DOI: 10.1042/bj3290209. Signal transduction by the Wnt family of ligands

Signal transduction by the Wnt family of ligands

10.1042/bj3290209

Crossref journal-article

Portland Press Ltd.

Biochemical Journal (288)

Abstract

The Wnt genes encode a large family of secreted polypeptides that mediate cell-cell communication in diverse developmental processes. The loss or inappropriate activation of Wnt expression has been shown to alter cell fate, morphogenesis and mitogenesis. Recent progress has identified Wnt receptors and components of an intracellular signalling pathway that mediate Wnt-dependent transcription. This review will highlight this ‘core’ Wnt signal-transduction pathway, but also aims to reveal the potential diversity of Wnt signalling targets. Particular attention will be paid to the overlap between developmental biology and oncogenesis, since recent progress shows Wnt signalling forms a paradigm for an interdisciplinary approach.

Bibliography

DALE, C. T. (1998). Signal transduction by the Wnt family of ligands. Biochemical Journal, 329(2), 209â223.

Authors 1

C. Trevor DALE (first)

References 0 Referenced 368

None

Dates

Type	When
Created	10 years ago (Aug. 10, 2015, 5:59 p.m.)
Deposited	3 years, 9 months ago (Nov. 23, 2021, 7:25 p.m.)
Indexed	1 week, 3 days ago (Aug. 21, 2025, 1:27 p.m.)
Issued	27 years, 7 months ago (Jan. 15, 1998)
Published	27 years, 7 months ago (Jan. 15, 1998)
Published Print	27 years, 7 months ago (Jan. 15, 1998)

Funders 0

None

BibTeX

@article{DALE_1998, title={Signal transduction by the Wnt family of ligands}, volume={329}, ISSN={1470-8728}, url={http://dx.doi.org/10.1042/bj3290209}, DOI={10.1042/bj3290209}, number={2}, journal={Biochemical Journal}, publisher={Portland Press Ltd.}, author={DALE, C. Trevor}, year={1998}, month=jan, pages={209–223} }

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