DOI: 10.1042/cs0610627. Effect of Exercise on Protein Turnover in Man

Effect of Exercise on Protein Turnover in Man

10.1042/cs0610627

Crossref journal-article

Portland Press Ltd.

Clinical Science (288)

Abstract

1. We have investigated the effects of moderate long-term exercise on protein turnover in fed man by measuring the extent of whole-body nitrogen production, the labelling of urinary ammonia from ingested [15N]glycine and plasma, muscle and urine free amino acid concentrations. 2. Judged both from nitrogen production, and from the extent of 13CO2 production from ingested l-[l-13C]leucine, exercise causes a substantial rise in amino acid catabolism. 3. Amino acids catabolized during exercise appear to become available through a fall in whole-body protein synthesis and a rise in whole-body protein breakdown. After exercise, protein balance becomes positive through a rise in the rate of whole-body synthesis in excess of breakdown. 4. Studies of free 3-methylhistidine in muscle, plasma and urine samples suggest that exercise decreases the fractional rate of myofibrillar protein breakdown, in contrast with the apparent rise in whole-body breakdown.

Bibliography

Rennie, M. J., Edwards, R. H. T., Krywawych, S., Davies, C. T. M., Halliday, D., Waterlow, J. C., & Millward, D. J. (1981). Effect of Exercise on Protein Turnover in Man. Clinical Science, 61(5), 627â639.

Authors 7

M. J. Rennie (first)
R. H. T. Edwards (additional)
S. Krywawych (additional)
C. T. M. Davies (additional)
D. Halliday (additional)
J. C. Waterlow (additional)
D. J. Millward (additional)

References 0 Referenced 218

None

Dates

Type	When
Created	10 years ago (Aug. 7, 2015, 6:38 a.m.)
Deposited	3 years, 9 months ago (Dec. 2, 2021, 3:19 p.m.)
Indexed	1 month ago (Aug. 2, 2025, 1:18 a.m.)
Issued	43 years, 10 months ago (Nov. 1, 1981)
Published	43 years, 10 months ago (Nov. 1, 1981)
Published Print	43 years, 10 months ago (Nov. 1, 1981)

Funders 0

None

BibTeX

@article{Rennie_1981, title={Effect of Exercise on Protein Turnover in Man}, volume={61}, ISSN={1470-8736}, url={http://dx.doi.org/10.1042/cs0610627}, DOI={10.1042/cs0610627}, number={5}, journal={Clinical Science}, publisher={Portland Press Ltd.}, author={Rennie, M. J. and Edwards, R. H. T. and Krywawych, S. and Davies, C. T. M. and Halliday, D. and Waterlow, J. C. and Millward, D. J.}, year={1981}, month=nov, pages={627–639} }

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