Crossref journal-article
Springer Science and Business Media LLC
Scientific Reports (297)
Abstract

AbstractWe used soft X-ray three-dimensional imaging to quantify the mass of superparamagnetic iron oxide nanoparticles (SPION) within whole cells, by exploiting the iron oxide differential absorption contrast. Near-edge absorption soft X-ray nanotomography (NEASXT) combines whole-cell 3D structure determination at 50 nm resolution, with 3D elemental mapping and high throughput. We detected three-dimensional distribution of SPIONs within cells with 0.3 g/cm3 sensitivity, sufficient for detecting the density corresponding to a single nanoparticle.

Bibliography

Conesa, J. J., Otón, J., Chiappi, M., Carazo, J. M., Pereiro, E., Chichón, F. J., & Carrascosa, J. L. (2016). Intracellular nanoparticles mass quantification by near-edge absorption soft X-ray nanotomography. Scientific Reports, 6(1).

Authors 7
  1. Jose Javier Conesa (first)
  2. Joaquín Otón (additional)
  3. Michele Chiappi (additional)
  4. Jose María Carazo (additional)
  5. Eva Pereiro (additional)
  6. Francisco Javier Chichón (additional)
  7. José L. Carrascosa (additional)
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Dates
Type When
Created 9 years, 5 months ago (March 10, 2016, 5:02 a.m.)
Deposited 2 years, 7 months ago (Jan. 4, 2023, 8:13 a.m.)
Indexed 1 month ago (July 16, 2025, 9:35 a.m.)
Issued 9 years, 5 months ago (March 10, 2016)
Published 9 years, 5 months ago (March 10, 2016)
Published Online 9 years, 5 months ago (March 10, 2016)
Funders 0

None

@article{Conesa_2016, title={Intracellular nanoparticles mass quantification by near-edge absorption soft X-ray nanotomography}, volume={6}, ISSN={2045-2322}, url={http://dx.doi.org/10.1038/srep22354}, DOI={10.1038/srep22354}, number={1}, journal={Scientific Reports}, publisher={Springer Science and Business Media LLC}, author={Conesa, Jose Javier and Otón, Joaquín and Chiappi, Michele and Carazo, Jose María and Pereiro, Eva and Chichón, Francisco Javier and Carrascosa, José L.}, year={2016}, month=mar }