Abstract
Large amounts of Cu-metallothionein were obtained by 2-mercaptoethanol and sodium dodecyl sulphate extractions of the particulate fractions of the liver of pigs given high-Cu2+ diets or rats injected with Cu2+. Three isoproteins were purified from pig liver and characterized on the basis of their physicochemical properties, metal content and amino acid composition. No such pool of Cu-metallothionein was present in the liver of Cu2+-loaded sheep or of rats given Cu2+-supplemented diets.
Dates
Type | When |
---|---|
Created | 10 years ago (Aug. 10, 2015, 4:41 p.m.) |
Deposited | 3 years, 9 months ago (Nov. 25, 2021, 8:22 a.m.) |
Indexed | 2 months, 3 weeks ago (June 10, 2025, 1:28 p.m.) |
Issued | 41 years, 4 months ago (April 15, 1984) |
Published | 41 years, 4 months ago (April 15, 1984) |
Published Print | 41 years, 4 months ago (April 15, 1984) |
@article{Mehra_1984, title={Species differences in the occurrence of copper-metallothionein in the particulate fractions of the liver of copper-loaded animals}, volume={219}, ISSN={1470-8728}, url={http://dx.doi.org/10.1042/bj2190539}, DOI={10.1042/bj2190539}, number={2}, journal={Biochemical Journal}, publisher={Portland Press Ltd.}, author={Mehra, R K and Bremner, I}, year={1984}, month=apr, pages={539–546} }