson, K., & Sundström, C. (1974). Continuous Lymphoid Cell Lines with Characteristics of B Cells (Bone-Marrow-Derived), Lacking the Epstein-Barr Virus Genome and Derived from Three Human Lymphomas. Proceedings of the National Academy of Sciences, 71(8), 3283â3286.
Dates
Type | When |
---|---|
Created | 19 years, 3 months ago (May 31, 2006, 2:59 a.m.) |
Deposited | 3 years, 4 months ago (April 13, 2022, 10:22 a.m.) |
Indexed | 3 months, 3 weeks ago (May 9, 2025, 1:50 a.m.) |
Issued | 51 years, 1 month ago (Aug. 1, 1974) |
Published | 51 years, 1 month ago (Aug. 1, 1974) |
Published Online | 51 years, 1 month ago (Aug. 1, 1974) |
Published Print | 51 years, 1 month ago (Aug. 1, 1974) |
@article{Klein_1974, title={Continuous Lymphoid Cell Lines with Characteristics of B Cells (Bone-Marrow-Derived), Lacking the Epstein-Barr Virus Genome and Derived from Three Human Lymphomas}, volume={71}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.71.8.3283}, DOI={10.1073/pnas.71.8.3283}, number={8}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Klein, George and Lindahl, Tomas and Jondal, Mikael and Leibold, Wolfgang and Menézes, José and Nilsson, Kenneth and Sundström, Christer}, year={1974}, month=aug, pages={3283–3286} }