DOI: 10.1042/bst0340989. Inhibitors of the catalytic domain of mitochondrial ATP synthase

Inhibitors of the catalytic domain of mitochondrial ATP synthase

10.1042/bst0340989

Crossref journal-article

Portland Press Ltd.

Biochemical Society Transactions (288)

Abstract

An understanding of the mechanism of ATP synthase requires an explanation of how inhibitors act. The catalytic F1-ATPase domain of the enzyme has been studied extensively by X-ray crystallography in a variety of inhibited states. Four independent inhibitory sites have been identified by high-resolution structural studies. They are the catalytic site, and the binding sites for the antibiotics aurovertin and efrapeptin and for the natural inhibitor protein, IF1.

Bibliography

Gledhill, J. R., & Walker, J. E. (2006). Inhibitors of the catalytic domain of mitochondrial ATP synthase. Biochemical Society Transactions, 34(5), 989â992.

Authors 2

J.R. Gledhill (first)
J.E. Walker (additional)

References 15 Referenced 22

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{'key': '2021111720233916700_B7', 'first-page': '334', 'volume-title': 'Biophysical and Structural Aspects of Bioenergetics', 'author': 'Walker', 'year': '2005'} / Biophysical and Structural Aspects of Bioenergetics by Walker (2005)
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Dates

Type	When
Created	18 years, 10 months ago (Oct. 25, 2006, 9:28 a.m.)
Deposited	3 years, 9 months ago (Nov. 17, 2021, 5:04 p.m.)
Indexed	1 month, 1 week ago (July 24, 2025, 7:55 a.m.)
Issued	18 years, 11 months ago (Oct. 1, 2006)
Published	18 years, 11 months ago (Oct. 1, 2006)
Published Online	18 years, 10 months ago (Oct. 25, 2006)
Published Print	18 years, 11 months ago (Oct. 1, 2006)

Funders 0

None

BibTeX

@article{Gledhill_2006, title={Inhibitors of the catalytic domain of mitochondrial ATP synthase}, volume={34}, ISSN={1470-8752}, url={http://dx.doi.org/10.1042/bst0340989}, DOI={10.1042/bst0340989}, number={5}, journal={Biochemical Society Transactions}, publisher={Portland Press Ltd.}, author={Gledhill, J.R. and Walker, J.E.}, year={2006}, month=oct, pages={989–992} }

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