DOI: 10.1038/srep03287. DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride

DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride

10.1038/srep03287

Crossref journal-article

Springer Science and Business Media LLC

Scientific Reports (297)

Abstract

AbstractUltra-thin solid-state nanopore with good wetting property is strongly desired to achieve high spatial resolution for DNA sequencing applications. Atomic thick hexagonal boron nitride (h-BN) layer provides a promising two-dimensional material for fabricating solid-state nanopores. Due to its good oxidation resistance, the hydrophilicity of h-BN nanopore device can be significantly improved by UV-Ozone treatment. The contact angle of a KCl-TE droplet on h-BN layer can be reduced from 57° to 26° after the treatment. Abundant DNA translocation events have been observed in such devices and strong DNA-nanopore interaction has been revealed in pores smaller than 10 nm in diameter. The 1/f noise level is closely related to the area of suspended h-BN layer and it is significantly reduced in smaller supporting window. The demonstrated performance in h-BN nanopore paves the way towards base discrimination in a single DNA molecule.

Bibliography

Zhou, Z., Hu, Y., Wang, H., Xu, Z., Wang, W., Bai, X., Shan, X., & Lu, X. (2013). DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride. Scientific Reports, 3(1).

Authors 8

Zhi Zhou (first)
Ying Hu (additional)
Hao Wang (additional)
Zhi Xu (additional)
Wenlong Wang (additional)
Xuedong Bai (additional)
Xinyan Shan (additional)
Xinghua Lu (additional)

References 27 Referenced 107

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Dates

Type	When
Created	11 years, 9 months ago (Nov. 21, 2013, 5:19 a.m.)
Deposited	2 years, 7 months ago (Jan. 5, 2023, 11:48 p.m.)
Indexed	1 month, 3 weeks ago (July 3, 2025, 12:27 p.m.)
Issued	11 years, 9 months ago (Nov. 21, 2013)
Published	11 years, 9 months ago (Nov. 21, 2013)
Published Online	11 years, 9 months ago (Nov. 21, 2013)

Funders 0

None

BibTeX

@article{Zhou_2013, title={DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride}, volume={3}, ISSN={2045-2322}, url={http://dx.doi.org/10.1038/srep03287}, DOI={10.1038/srep03287}, number={1}, journal={Scientific Reports}, publisher={Springer Science and Business Media LLC}, author={Zhou, Zhi and Hu, Ying and Wang, Hao and Xu, Zhi and Wang, Wenlong and Bai, Xuedong and Shan, Xinyan and Lu, Xinghua}, year={2013}, month=nov }

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