Abstract
The free and membrane-bound ribosomes of hepatic cells were isolated and used to program protein synthesis in cell-free extracts. Immuno-electrophoretic and radioautographic analysis of the products showed that the membrane-bound ribosomes synthesized serum proteins, whereas ribosomes free of endoplasmic reticulum synthesized specific nonserum liver proteins. After synthesis, the serum proteins remained associated with membrane vesicles, whereas the other liver proteins were found free of cytoplasmic organelles.
Dates
Type | When |
---|---|
Created | 19 years, 3 months ago (May 31, 2006, 2:14 a.m.) |
Deposited | 3 years, 4 months ago (April 13, 2022, 10:15 a.m.) |
Indexed | 1 year, 7 months ago (Jan. 14, 2024, 5:42 p.m.) |
Issued | 56 years, 1 month ago (Aug. 1, 1969) |
Published | 56 years, 1 month ago (Aug. 1, 1969) |
Published Online | 56 years, 1 month ago (Aug. 1, 1969) |
Published Print | 56 years, 1 month ago (Aug. 1, 1969) |
@article{Ganoza_1969, title={In vitro SYNTHESIS OF DIFFERENT CATEGORIES OF SPECIFIC PROTEIN BY MEMBRANE-BOUND AND FREE RIBOSOMES}, volume={63}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.63.4.1370}, DOI={10.1073/pnas.63.4.1370}, number={4}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Ganoza, M. Clelia and Williams, Curtis A.}, year={1969}, month=aug, pages={1370–1376} }