DOI: 10.1073/pnas.71.5.1672. X-Ray Diffraction Studies of Nucleohistone: A Polyhelical Model of Chromosome Organization

X-Ray Diffraction Studies of Nucleohistone: A Polyhelical Model of Chromosome Organization

10.1073/pnas.71.5.1672

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

The possibility that nucleohistone is constituted by a helical arrangement of DNA molecules is analyzed in this paper. A polyhelical model of nucleohistone in plectanemic double coils of variable dimensions is found to be compatible with the x-ray diffraction results obtained in this and other laboratories. The radius of the coils varies between 35 and 45 Å, whereas the pitch varies between 200 and 120 Å. Another part of nucleohistone is much less coiled and contributes to the “background” scattering of the sample. This model is compatible with a lampbrush organization of the chromosome.

Bibliography

Subirana, J. A., & Puigjaner, L. C. (1974). X-Ray Diffraction Studies of Nucleohistone: A Polyhelical Model of Chromosome Organization. Proceedings of the National Academy of Sciences, 71(5), 1672â1676.

Authors 2

Juan A. Subirana (first)
Luis C. Puigjaner (additional)

References 0 Referenced 7

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 2:55 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 10:25 a.m.)
Indexed	1 year, 11 months ago (Sept. 13, 2023, 1:30 p.m.)
Issued	51 years, 4 months ago (May 1, 1974)
Published	51 years, 4 months ago (May 1, 1974)
Published Online	51 years, 4 months ago (May 1, 1974)
Published Print	51 years, 4 months ago (May 1, 1974)

Funders 0

None

BibTeX

@article{Subirana_1974, title={X-Ray Diffraction Studies of Nucleohistone: A Polyhelical Model of Chromosome Organization}, volume={71}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.71.5.1672}, DOI={10.1073/pnas.71.5.1672}, number={5}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Subirana, Juan A. and Puigjaner, Luis C.}, year={1974}, month=may, pages={1672–1676} }

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