DOI: 10.1073/pnas.0136891100. A quantitative structure–function relationship for the Photosystem II reaction center: Supermolecular behavior in natural photosynthesis

A quantitative structure–function relationship for the Photosystem II reaction center: Supermolecular behavior in natural photosynthesis

10.1073/pnas.0136891100

Crossref journal-article

Proceedings of the National Academy of Sciences

Proceedings of the National Academy of Sciences (341)

Abstract

Light-induced charge separation is the primary photochemical event of photosynthesis. Efficient charge separation in photosynthetic reaction centers requires the balancing of electron and excitation energy transfer processes, and in Photosystem II (PSII), these processes are particularly closely entangled. Calculations that treat the cofactors of the PSII reaction center as a supermolecular complex allow energy and electron transfer reactions to be described in a unified way. This calculational approach is shown to be in good agreement with experimentally observed energy and electron transfer dynamics. This supermolecular view also correctly predicts the effect of changing the redox potentials of cofactors by site-directed mutagenesis, thus providing a unified and quantitative structure–function relationship for the PSII reaction center.

Bibliography

Barter, L. M. C., Durrant, J. R., & Klug, D. R. (2003). A quantitative structureâfunction relationship for the Photosystem II reaction center: Supermolecular behavior in natural photosynthesis. Proceedings of the National Academy of Sciences, 100(3), 946â951.

Authors 3

Laura M. C. Barter (first)
James R. Durrant (additional)
David R. Klug (additional)

References 34 Referenced 72

10.1146/annurev.arplant.47.1.655
10.1073/pnas.92.11.4798
10.1021/jp960388d
10.1016/0301-0104(95)00037-O
10.1021/jp953714i
10.1021/jp9906738
10.1073/pnas.95.11.6128
10.1021/jp9634058
10.1038/35055589
10.1073/pnas.141239598
10.1021/bi980502d
10.1074/jbc.271.4.2093
S Kwa Ph.D. thesis (Vrije Universiteit, Amsterdam), pp. 131 (1993). / Ph.D. thesis by Kwa S (1993)
10.1038/355796a0
10.1016/0022-5193(68)90073-8
J R Durrant, P J Nixon, J Barber, D R Klug XIth International Congress on Photosynthesis, ed G Garab (Kluwer, Dordrecht, The Netherlands) II, 1041–1044 (1998). / XIth International Congress on Photosynthesis by Durrant J R (1998)
S Kumazaki, D M Joseph, B Crystall, Y Tachibana, J Durrant, J Barber, G Porter, K Yoshihara, D R Klug Photosynthesis: From Light to Biosphere, ed P Mathis (Kluwer, Dordrecht, The Netherlands) 1, 883–886 (1995). (10.1007/978-94-009-0173-5_211) / Photosynthesis: From Light to Biosphere by Kumazaki S (1995)
10.1016/S0006-3495(94)80483-7
10.1021/j100064a026
10.1073/pnas.89.18.8517
10.1021/bi9607012
10.1021/jp962982t
10.1021/bi00148a027
10.1021/jp951984v
10.1039/a705648f
10.1021/jp990284d
10.1073/pnas.89.23.11632
10.1021/bi9703756
10.1038/43699
10.1016/0968-0004(92)90503-2
10.1021/bi001724q
10.1021/ja00487a079
10.1021/bi00253a015
10.1073/pnas.92.7.2929

Dates

Type	When
Created	22 years, 7 months ago (Feb. 4, 2003, 12:24 p.m.)
Deposited	3 years, 4 months ago (April 12, 2022, 9:17 a.m.)
Indexed	4 weeks, 2 days ago (Aug. 6, 2025, 8:59 a.m.)
Issued	22 years, 7 months ago (Jan. 21, 2003)
Published	22 years, 7 months ago (Jan. 21, 2003)
Published Online	22 years, 7 months ago (Jan. 21, 2003)
Published Print	22 years, 7 months ago (Feb. 4, 2003)

