DOI: 10.1073/pnas.65.2.430. Peptide Chain Termination, VI. Purification and Site of Action of <i>S</i>

Peptide Chain Termination, VI. Purification and Site of Action of S

10.1073/pnas.65.2.430

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Peptide chain termination is a result of at least two events: terminator codon recognition and hydrolysis of peptidyl tRNA. A protein factor S , isolated from the supernatant of Escherichia coli B, stimulates fMet release. Factor S lowers the K m for terminator trinucleotides without altering the V max of release and therefore acts at terminator codon recognition. The S protein differs from initiation factors, elongation factor G , several forms of elongation factor T and release factors. The importance of the 2% Tu content in purified S is unresolved.

Bibliography

Goldstein, J., Milman, G., Scolnick, E., & Caskey, T. (1970). Peptide Chain Termination, VI. Purification and Site of Action of S. Proceedings of the National Academy of Sciences, 65(2), 430â437.

Authors 4

J. Goldstein (first)
G. Milman (additional)
E. Scolnick (additional)
T. Caskey (additional)

References 0 Referenced 21

None

Dates

Type	When
Created	19 years, 3 months ago (May 31, 2006, 2:18 a.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 10:39 a.m.)
Indexed	1 month, 4 weeks ago (July 2, 2025, 2:46 p.m.)
Issued	55 years, 7 months ago (Feb. 1, 1970)
Published	55 years, 7 months ago (Feb. 1, 1970)
Published Online	55 years, 7 months ago (Feb. 1, 1970)
Published Print	55 years, 7 months ago (Feb. 1, 1970)

Funders 0

None

BibTeX

@article{Goldstein_1970, title={Peptide Chain Termination, VI. Purification and Site of Action of S}, volume={65}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.65.2.430}, DOI={10.1073/pnas.65.2.430}, number={2}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Goldstein, J. and Milman, G. and Scolnick, E. and Caskey, T.}, year={1970}, month=feb, pages={430–437} }

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