DOI: 10.1038/sj.mp.4001145. Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice

Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice

10.1038/sj.mp.4001145

Crossref journal-article

Springer Science and Business Media LLC

Molecular Psychiatry (297)

Bibliography

Xu, R., Hranilovic, D., Fetsko, L. A., Bucan, M., & Wang, Y. (2002). Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice. Molecular Psychiatry, 7(10), 1075â1082.

Authors 5

R Xu (first)
D Hranilovic (additional)
L A Fetsko (additional)
M Bucan (additional)
Y Wang (additional)

References 29 Referenced 58

Carlsson A . Thirty years of dopamine research Adv Neurol 1993 60: 1–10 / Adv Neurol by A Carlsson (1993)
Nordstrom A-L, Farde L, Wiesel F-A, Forslund K, Pauli S, Halldin C et al. Central D2- dopamine receptor occupancy in relation to antipsychotic drug effects: a double-blind PET study of schizophrenic patients Biol Psychiatry 1993 33: 227–235 (10.1016/0006-3223(93)90288-O) / Biol Psychiatry by A-L Nordstrom (1993)
Farde L, Nordstrom A-L, Wiesel F-A, Pauli S, Halldin C, Sedvall G . PET-analysis of central D-2 and D2-dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine — relation to extrapyramidal side effects Arch Gen Psychiatry 1992 49: 538–544 (10.1001/archpsyc.1992.01820070032005) / Arch Gen Psychiatry by L Farde (1992)
Langtry HD, Clissold SP . Pergolide — a review of its pharmacological properties and therapeutic potential in Parkinson's disease Drugs 1990 39: 491–506 (10.2165/00003495-199039030-00009) / Drugs by HD Langtry (1990)
Grillon C, Ameli R, Charney DS, Krystal J, Braff D . Startle gating deficits occur across prepulse intensities in schizophrenic patients Biol Psychiatry 1992 32: 939–943 (10.1016/0006-3223(92)90183-Z) / Biol Psychiatry by C Grillon (1992)
Swerdlow NR, Braff DL, Taaid N, Geyer MA . Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients Arch Gen Psychiatry 1994 51: 139–154 (10.1001/archpsyc.1994.03950020063007) / Arch Gen Psychiatry by NR Swerdlow (1994)
Peng RY, Mansbach RS, Braff DL, Geyer MA . A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Indications for dopaminergic abnormalities in schizophrenia Neuropsychopharmacology 1990 3: 211–218 / Neuropsychopharmacology by RY Peng (1990)
Abduljawad KA, Langley RW, Bradshaw CM, Szabadi E . Effects of bromocriptine and haloperidol on prepulse inhibition of the acoustic startle response in man J Psychopharmacol 1998 12: 239–245 (10.1177/026988119801200302) / J Psychopharmacol by KA Abduljawad (1998)
Ralph RJ, Varty GB, Kely MA, Wang YM, Caron MG, Rubinstein M et al. The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice J Neurosci 1999 19: 4627–4633 (10.1523/JNEUROSCI.19-11-04627.1999) / J Neurosci by RJ Ralph (1999)
Ralph RJ, Paulus MP, Fumagalli F, Caron MG, Geyer MA . Prepulse inhibition deficits and perserverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists J Neurosci 2001 21: 305–313 (10.1523/JNEUROSCI.21-01-00305.2001) / J Neurosci by RJ Ralph (2001)
Wang Y, Xu R, Toshikuni S, Tonegawa S, Kung M-P, Sankoorikal E-B . Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions J Neurosci 2000 20: 8305–8314 (10.1523/JNEUROSCI.20-22-08305.2000) / J Neurosci by Y Wang (2000)
Neve KA, Neve RL, Fidel S, Janowsky A, Higgins GA . Increased abundance of alternatively spliced forms of D2 dopamine receptor mRNA after denervation Proc Natl Acad Sci USA 1991 88: 2802–2806 (10.1073/pnas.88.7.2802) / Proc Natl Acad Sci USA by KA Neve (1991)
Vukhac K-L, Sankoorikal E-B, Wang Y . Dopamine D2L receptor- and age-related reduction in offensive aggression NeuroReport 2001 12: 1035–1038 (10.1097/00001756-200104170-00034) / NeuroReport by K-L Vukhac (2001)
Nolan PM, Kapfhamer D, Bucan M . Random mutagenesis screen for dominant behavioral mutations in mice Methods: A Companion to Meth Enzymol 1997 13: 379–395 (10.1006/meth.1997.0545) / Methods: A Companion to Meth Enzymol by PM Nolan (1997)
Tarantino LM, Gould TJ, Druhan JP, Bucan M . Behavior and mutagenesis screens: the importance of baseline analysis of inbred strains Mammalian Genome 2000 11: 555–564 (10.1007/s003350010107) / Mammalian Genome by LM Tarantino (2000)
