DOI: 10.1073/pnas.70.3.934. An RNA that Multiplies Indefinitely with DNA-Dependent RNA Polymerase: Selection from a Random Copolymer

An RNA that Multiplies Indefinitely with DNA-Dependent RNA Polymerase: Selection from a Random Copolymer

10.1073/pnas.70.3.934

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

We have selected from a mixture of random polynucleotides an RNA that is able to replicate in the presence of the DNA-dependent RNA polymerase of Escherichia coli , provided the medium contains Mn 2+ and ITP, in addition to ATP, CTP, and UTP. The RNA consists of a chain of about 125 (±25) nucleotides and appears to have a defined, nonrepetitive sequence.

Bibliography

Biebricher, C. K., & Orgel, L. E. (1973). An RNA that Multiplies Indefinitely with DNA-Dependent RNA Polymerase: Selection from a Random Copolymer. Proceedings of the National Academy of Sciences, 70(3), 934â938.

Authors 2

Christof K. Biebricher (first)
Leslie E. Orgel (additional)

References 0 Referenced 37

None

Dates

Type	When
Created	19 years, 2 months ago (May 31, 2006, 2:42 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 10:40 a.m.)
Indexed	1 year, 7 months ago (Jan. 15, 2024, 7:58 p.m.)
Issued	52 years, 5 months ago (March 1, 1973)
Published	52 years, 5 months ago (March 1, 1973)
Published Online	52 years, 5 months ago (March 1, 1973)
Published Print	52 years, 5 months ago (March 1, 1973)

Funders 0

None

BibTeX

@article{Biebricher_1973, title={An RNA that Multiplies Indefinitely with DNA-Dependent RNA Polymerase: Selection from a Random Copolymer}, volume={70}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.70.3.934}, DOI={10.1073/pnas.70.3.934}, number={3}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Biebricher, Christof K. and Orgel, Leslie E.}, year={1973}, month=mar, pages={934–938} }

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