Abstract
We have found that vinblastine sulfate can precipitate a number of proteins in addition to microtubule protein. Those proteins which precipitate with vinblastine sulfate, all of which were derived from structure, also precipitate with Ca 2+ ions. Our results suggest that vinblastine sulfate, presumably acting as a cation, precipitates proteins by combining with sites which can also combine with Ca 2+ ions.
Dates
Type | When |
---|---|
Created | 19 years, 2 months ago (May 31, 2006, 2:21 a.m.) |
Deposited | 3 years, 4 months ago (April 13, 2022, 10:20 a.m.) |
Indexed | 1 year, 8 months ago (Nov. 23, 2023, 1:18 p.m.) |
Issued | 55 years, 1 month ago (July 1, 1970) |
Published | 55 years, 1 month ago (July 1, 1970) |
Published Online | 55 years, 1 month ago (July 1, 1970) |
Published Print | 55 years, 1 month ago (July 1, 1970) |
@article{Wilson_1970, title={Precipitation of Proteins by Vinblastine and Calcium Ions}, volume={66}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.66.3.807}, DOI={10.1073/pnas.66.3.807}, number={3}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Wilson, L. and Bryan, J. and Ruby, A. and Mazia, D.}, year={1970}, month=jul, pages={807–814} }