DOI: 10.1073/pnas.0307928100. Toward efficient asymmetric hydrogenation: Architectural and functional engineering of chiral molecular catalysts

Toward efficient asymmetric hydrogenation: Architectural and functional engineering of chiral molecular catalysts

10.1073/pnas.0307928100

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Asymmetric hydrogenation uses inexpensive, clean hydrogen gas and a very small amount of a chiral molecular catalyst, providing the most powerful way to produce a wide array of enantio-enriched compounds in a large quantity without forming any waste. The recent revolutionary advances in this field have entirely changed the synthetic approach to producing performance chemicals that require a high degree of structural precision. The means of developing efficient asymmetric hydrogenations is discussed from a mechanistic point of view.

Bibliography

Noyori, R., Kitamura, M., & Ohkuma, T. (2004). Toward efficient asymmetric hydrogenation: Architectural and functional engineering of chiral molecular catalysts. Proceedings of the National Academy of Sciences, 101(15), 5356â5362.

Authors 3

Ryoji Noyori (first)
Masato Kitamura (additional)
Takeshi Ohkuma (additional)

References 53 Referenced 260

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Ohkuma, T. & Noyori, R. (1999) in Comprehensive Asymmetric Catalysis, eds. Jacobsen, E. N., Pfaltz, A. & Yamamoto, H. (Springer, Berlin), Vol. 1, pp. 199–246. / Comprehensive Asymmetric Catalysis (1999)
Ohkuma T. Kitamura M. & Noyori R. (2000) in Catalytic Asymmetric Synthesis ed. Ojima I. (Wiley New York) 2nd Ed. pp. 1–110.
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Dates

Type	When
Created	21 years, 5 months ago (March 19, 2004, 8:13 p.m.)
Deposited	3 years, 4 months ago (April 12, 2022, 9:57 a.m.)
Indexed	1 month, 3 weeks ago (July 2, 2025, 11:39 a.m.)
Issued	21 years, 5 months ago (March 19, 2004)
Published	21 years, 5 months ago (March 19, 2004)
Published Online	21 years, 5 months ago (March 19, 2004)
Published Print	21 years, 4 months ago (April 13, 2004)

Funders 0

None

BibTeX

@article{Noyori_2004, title={Toward efficient asymmetric hydrogenation: Architectural and functional engineering of chiral molecular catalysts}, volume={101}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.0307928100}, DOI={10.1073/pnas.0307928100}, number={15}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Noyori, Ryoji and Kitamura, Masato and Ohkuma, Takeshi}, year={2004}, month=mar, pages={5356–5362} }

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