Seeman P, Tallerico T . Antipsychotic drugs which elicit little or no Parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors Mol Psychiatry 1998 3: 123–134 (10.1038/sj.mp.4000336) / Mol Psychiatry by P Seeman (1998)
Castro SW, Strange PG . Differences in the ligand binding properties of the short and long versions of the D2 dopamine receptor J Neurochem 1993 60: 372–375 (10.1111/j.1471-4159.1993.tb05863.x) / J Neurochem by SW Castro (1993)
Malmberg A, Jackson DM, Eriksson A, Mohell N . Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors Mol Pharmacol 1993 43: 749–754 / Mol Pharmacol by A Malmberg (1993)
Usiello A, Baik J-H, Rouge-Pont F, Picetti R, Dierich A, LeMeur M et al. Distinct functions of the two isoforms of dopamine D2 receptors Nature 2000 408: 199–203 (10.1038/35041572) / Nature by A Usiello (2000)
Hoffman DC, Donovan H . Catalepsy as a rodent model for detecting antipsychotic drugs with extrapyramidal side effect liability Psychopharmacology 1995 120: 128–133 (10.1007/BF02246184) / Psychopharmacology by DC Hoffman (1995)
Kelly MA, Rubinstein M, Phillips TJ, Lessov CN, Burkhart-Kasch S, Zhang G et al. Locomotor activity in D2 dopamine receptor deficient mice is determined by gene dosage, genetic background, and developmental adaptations J Neurosci 1998 18: 3470–3479 (10.1523/JNEUROSCI.18-09-03470.1998) / J Neurosci by MA Kelly (1998)
Xu M, Moratalla R, Gold LH, Hiroi N, Koob GF, Graybiel AM, Tonegawa S . Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses Cell 1994 79: 729–742 (10.1016/0092-8674(94)90557-6) / Cell by M Xu (1994)
Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB et al. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine Nature 1991 350: 610–614 (10.1038/350610a0) / Nature by HH Van Tol (1991)
Bristow LJ, Kramer MS, Kulagowski J, Patel S, Ragan CI, Seabrook GR . Schizophrenia and L-745,870, a novel dopamine D4 receptor antagonist Trends Pharmacol Sci 1997 18: 186–188 (10.1016/S0165-6147(97)90618-0) / Trends Pharmacol Sci by LJ Bristow (1997)
Davis M, Svensson TH, Aghajanian GK . Effects of d- and l-amphetamine on habituation and sensitization of the acoustic startle response in rats Psychopharmacology 1975 43: 1–11 (10.1007/BF00437607) / Psychopharmacology by M Davis (1975)
Vandergriff J, Kallman MJ, Rasmussen K . Moxonidine, a selective imidazoline-1 receptor agonist, suppresses the effects of ethanol withdrawal on the acoustic startle response in rats Biol Psychiatry 2000 15: 874–879 (10.1016/S0006-3223(00)00229-8) / Biol Psychiatry by J Vandergriff (2000)
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Wood GK, Tomasiewicz H, Rutishauser U, Magnuson T, Quirion R, Rochford J, Srivastava LK . NCAM-180 knockout mice display increased lateral ventricle size and reduced prepulse inhibition of startle NeuroReport 1998 9: 461–466 (10.1097/00001756-199802160-00019) / NeuroReport by GK Wood (1998)
Swerdlow NR, Braff DL, Geyer MA . Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon Behav Pharmacol 2000 11: 185–204 (10.1097/00008877-200006000-00002) / Behav Pharmacol by NR Swerdlow (2000)

Dates

Type	When
Created	22 years, 8 months ago (Dec. 13, 2002, 6:57 a.m.)
Deposited	3 years, 5 months ago (March 31, 2022, 11:31 p.m.)
Indexed	1 week, 6 days ago (Aug. 19, 2025, 6:15 a.m.)
Issued	22 years, 9 months ago (Dec. 1, 2002)
Published	22 years, 9 months ago (Dec. 1, 2002)
Published Online	22 years, 8 months ago (Dec. 12, 2002)
Published Print	22 years, 9 months ago (Dec. 1, 2002)

Funders 0

None

BibTeX

@article{Xu_2002, title={Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice}, volume={7}, ISSN={1476-5578}, url={http://dx.doi.org/10.1038/sj.mp.4001145}, DOI={10.1038/sj.mp.4001145}, number={10}, journal={Molecular Psychiatry}, publisher={Springer Science and Business Media LLC}, author={Xu, R and Hranilovic, D and Fetsko, L A and Bucan, M and Wang, Y}, year={2002}, month=dec, pages={1075–1082} }

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