DOI: 10.1073/pnas.0437938100. Communication between neocortex and hippocampus during sleep in rodents

Communication between neocortex and hippocampus during sleep in rodents

10.1073/pnas.0437938100

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Both neocortical and hippocampal networks organize the firing patterns of their neurons by prominent oscillations during sleep, but the functional role of these rhythms is not well understood. Here, we show a robust correlation of neuronal discharges between the somatosensory cortex and hippocampus on both slow and fine time scales in the mouse and rat. Neuronal bursts in deep cortical layers, associated with sleep spindles and delta waves/slow rhythm, effectively triggered hippocampal discharges related to fast (ripple) oscillations. We hypothesize that oscillation-mediated temporal links coordinate specific information transfer between neocortical and hippocampal cell assemblies. Such a neocortical–hippocampal interplay may be important for memory consolidation.

Bibliography

Sirota, A., Csicsvari, J., Buhl, D., & BuzsÃ¡ki, G. (2003). Communication between neocortex and hippocampus during sleep in rodents. Proceedings of the National Academy of Sciences, 100(4), 2065â2069.

Authors 4

Anton Sirota (first)
Jozsef Csicsvari (additional)
Derek Buhl (additional)
György Buzsáki (additional)

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Dates

Type	When
Created	22 years, 6 months ago (Feb. 18, 2003, 3:04 p.m.)
Deposited	3 years, 4 months ago (April 12, 2022, 2:20 p.m.)
Indexed	2 days, 11 hours ago (Aug. 28, 2025, 8:10 a.m.)
Issued	22 years, 6 months ago (Feb. 7, 2003)
Published	22 years, 6 months ago (Feb. 7, 2003)
Published Online	22 years, 6 months ago (Feb. 7, 2003)
Published Print	22 years, 6 months ago (Feb. 18, 2003)

Funders 0

None

BibTeX

@article{Sirota_2003, title={Communication between neocortex and hippocampus during sleep in rodents}, volume={100}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.0437938100}, DOI={10.1073/pnas.0437938100}, number={4}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Sirota, Anton and Csicsvari, Jozsef and Buhl, Derek and Buzsáki, György}, year={2003}, month=feb, pages={2065–2069} }

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