DOI: 10.1055/s-0038-1649681. A Parent-Twin Study of Plasma Levels of Histidine-Rich Glycoprotein (HRG)

A Parent-Twin Study of Plasma Levels of Histidine-Rich Glycoprotein (HRG)

10.1055/s-0038-1649681

Crossref journal-article

Georg Thieme Verlag KG

Thrombosis and Haemostasis (194)

Abstract

SummaryHistidine-rich glycoprotein (HRG) is a non-enzymatic glycoprotein that acts as a modulator of several plasma proteins involved in coagulation and fibrinolysis. The contributions of genetic and environmental influences to inter-individual variation in plasma levels of HRG were studied in 160 Dutch families consisting of adolescent twin pairs and their parents. Results showed that 69% of the variance in plasma HRG concentrations could be accounted for by genetic factors. Heritability was the same in males and females and in parents and their offspring. There was no association between HRG levels of husband and wife and no evidence was found for the influence of shared family environment on the resemblance between relatives.

Bibliography

Boomsma, D. I., Hennis, B. C., van Wees, A. G. M., Frants, R. R., & Kluft, C. (1993). A Parent-Twin Study of Plasma Levels of Histidine-Rich Glycoprotein (HRG). Thrombosis and Haemostasis, 70(05), 848â851.

Authors 5

D I Boomsma (additional)
B C Hennis (additional)
A G M van Wees (additional)
R R Frants (additional)
C Kluft (additional)

References 0 Referenced 15

None

Dates

Type	When
Created	7 years, 1 month ago (July 5, 2018, 2:31 p.m.)
Deposited	5 years, 8 months ago (Dec. 5, 2019, 7:41 a.m.)
Indexed	1 month ago (July 28, 2025, 2:40 a.m.)
Issued	32 years, 7 months ago (Jan. 1, 1993)
Published	32 years, 7 months ago (Jan. 1, 1993)
Published Online	7 years, 1 month ago (July 5, 2018)
Published Print	32 years, 7 months ago (Jan. 1, 1993)

Funders 0

None

BibTeX

@article{Boomsma_1993, title={A Parent-Twin Study of Plasma Levels of Histidine-Rich Glycoprotein (HRG)}, volume={70}, ISSN={2567-689X}, url={http://dx.doi.org/10.1055/s-0038-1649681}, DOI={10.1055/s-0038-1649681}, number={05}, journal={Thrombosis and Haemostasis}, publisher={Georg Thieme Verlag KG}, author={Boomsma, D I and Hennis, B C and van Wees, A G M and Frants, R R and Kluft, C}, year={1993}, pages={848–851} }

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