DOI: 10.1042/bst0331375. Thiol redox control via thioredoxin and glutaredoxin systems

Thiol redox control via thioredoxin and glutaredoxin systems

10.1042/bst0331375

Crossref journal-article

Portland Press Ltd.

Biochemical Society Transactions (288)

Abstract

The Trx (thioredoxin) and Grx (glutaredoxin) systems control cellular redox potential, keeping a reducing thiol-rich intracellular state, which on generation of reactive oxygen species signals through thiol redox control mechanisms. Here, we give a brief overview of the human Trx and Grx systems. The main part focuses on our current knowledge about mitochondrial Grx2, which facilitates mitochondrial redox homoeostasis during oxidative stress-induced apoptosis.

Bibliography

Holmgren, A., Johansson, C., Berndt, C., LÃ¶nn, M. E., Hudemann, C., & Lillig, C. H. (2005). Thiol redox control via thioredoxin and glutaredoxin systems. Biochemical Society Transactions, 33(6), 1375â1377.

Authors 6

A. Holmgren (first)
C. Johansson (additional)
C. Berndt (additional)
M.E. Lönn (additional)
C. Hudemann (additional)
C.H. Lillig (additional)

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Dates

Type	When
Created	10 years ago (Aug. 11, 2015, 12:17 p.m.)
Deposited	3 years, 9 months ago (Nov. 17, 2021, 5:48 p.m.)
Indexed	1 month ago (Aug. 3, 2025, 12:16 a.m.)
Issued	19 years, 10 months ago (Oct. 26, 2005)
Published	19 years, 10 months ago (Oct. 26, 2005)
Published Online	19 years, 10 months ago (Oct. 26, 2005)
Published Print	19 years, 10 months ago (Oct. 26, 2005)

Funders 0

None

BibTeX

@article{Holmgren_2005, title={Thiol redox control via thioredoxin and glutaredoxin systems}, volume={33}, ISSN={1470-8752}, url={http://dx.doi.org/10.1042/bst0331375}, DOI={10.1042/bst0331375}, number={6}, journal={Biochemical Society Transactions}, publisher={Portland Press Ltd.}, author={Holmgren, A. and Johansson, C. and Berndt, C. and Lönn, M.E. and Hudemann, C. and Lillig, C.H.}, year={2005}, month=oct, pages={1375–1377} }

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