DOI: 10.1046/j.1529-8027.2002.02002.x. Degeneration and regeneration of the peripheral nervous system: From Augustus Waller's observations to neuroinflammation

Degeneration and regeneration of the peripheral nervous system: From Augustus Waller's observations to neuroinflammation

10.1046/j.1529-8027.2002.02002.x

Crossref journal-article

Wiley

Journal of the Peripheral Nervous System (311)

Abstract

Abstract This review article on the degeneration and regeneration of peripheral nerve fibers was presented as a Plenary Lecture at the 2001 meeting of the Peripheral Nerve Society. It is accompanied by a reprint of Augustus Waller's 1850 article, which gave rise to the pathologic process termed Wallerian degeneration. This review is focused on the role of neuroinflammation in Wallerian degeneration and how immune mediators contribute to both axonal degeneration and regeneration. Similarities and differences between the PNS and CNS in terms of inflammation and microglial activation after nerve injury are discussed, and point towards progress in understanding the failure of nerve fiber regeneration in the CNS.

Bibliography

Stoll, G., Jander, S., & Myers, R. R. (2002). Degeneration and regeneration of the peripheral nervous system: From Augustus Wallerâs observations to neuroinflammation. Journal of the Peripheral Nervous System, 7(1), 13â27. Portico.

Authors 3

Guido Stoll (first)
Sebastian Jander (additional)
Robert R. Myers (additional)

References 55 Referenced 303

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Dates

Type	When
Created	22 years, 5 months ago (March 12, 2003, 2:18 a.m.)
Deposited	1 year, 11 months ago (Sept. 11, 2023, 7:27 a.m.)
Indexed	2 weeks ago (Aug. 21, 2025, 1:13 p.m.)
Issued	23 years, 6 months ago (March 1, 2002)
Published	23 years, 6 months ago (March 1, 2002)
Published Online	16 years, 11 months ago (Sept. 19, 2008)
Published Print	23 years, 6 months ago (March 1, 2002)

Funders 0

None

BibTeX

@article{Stoll_2002, title={Degeneration and regeneration of the peripheral nervous system: From Augustus Waller’s observations to neuroinflammation}, volume={7}, ISSN={1529-8027}, url={http://dx.doi.org/10.1046/j.1529-8027.2002.02002.x}, DOI={10.1046/j.1529-8027.2002.02002.x}, number={1}, journal={Journal of the Peripheral Nervous System}, publisher={Wiley}, author={Stoll, Guido and Jander, Sebastian and Myers, Robert R.}, year={2002}, month=mar, pages={13–27} }

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