DOI: 10.1055/s-0037-1616229. Integrin Activation

Integrin Activation

10.1055/s-0037-1616229

Crossref journal-article

Georg Thieme Verlag KG

Thrombosis and Haemostasis (194)

Abstract

SummaryIntegrins are cell surface adhesion receptors that participate in a variety of important processes throughout the vasculature. Here we summarize some recent findings on the regulation of integrin mediated cellular adhesion. Particular emphasis is placed on the regulation of integrin affinity for ligand (activation), although this is just one mechanism by which regulation of integrin-dependent cell adhesion can occur. Also discussed are recent observations on the structural basis of integrin activation, the role of the cytoplasmic domain in integrin affinity regulation, and potential mechanisms by which activation signals are propagated from integrin cytoplasmic domains to the extracellular ligand binding domain.

Bibliography

Woodside, D. G., Liu, S., & Ginsberg, M. H. (2001). Integrin Activation. Thrombosis and Haemostasis, 86(07), 316â323.

Authors 3

D. G. Woodside (first)
S. Liu (first)
M. H. Ginsberg (additional)

References 0 Referenced 52

None

Dates

Type	When
Created	7 years, 5 months ago (March 20, 2018, 6:01 a.m.)
Deposited	7 years, 5 months ago (March 20, 2018, 6:02 a.m.)
Indexed	4 months, 2 weeks ago (April 8, 2025, 2:50 p.m.)
Issued	24 years, 7 months ago (Jan. 1, 2001)
Published	24 years, 7 months ago (Jan. 1, 2001)
Published Online	7 years, 8 months ago (Dec. 12, 2017)
Published Print	24 years, 7 months ago (Jan. 1, 2001)

Funders 1

American Heart Association 10.13039/100000968
Region: Americas
gov (Associations and societies (private and public))
Labels5
1. American Heart Association, Inc.
2. AMERICAN HEART ASSOC.
3. American Heart Assn
4. Association for the Prevention and Relief of Heart Disease
5. AHA

BibTeX

@article{Woodside_2001, title={Integrin Activation}, volume={86}, ISSN={2567-689X}, url={http://dx.doi.org/10.1055/s-0037-1616229}, DOI={10.1055/s-0037-1616229}, number={07}, journal={Thrombosis and Haemostasis}, publisher={Georg Thieme Verlag KG}, author={Woodside, D. G. and Liu, S. and Ginsberg, M. H.}, year={2001}, pages={316–323} }

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