DOI: 10.1073/pnas.040556497. <i>Notch</i> signaling and the determination of appendage identity

Notch signaling and the determination of appendage identity

10.1073/pnas.040556497

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

The Notch signaling pathway defines an evolutionarily conserved cell–cell interaction mechanism that throughout development controls the ability of precursor cells to respond to developmental signals. Here we show that Notch signaling regulates the expression of the master control genes eyeless , vestigial , and Distal-less , which in combination with homeotic genes induce the formation of eyes, wings, antennae, and legs. Therefore, Notch is involved in a common regulatory pathway for the determination of the various Drosophila appendages.

Bibliography

Kurata, S., Go, M. J., Artavanis-Tsakonas, S., & Gehring, W. J. (2000). Notch signaling and the determination of appendage identity. Proceedings of the National Academy of Sciences, 97(5), 2117â2122.

Authors 4

Shoichiro Kurata (first)
Masahiro J. Go (additional)
Spyros Artavanis-Tsakonas (additional)
Walter J. Gehring (additional)

References 42 Referenced 100

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Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 10:32 a.m.)
Deposited	3 years, 4 months ago (April 12, 2022, 8:53 a.m.)
Indexed	1 year ago (Aug. 27, 2024, 12:35 p.m.)
Issued	25 years, 6 months ago (Feb. 11, 2000)
Published	25 years, 6 months ago (Feb. 11, 2000)
Published Online	25 years, 6 months ago (Feb. 11, 2000)
Published Print	25 years, 6 months ago (Feb. 29, 2000)

Funders 0

None

BibTeX

@article{Kurata_2000, title={Notch signaling and the determination of appendage identity}, volume={97}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.040556497}, DOI={10.1073/pnas.040556497}, number={5}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Kurata, Shoichiro and Go, Masahiro J. and Artavanis-Tsakonas, Spyros and Gehring, Walter J.}, year={2000}, month=feb, pages={2117–2122} }

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