DOI: 10.1039/b819720b. Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

10.1039/b819720b

Crossref journal-article

Royal Society of Chemistry (RSC)

Molecular BioSystems (292)

Bibliography

Tsai, C.-J., del Sol, A., & Nussinov, R. (2009). Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms. Molecular BioSystems, 5(3), 207.

Authors 3

Chung-Jung Tsai (first)
Antonio del Sol (additional)
Ruth Nussinov (additional)

References 50 Referenced 289

10.1038/nchembio.98 / Nat. Chem. Biol. by Goodey (2008)
10.1002/prot.20232 / Proteins: Struct., Funct., Genet. by Gunasekaran (2004)
10.1016/j.jmb.2008.02.034 / J. Mol. Biol. by Tsai (2008)
10.1073/pnas.0404781101 / Proc. Natl. Acad. Sci. U. S. A. by Hardy (2004)
10.1073/pnas.0509418102 / Proc. Natl. Acad. Sci. U. S. A. by Ozkan (2005)
10.1126/science.1157092 / Science by Lange (2008)
10.1126/science.1158818 / Science by Boehr (2008)
10.1110/ps.03259908 / Protein Sci. by Cui (2008)
10.1021/bi060652l / Biochemistry by Clarkson (2006)
10.1021/jm070814r / J. Med. Chem. by Gopi (2008)
10.1039/b717819k / Mol. BioSyst. by Chennubhotla (2008)
10.1021/ja076046a / J. Am. Chem. Soc. by Li (2007)
10.1002/prot.21800 / Proteins: Struct., Funct., Genet. by Daily (2008)
10.1074/jbc.M605512200 / J. Biol. Chem. by Chen (2006)
10.1073/pnas.0711732105 / Proc. Natl. Acad. Sci. U. S. A. by Chi (2008)
10.1016/S0022-2836(65)80285-6 / J. Mol. Biol. by Monod (1965)
10.1021/bi00865a047 / Biochemistry by Koshland (1966)
10.1038/nsb881 / Nat. Struct. Biol. by Suel (2003)
10.1002/prot.20893 / Proteins: Struct., Funct., Genet. by Formaneck (2006)
10.1110/ps.9.1.10 / Protein Sci. by Kumar (2000)
10.1093/protein/12.9.713 / Protein Eng. by Ma (1999)
10.1073/pnas.82.15.5000 / Proc. Natl. Acad. Sci. U. S. A. by Ansari (1985)
10.1038/nsmb1132 / Nat. Struct. Mol. Biol. by Popovych (2006)
10.1007/BF00276625 / Eur. Biophys. J. by Cooper (1984)
10.1016/j.sbi.2003.10.008 / Curr. Opin. Struct. Biol. by Kern (2003)
10.1110/ps.21302 / Protein Sci. by Ma (2002)
10.1073/pnas.0508071103 / Proc. Natl. Acad. Sci. U. S. A. by Camara-Campos (2006)
10.1126/science.286.5438.295 / Science by Lockless (1999)
10.1016/S0092-8674(04)00119-9 / Cell by Shulman (2004)
10.1021/bi701303p / Biochemistry by Niu (2007)
10.1016/j.jmb.2003.11.010 / J. Mol. Biol. by Fuentes (2004)
10.1016/j.jmb.2006.08.076 / J. Mol. Biol. by Fuentes (2006)
10.1021/ja0752080 / J. Am. Chem. Soc. by Dhulesia (2008)
{'key': 'b819720b-(cit34)/*[position()=1]', 'first-page': '478', 'volume': '248', 'author': 'Schreiber', 'year': '1995', 'journal-title': 'J. Mol. Biol.'} / J. Mol. Biol. by Schreiber (1995)
10.1016/0092-8674(84)90278-2 / Cell by Carter (1984)
10.1016/0022-2836(90)90275-Q / J. Mol. Biol. by Horovitz (1990)
10.1016/0022-2836(92)90557-Z / J. Mol. Biol. by Horovitz (1992)
10.1073/pnas.0708120104 / Proc. Natl. Acad. Sci. U. S. A. by Sadovsky (2007)
10.1038/nrm2203 / Nat. Rev. Mol. Cell Biol. by Ubersax (2007)
10.1038/msb4100149 / Mol. Syst. Biol. by Komurov (2007)
10.1016/j.str.2007.01.007 / Structure by Keskin (2007)
10.1074/jbc.M709501200 / J. Biol. Chem. by Friedmann (2008)
10.1016/j.str.2005.03.006 / Structure (London) by Huang (2005)
10.1007/s00018-008-8147-6 / Cell. Mol. Life Sci. by Garg (2008)
{'key': 'b819720b-(cit46)/*[position()=1]', 'author': 'Das', 'year': '2008', 'journal-title': 'J. Biol. Chem.'} / J. Biol. Chem. by Das (2008)
10.1074/jbc.M800112200 / J. Biol. Chem. by Gangloff (2008)
10.1016/j.jmb.2007.05.013 / J. Mol. Biol. by Heddle (2007)
10.1016/S0022-2836(02)00940-3 / J. Mol. Biol. by McElroy (2002)
10.1021/bi702330t / Biochemistry by Boyer (2008)
10.1073/pnas.0707401105 / Proc. Natl. Acad. Sci. U. S. A. by Liu (2008)

