DOI: 10.1038/sj.mt.6300331. AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method

AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method

10.1038/sj.mt.6300331

Crossref journal-article

Elsevier BV

Molecular Therapy (78)

Bibliography

Klein, R. L., Dayton, R. D., Tatom, J. B., Henderson, K. M., & Henning, P. P. (2008). AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method. Molecular Therapy, 16(1), 89â96.

Authors 5

Ronald L Klein (first)
Robert D Dayton (additional)
Jason B Tatom (additional)
Karen M Henderson (additional)
Phillip P Henning (additional)

References 27 Referenced 163

10.2174/1566523054065057 / Curr Gene Ther / New recombinant serotypes of AAV vectors by Gao (2005)
10.1073/pnas.182412299 / Proc Natl Acad Sci USA / Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy by Gao (2002)
10.1016/j.nbd.2005.02.001 / Neurobiol Dis / Tau gene transfer, but not alpha-synuclein, induces both progressive dopamine neuron degeneration and rotational behavior in the rat by Klein (2005)
10.1016/j.ymthe.2005.11.009 / Mol Ther / Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders by Mandel (2006)
10.1073/pnas.97.7.3428 / Proc Natl Acad Sci USA / Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system by Davidson (2000)
10.1016/j.ymthe.2004.05.024 / Mol Ther / Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system by Burger (2004)
10.1128/JVI.78.13.6808-6817.2004 / J Virol / Transduction profiles of recombinant adeno-associated virus vectors derived from serotypes 2 and 5 in the nigrostriatal system of rats by Paterna (2004)
10.1016/j.ymthe.2005.10.008 / Mol Ther / Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins by Klein (2006)
10.1016/j.neuroscience.2005.11.057 / Neuroscience / Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain by Broekman (2006)
10.1089/hum.2006.17.807 / Hum Gene Ther / Enhanced gene transfer efficiency in the murine striatum and an orthotopic glioblastoma tumor model, using AAV-7- and AAV-8-pseudotyped vectors by Harding (2006)
10.1089/hum.2006.178 / Hum Gene Ther / Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain by Taymans (2007)
10.1038/sj.mt.6300227 / Mol Ther / Time course of transgene expression after intrastriatal psuedotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 transduction in the rat by Reimsnider (2007)
10.1089/hum.2005.16.781 / Human Gene Ther / Recombinant adeno-associated viral vectors in the nervous system by Burger (2005)
10.1128/JVI.79.1.214-224.2005 / J Virol / Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice by Nakai (2005)
10.1038/nbt1073 / Nat Biotechnol / Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart by Wang (2005)
10.1161/01.RES.0000237661.18885.f6 / Circ Res / Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo by Pacak (2006)
10.1016/j.ymthe.2006.03.014 / Mol Ther / Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8 by Inagaki (2006)
10.1016/j.ymthe.2005.11.015 / Mol Ther / Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and rh10 in the mouse brain by Cearley (2006)
10.1038/sj.mt.6300049 / Mol Ther / Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 Rhesus Macaque-derives adeno-associated virus vector by Sondhi (2007)
10.1128/JVI.74.19.9281-9293.2000 / J Virol / Monoclonal antibodies against adeno-associated virus type 2 (AAV-2). capsid: epitope mapping and identification of capsid domains involved in AAV-2 interaction and neutralization of AAV-2 infection by Wobus (2000)
10.1016/S0165-0270(00)00183-7 / J Neurosci Methods / Adeno-associated virus vectors: activity and applications in the central nervous system by Peel (2000)
10.1016/j.brainresprot.2004.08.001 / Brain Res Brain Res Protoc / Recombinant adeno-associated virus serotype 2 effectively transduces primary rat brain astrocytes and microglia by Gong (2004)
10.1016/S1046-2023(02)00220-7 / Methods / Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors by Zolotukhin (2002)
10.1023/A:1010661131403 / J Neurooncol / Delivery of cell cycle genes to block astrocytoma growth by Fueyo (2001)
10.1016/j.brainresrev.2004.05.003 / Brain Res Brain Res Rev / A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis by Barbeito (2004)
10.1016/j.neurobiolaging.2004.01.007 / Neurobiol Aging / Contribution of glial cells to the deveolpment of amyloid plaques in Alzheimer's disease by Nagele (2004)
{'key': '10.1038/sj.mt.6300331_bib27', 'series-title': 'The Rat Brain in Stereotaxic Coordinates', 'author': 'Paxinos', 'year': '1998'} / The Rat Brain in Stereotaxic Coordinates by Paxinos (1998)

Dates

Type	When
Created	17 years, 10 months ago (Oct. 23, 2007, 2:52 a.m.)
Deposited	6 years, 7 months ago (Jan. 3, 2019, 6:56 a.m.)
Indexed	1 month ago (July 30, 2025, 11:30 a.m.)
Issued	17 years, 7 months ago (Jan. 1, 2008)
Published	17 years, 7 months ago (Jan. 1, 2008)
Published Print	17 years, 7 months ago (Jan. 1, 2008)

Funders 0

None

BibTeX

@article{Klein_2008, title={AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method}, volume={16}, ISSN={1525-0016}, url={http://dx.doi.org/10.1038/sj.mt.6300331}, DOI={10.1038/sj.mt.6300331}, number={1}, journal={Molecular Therapy}, publisher={Elsevier BV}, author={Klein, Ronald L and Dayton, Robert D and Tatom, Jason B and Henderson, Karen M and Henning, Phillip P}, year={2008}, month=jan, pages={89–96} }

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