DOI: 10.1063/1.1419047. Green fluorescent proteins as optically controllable elements in bioelectronics

Green fluorescent proteins as optically controllable elements in bioelectronics

10.1063/1.1419047

Crossref journal-article

AIP Publishing

Applied Physics Letters (317)

Abstract

A single-biomolecule optical toggle switch is demonstrated based on a mutated green fluorescent protein (GFP). We have exploited molecular biology techniques to tailor the GFP molecular structure and photophysical properties and to give it optically controlled bistability between two distinct states. We present optical control of the fluorescence dynamics with two laser beams at 476 and 350 nm down to the ultimate limit of single molecules. These results indicate that GFP-class fluorophores are promising candidates for the realization of biomolecular devices such as volumetric optical memories and optical switches.

Bibliography

Cinelli, R. A. G., Pellegrini, V., Ferrari, A., Faraci, P., NifosÄ±Ì, R., Tyagi, M., Giacca, M., & Beltram, F. (2001). Green fluorescent proteins as optically controllable elements in bioelectronics. Applied Physics Letters, 79(20), 3353â3355.

Authors 8

Riccardo A. G. Cinelli (first)
Vittorio Pellegrini (additional)
Aldo Ferrari (additional)
Paolo Faraci (additional)
Riccardo Nifosı̀ (additional)
Mudit Tyagi (additional)
Mauro Giacca (additional)
Fabio Beltram (additional)

References 24 Referenced 54

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Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 8:42 a.m.)
Deposited	1 year, 6 months ago (Feb. 3, 2024, 4:08 p.m.)
Indexed	1 year, 5 months ago (March 4, 2024, 4:22 p.m.)
Issued	23 years, 9 months ago (Nov. 12, 2001)
Published	23 years, 9 months ago (Nov. 12, 2001)
Published Print	23 years, 9 months ago (Nov. 12, 2001)

Funders 0

None

BibTeX

@article{Cinelli_2001, title={Green fluorescent proteins as optically controllable elements in bioelectronics}, volume={79}, ISSN={1077-3118}, url={http://dx.doi.org/10.1063/1.1419047}, DOI={10.1063/1.1419047}, number={20}, journal={Applied Physics Letters}, publisher={AIP Publishing}, author={Cinelli, Riccardo A. G. and Pellegrini, Vittorio and Ferrari, Aldo and Faraci, Paolo and Nifosı̀, Riccardo and Tyagi, Mudit and Giacca, Mauro and Beltram, Fabio}, year={2001}, month=nov, pages={3353–3355} }

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