Dates

Type	When
Created	16 years, 8 months ago (Jan. 7, 2009, 4:30 a.m.)
Deposited	1 year, 4 months ago (April 17, 2024, 5:24 a.m.)
Indexed	6 days, 21 hours ago (Aug. 31, 2025, 7:30 p.m.)
Issued	16 years, 8 months ago (Jan. 1, 2009)
Published	16 years, 8 months ago (Jan. 1, 2009)
Published Print	16 years, 8 months ago (Jan. 1, 2009)

Funders 0

None

BibTeX

@article{Tsai_2009, title={Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms}, volume={5}, ISSN={1742-2051}, url={http://dx.doi.org/10.1039/b819720b}, DOI={10.1039/b819720b}, number={3}, journal={Molecular BioSystems}, publisher={Royal Society of Chemistry (RSC)}, author={Tsai, Chung-Jung and del Sol, Antonio and Nussinov, Ruth}, year={2009}, pages={207} }

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    },
    {
      "key": "b819720b-(cit11)/*[position()=1]",
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      "first-page": "287",
      "DOI": "10.1039/b717819k",
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      "author": "Chennubhotla",
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    {
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    {
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      "author": "Chen",
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    {
      "key": "b819720b-(cit15)/*[position()=1]",
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      "DOI": "10.1021/bi00865a047",
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    {
      "key": "b819720b-(cit18)/*[position()=1]",
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      "first-page": "59",
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    },
    {
      "key": "b819720b-(cit19)/*[position()=1]",
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    {
      "key": "b819720b-(cit20)/*[position()=1]",
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    {
      "key": "b819720b-(cit21)/*[position()=1]",
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    {
      "key": "b819720b-(cit22)/*[position()=1]",
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      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "b819720b-(cit23)/*[position()=1]",
      "doi-asserted-by": "crossref",
      "first-page": "831",
      "DOI": "10.1038/nsmb1132",
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      "author": "Popovych",
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      "journal-title": "Nat. Struct. Mol. Biol."
    },
    {
      "key": "b819720b-(cit24)/*[position()=1]",
      "doi-asserted-by": "crossref",
      "first-page": "103",
      "DOI": "10.1007/BF00276625",
      "volume": "11",
      "author": "Cooper",
      "year": "1984",
      "journal-title": "Eur. Biophys. J."
    },
    {
      "key": "b819720b-(cit25)/*[position()=1]",
      "doi-asserted-by": "crossref",
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      "DOI": "10.1016/j.sbi.2003.10.008",
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      "author": "Kern",
      "year": "2003",
      "journal-title": "Curr. Opin. Struct. Biol."
    },
    {
      "key": "b819720b-(cit26)/*[position()=1]",
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      "DOI": "10.1110/ps.21302",
      "volume": "11",
      "author": "Ma",
      "year": "2002",
      "journal-title": "Protein Sci."
    },
    {
      "key": "b819720b-(cit27)/*[position()=1]",
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      "first-page": "3034",
      "DOI": "10.1073/pnas.0508071103",
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      "year": "2006",
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      "key": "b819720b-(cit28)/*[position()=1]",
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      "journal-title": "Science"
    },
    {
      "key": "b819720b-(cit29)/*[position()=1]",
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      "first-page": "417",
      "DOI": "10.1016/S0092-8674(04)00119-9",
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      "author": "Shulman",
      "year": "2004",
      "journal-title": "Cell"
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    {
      "key": "b819720b-(cit30)/*[position()=1]",
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      "first-page": "15042",
