Abstract
We describe a microfluidic system allowing fast and efficient size-dependent separation of droplets using hydrodynamics. This system allows efficient fractionation of droplets with a difference in volume as small as 2.33-fold (corresponding to a 1.33-fold difference in diameter of spherical droplets) at >4.5 kHz frequencies. To demonstrate the utility of the system we combined the size-fractionation module with a passive droplet fusion module to create an integrated microfluidic platform allowing the preparation of highly monodisperse emulsions composed of >99% pairwise fused droplets. This type of microfluidic platform should be useful for many droplet-based lab-on-a-chip applications.
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Dates
Type | When |
---|---|
Created | 15 years, 9 months ago (Nov. 19, 2009, 6:34 p.m.) |
Deposited | 2 years, 1 month ago (July 2, 2023, 12:56 p.m.) |
Indexed | 1 month ago (July 30, 2025, 6:53 a.m.) |
Issued | 15 years, 9 months ago (Nov. 16, 2009) |
Published | 15 years, 9 months ago (Nov. 16, 2009) |
Published Online | 15 years, 9 months ago (Nov. 18, 2009) |
Published Print | 15 years, 9 months ago (Nov. 16, 2009) |
@article{Mazutis_2009, title={Preparation of monodisperse emulsions by hydrodynamic size fractionation}, volume={95}, ISSN={1077-3118}, url={http://dx.doi.org/10.1063/1.3250432}, DOI={10.1063/1.3250432}, number={20}, journal={Applied Physics Letters}, publisher={AIP Publishing}, author={Mazutis, Linas and Griffiths, Andrew D.}, year={2009}, month=nov }