DOI: 10.1073/pnas.70.8.2335. Nucleotide Sequences from Tryptophan Messenger RNA of <i>Escherichia coli</i> : The Sequence Corresponding to the Amino-Terminal Region of the First Polypeptide Specified by the Operon

Nucleotide Sequences from Tryptophan Messenger RNA of Escherichia coli : The Sequence Corresponding to the Amino-Terminal Region of the First Polypeptide Specified by the Operon

10.1073/pnas.70.8.2335

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Mutants with internal deletions that terminate near the operator end of the tryptophan operon of E. coli were used in studies on the nucleotide sequence at the 5′ end of the messenger RNA transcribed on this operon. The findings obtained permitted identification of a sequence of 43 nucleotides corresponding to the aminoterminal 11 amino acids of anthranilate synthetase component I, the polypeptide specified by the operator-proximal structural gene of the operon. It was also shown that the translation initiation codon for this polypeptide is preceded on the messenger by a “leader” sequence of unknown function, at least 150 nucleotides in length.

Bibliography

Bronson, M. J., Squires, C., & Yanofsky, C. (1973). Nucleotide Sequences from Tryptophan Messenger RNA of Escherichia coli â¯: The Sequence Corresponding to the Amino-Terminal Region of the First Polypeptide Specified by the Operon. Proceedings of the National Academy of Sciences, 70(8), 2335â2339.

Authors 3

Morley J. Bronson (first)
Craig Squires (additional)
Charles Yanofsky (additional)

References 0 Referenced 33

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 2:42 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 10:22 a.m.)
Indexed	1 year, 7 months ago (Jan. 9, 2024, 10:03 p.m.)
Issued	52 years, 1 month ago (Aug. 1, 1973)
Published	52 years, 1 month ago (Aug. 1, 1973)
Published Online	52 years, 1 month ago (Aug. 1, 1973)
Published Print	52 years, 1 month ago (Aug. 1, 1973)

Funders 0

None

BibTeX

@article{Bronson_1973, title={Nucleotide Sequences from Tryptophan Messenger RNA of Escherichia coli  : The Sequence Corresponding to the Amino-Terminal Region of the First Polypeptide Specified by the Operon}, volume={70}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.70.8.2335}, DOI={10.1073/pnas.70.8.2335}, number={8}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Bronson, Morley J. and Squires, Craig and Yanofsky, Charles}, year={1973}, month=aug, pages={2335–2339} }

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