      "DOI": "10.1021/bi701303p",
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      "author": "Niu",
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    },
    {
      "key": "b819720b-(cit31)/*[position()=1]",
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      "first-page": "1105",
      "DOI": "10.1016/j.jmb.2003.11.010",
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      "author": "Fuentes",
      "year": "2004",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "b819720b-(cit32)/*[position()=1]",
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      "first-page": "337",
      "DOI": "10.1016/j.jmb.2006.08.076",
      "volume": "364",
      "author": "Fuentes",
      "year": "2006",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "b819720b-(cit33)/*[position()=1]",
      "doi-asserted-by": "crossref",
      "first-page": "8931",
      "DOI": "10.1021/ja0752080",
      "volume": "130",
      "author": "Dhulesia",
      "year": "2008",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "b819720b-(cit34)/*[position()=1]",
      "first-page": "478",
      "volume": "248",
      "author": "Schreiber",
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    {
      "key": "b819720b-(cit35)/*[position()=1]",
      "doi-asserted-by": "crossref",
      "first-page": "835",
      "DOI": "10.1016/0092-8674(84)90278-2",
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      "author": "Carter",
      "year": "1984",
      "journal-title": "Cell"
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      "key": "b819720b-(cit36)/*[position()=1]",
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      "first-page": "613",
      "DOI": "10.1016/0022-2836(90)90275-Q",
      "volume": "214",
      "author": "Horovitz",
      "year": "1990",
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    {
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      "author": "Horovitz",
      "year": "1992",
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    },
    {
      "key": "b819720b-(cit38)/*[position()=1]",
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      "first-page": "19813",
      "DOI": "10.1073/pnas.0708120104",
      "volume": "104",
      "author": "Sadovsky",
      "year": "2007",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "b819720b-(cit39)/*[position()=1]",
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      "first-page": "530",
      "DOI": "10.1038/nrm2203",
      "volume": "8",
      "author": "Ubersax",
      "year": "2007",
      "journal-title": "Nat. Rev. Mol. Cell Biol."
    },
    {
      "key": "b819720b-(cit40)/*[position()=1]",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1038/msb4100149",
      "volume": "3",
      "author": "Komurov",
      "year": "2007",
      "journal-title": "Mol. Syst. Biol."
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    {
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      "first-page": "341",
      "DOI": "10.1016/j.str.2007.01.007",
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    {
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      "first-page": "14781",
      "DOI": "10.1074/jbc.M709501200",
      "volume": "283",
      "author": "Friedmann",
      "year": "2008",
      "journal-title": "J. Biol. Chem."
    },
    {
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      "first-page": "755",
      "DOI": "10.1016/j.str.2005.03.006",
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      "journal-title": "Structure (London)"
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    {
      "issue": "20",
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      "volume": "65",
      "author": "Garg",
      "year": "2008",
      "journal-title": "Cell. Mol. Life Sci."
    },
    {
      "key": "b819720b-(cit46)/*[position()=1]",
      "author": "Das",
      "year": "2008",
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    {
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      "first-page": "154",
      "DOI": "10.1016/j.jmb.2007.05.013",
      "volume": "371",
      "author": "Heddle",
      "year": "2007",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "b819720b-(cit49)/*[position()=1]",
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