DOI: 10.1073/pnas.97.7.3771. Understanding hippocampal activity by using purposeful behavior: Place navigation induces place cell discharge in both task-relevant and task-irrelevant spatial reference frames

Understanding hippocampal activity by using purposeful behavior: Place navigation induces place cell discharge in both task-relevant and task-irrelevant spatial reference frames

10.1073/pnas.97.7.3771

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Continuous rotation of an arena in a cue-rich room dissociates the stationary room-bound information from the rotating arena-bound information. This disrupted spatial discharge in the majority of place cells from rats trained to collect randomly scattered food. In contrast, most place cell firing patterns recorded from rats trained to solve a navigation task on the rotating arena were preserved during the rotation. Spatial discharge was preserved in both the task-relevant stationary and the task-irrelevant rotating reference frames, but firing was more organized in the task-relevant frame. It is concluded that, ( i ) the effects of environmental manipulations can be understood with confidence only when the rat's purposeful behavior is used to formulate interpretations of the data, and ( ii ) hippocampal place cell activity is organized in multiple overlapping spatial reference frames.

Bibliography

Zinyuk, L., Kubik, S., Kaminsky, Yu., Fenton, A. A., & Bures, J. (2000). Understanding hippocampal activity by using purposeful behavior: Place navigation induces place cell discharge in both task-relevant and task-irrelevant spatial reference frames. Proceedings of the National Academy of Sciences, 97(7), 3771â3776.

Authors 5

L. Zinyuk (first)
S. Kubik (additional)
Yu. Kaminsky (additional)
A. A. Fenton (additional)
J. Bures (additional)

References 40 Referenced 61

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Dates

Type	When
Created	13 years, 1 month ago (July 25, 2012, 1:37 p.m.)
Deposited	3 years, 4 months ago (April 13, 2022, 5:25 p.m.)
Indexed	4 months, 3 weeks ago (April 12, 2025, 7:32 p.m.)
Issued	25 years, 5 months ago (March 14, 2000)
Published	25 years, 5 months ago (March 14, 2000)
Published Online	25 years, 5 months ago (March 14, 2000)
Published Print	25 years, 5 months ago (March 28, 2000)

Funders 0

None

BibTeX

@article{Zinyuk_2000, title={Understanding hippocampal activity by using purposeful behavior: Place navigation induces place cell discharge in both task-relevant and task-irrelevant spatial reference frames}, volume={97}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.97.7.3771}, DOI={10.1073/pnas.97.7.3771}, number={7}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Zinyuk, L. and Kubik, S. and Kaminsky, Yu. and Fenton, A. A. and Bures, J.}, year={2000}, month=mar, pages={3771–3776} }

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