Funders 0

None

BibTeX

@article{Barter_2003, title={A quantitative structure–function relationship for the Photosystem II reaction center: Supermolecular behavior in natural photosynthesis}, volume={100}, ISSN={1091-6490}, url={http://dx.doi.org/10.1073/pnas.0136891100}, DOI={10.1073/pnas.0136891100}, number={3}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Barter, Laura M. C. and Durrant, James R. and Klug, David R.}, year={2003}, month=jan, pages={946–951} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        6
      ]
    ],
    "date-time": "2025-08-06T12:59:35Z",
    "timestamp": 1754485175717
  },
  "reference-count": 34,
  "publisher": "Proceedings of the National Academy of Sciences",
  "issue": "3",
  "content-domain": {
    "domain": [
      "www.pnas.org"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        2003,
        2,
        4
      ]
    ]
  },
  "abstract": "<jats:p>Light-induced charge separation is the primary photochemical event of photosynthesis. Efficient charge separation in photosynthetic reaction centers requires the balancing of electron and excitation energy transfer processes, and in Photosystem II (PSII), these processes are particularly closely entangled. Calculations that treat the cofactors of the PSII reaction center as a supermolecular complex allow energy and electron transfer reactions to be described in a unified way. This calculational approach is shown to be in good agreement with experimentally observed energy and electron transfer dynamics. This supermolecular view also correctly predicts the effect of changing the redox potentials of cofactors by site-directed mutagenesis, thus providing a unified and quantitative structure\u2013function relationship for the PSII reaction center.</jats:p>",
  "DOI": "10.1073/pnas.0136891100",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2003,
        2,
        4
      ]
    ],
    "date-time": "2003-02-04T17:24:41Z",
    "timestamp": 1044379481000
  },
  "page": "946-951",
  "update-policy": "http://dx.doi.org/10.1073/pnas.cm10313",
  "source": "Crossref",
  "is-referenced-by-count": 72,
  "title": "A quantitative structure\u2013function relationship for the Photosystem II reaction center: Supermolecular behavior in natural photosynthesis",
  "prefix": "10.1073",
  "volume": "100",
  "author": [
    {
      "given": "Laura M. C.",
      "family": "Barter",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Chemistry, Imperial College, London SW7 2AY, United Kingdom"
        }
      ]
    },
    {
      "given": "James R.",
      "family": "Durrant",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemistry, Imperial College, London SW7 2AY, United Kingdom"
        }
      ]
    },
    {
      "given": "David R.",
      "family": "Klug",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemistry, Imperial College, London SW7 2AY, United Kingdom"
        }
      ]
    }
  ],
  "member": "341",
  "published-online": {
    "date-parts": [
      [
        2003,
        1,
        21
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_3_3_1_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1146/annurev.arplant.47.1.655"
    },
    {
      "key": "e_1_3_3_2_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.92.11.4798"
    },
    {
      "key": "e_1_3_3_3_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/jp960388d"
    },
    {
      "key": "e_1_3_3_4_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0301-0104(95)00037-O"
    },
    {
      "key": "e_1_3_3_5_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/jp953714i"
    },
    {
      "key": "e_1_3_3_6_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/jp9906738"
    },
    {
      "key": "e_1_3_3_7_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.95.11.6128"
    },
    {
      "key": "e_1_3_3_8_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/jp9634058"
    },
    {
      "key": "e_1_3_3_9_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/35055589"
    },
    {
      "key": "e_1_3_3_10_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.141239598"
    },
    {
      "key": "e_1_3_3_11_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi980502d"
    },
    {
      "key": "e_1_3_3_12_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1074/jbc.271.4.2093"
    },
    {
      "key": "e_1_3_3_13_2",
      "first-page": "131",
      "volume-title": "Ph.D. thesis",
      "author": "Kwa S",
      "year": "1993",
      "unstructured": "S Kwa Ph.D. thesis (Vrije Universiteit, Amsterdam), pp. 131 (1993)."
    },
    {
      "key": "e_1_3_3_14_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/355796a0"
    },
    {
      "key": "e_1_3_3_15_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0022-5193(68)90073-8"
    },
    {
      "key": "e_1_3_3_16_2",
      "first-page": "1041",
      "volume-title": "XIth International Congress on Photosynthesis",
      "author": "Durrant J R",
      "year": "1998",
      "unstructured": "J R Durrant, P J Nixon, J Barber, D R Klug XIth International Congress on Photosynthesis, ed G Garab (Kluwer, Dordrecht, The Netherlands) II, 1041\u20131044 (1998)."
    },
    {
      "key": "e_1_3_3_17_2",
      "doi-asserted-by": "crossref",
      "first-page": "883",
      "DOI": "10.1007/978-94-009-0173-5_211",
      "volume-title": "Photosynthesis: From Light to Biosphere",
      "author": "Kumazaki S",
      "year": "1995",
      "unstructured": "S Kumazaki, D M Joseph, B Crystall, Y Tachibana, J Durrant, J Barber, G Porter, K Yoshihara, D R Klug Photosynthesis: From Light to Biosphere, ed P Mathis (Kluwer, Dordrecht, The Netherlands) 1, 883\u2013886 (1995)."
    },
    {
      "key": "e_1_3_3_18_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0006-3495(94)80483-7"
    },
    {
      "key": "e_1_3_3_19_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/j100064a026"
    },
    {
      "key": "e_1_3_3_20_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.89.18.8517"
    },
    {
      "key": "e_1_3_3_21_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi9607012"
    },
    {
      "key": "e_1_3_3_22_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/jp962982t"
    },
    {
      "key": "e_1_3_3_23_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00148a027"
    },
    {
      "key": "e_1_3_3_24_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/jp951984v"
    },
    {
      "key": "e_1_3_3_25_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1039/a705648f"
    },
    {
      "key": "e_1_3_3_26_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/jp990284d"
    },
    {
      "key": "e_1_3_3_27_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.89.23.11632"
    },
    {
      "key": "e_1_3_3_28_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi9703756"
    },
    {
      "key": "e_1_3_3_29_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/43699"
    },
    {
      "key": "e_1_3_3_30_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0968-0004(92)90503-2"
    },
    {
      "key": "e_1_3_3_31_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi001724q"
    },
    {
      "key": "e_1_3_3_32_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/ja00487a079"
    },
    {
      "key": "e_1_3_3_33_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00253a015"
    },
    {
      "key": "e_1_3_3_34_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.92.7.2929"
    }
  ],
  "container-title": "Proceedings of the National Academy of Sciences",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://pnas.org/doi/pdf/10.1073/pnas.0136891100",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2022,
        4,
        12
      ]
    ],
    "date-time": "2022-04-12T13:17:21Z",
    "timestamp": 1649769441000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://pnas.org/doi/full/10.1073/pnas.0136891100"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2003,
        1,
        21
      ]
    ]
  },
  "references-count": 34,
  "journal-issue": {
    "issue": "3",
    "published-print": {
      "date-parts": [
        [
          2003,
          2,
          4
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1073/pnas.0136891100"
  ],
  "URL": "http://dx.doi.org/10.1073/pnas.0136891100",
  "relation": {},
  "ISSN": [
    "0027-8424",
    "1091-6490"
  ],
  "subject": [],
  "container-title-short": "Proc. Natl. Acad. Sci. U.S.A.",
  "published": {
    "date-parts": [
      [
        2003,
        1,
        21
      ]
    ]
  },
  "assertion": [
    {
      "value": "2001-12-20",
      "order": 0,
      "name": "received",
      "label": "Received",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    },
    {
      "value": "2003-01-21",
      "order": 2,
      "name": "published",
      "label": "Published",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    }
  ]
}