DOI: 10.1038/sj.leu.2401619. Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia

Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia

10.1038/sj.leu.2401619

Crossref journal-article

Springer Science and Business Media LLC

Leukemia (297)

Bibliography

Zhou, M., Gu, L., Abshire, T., Homans, A., Billett, A., Yeager, A., & Findley, H. (2000). Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia. Leukemia, 14(1), 61â67.

Authors 7

M Zhou (first)
L Gu (additional)
TC Abshire (additional)
A Homans (additional)
AL Billett (additional)
AM Yeager (additional)
HW Findley (additional)

References 21 Referenced 72

Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B . Amplification of a gene encoding a p53-associated protein in human sarcomas Nature 1992 358: 80–83 (10.1038/358080a0) / Nature by JD Oliner (1992)
Chen J, Wu X, Lin J, Levine AJ . mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein Mol Cell Biol 1996 16: 2445–2452 (10.1128/MCB.16.5.2445) / Mol Cell Biol by J Chen (1996)
Wu X, Bayle J, Olson D, Levine A . The p53-MDM2 autoregulatory feedback loop Genes Dev 1993 7: 1126–1132 (10.1101/gad.7.7a.1126) / Genes Dev by X Wu (1993)
Haupt Y, Barak Y, Oren M . Cell type-specific inhibition of p53-mediated apoptosis by mdm2 EMBO J 1996 15: 1596–1606 (10.1002/j.1460-2075.1996.tb00504.x) / EMBO J by Y Haupt (1996)
Piette J, Neel H, Marechal V . MDM2: keeping p53 under control Oncogene 1997 15: 1001–1010 (10.1038/sj.onc.1201432) / Oncogene by J Piette (1997)
Sigalas I, Calvert AH, Anderson JJ, Neal DE, Lunec J . Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer Nature Med 1996 2: 912–917 (10.1038/nm0896-912) / Nature Med by I Sigalas (1996)
Lundgren K, Luna R, McNeill YB, Emerick EP, Spencer B, Barfield CR, Lozana G, Rosenberg MP, Finlay CA . Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53 Genes Dev 1997 11: 714–725 (10.1101/gad.11.6.714) / Genes Dev by K Lundgren (1997)
Jones SN, Hancock AR, Vogel H, Donehower LA, Bradly A . Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis Proc Natl Acad Sci USA 1998 95: 15608–15612 (10.1073/pnas.95.26.15608) / Proc Natl Acad Sci USA by SN Jones (1998)
Quesnel B, Preudhomme C, Oscier D, Lepelley P, O'Hooghe MC, Facon T, Zandecki M, Fenaux P . Overexpression of the mdm-2 gene is found in some cases of haematological malignancies Br J Haematol 1994 88: 415–418 (10.1111/j.1365-2141.1994.tb05044.x) / Br J Haematol by B Quesnel (1994)
Bueso-Ramos CE, Yang Y, deLeon E, McCown P, Stass SA, Albitar M . The humanMDM2 oncogene is overexpressed in leukemias Blood 1993 82: 2617–2623 (10.1182/blood.V82.9.2617.2617) / Blood by CE Bueso-Ramos (1993)
Zhou M, Yeager AM, Smith SD, Findley HW . Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene Blood 1995 85: 1608–1614 (10.1182/blood.V85.6.1608.bloodjournal8561608) / Blood by M Zhou (1995)
Marks DI, Kurz BW, Link MP, Ng E, Shuster JJ, Lauer SJ, Brodsky I, Haines DS . High incidence of potential p53 inactivation in poor outcome childhood acute lymphoblastic leukemia at diagnosis Blood 1996 87: 1155–1161 (10.1182/blood.V87.3.1155.bloodjournal8731155) / Blood by DI Marks (1996)
Marks DI, Kurz BW, Link MP, Ng E, Shuster JJ, Lauer SJ, Carroll D, Brodsky I, Haines DS . Altered expression of p53 and mdm-2 proteins at diagnosis is associated with early treatment failure in childhood acute lymphoblastic leukemia J Clin Oncol 1997 15: 1158–1162 (10.1200/JCO.1997.15.3.1158) / J Clin Oncol by DI Marks (1997)
Gustafsson B, Stal O, Gustafsson B . Overexpression of MDM2 in acute childhood lymphoblastic leukemia Ped Hematol Oncol 1998 15: 519–526 (10.3109/08880019809018313) / Ped Hematol Oncol by B Gustafsson (1998)
Poplack DG . Acute lymphoblastic leukemia. In: Pizzo P, Poplack DG (eds) . Principles and Practice of Pediatric Oncology JB Lippincott: Philadelphia, PA 1997 433 / Acute lymphoblastic leukemia. by DG Poplack (1997)
Roehm N, Rodgers G, Hatfield S, Glasebrook A . An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT J Immunol Meth 1991 142: 257–265 (10.1016/0022-1759(91)90114-U) / J Immunol Meth by N Roehm (1991)
Rothenberg ML, Mickley L, Cole DE . Expression of the mdr-1/P-170 gene in patients with acute lymphoblastic leukemia Blood 1989 74: 1388–1395 (10.1182/blood.V74.4.1388.1388) / Blood by ML Rothenberg (1989)
Stammler G, Sauerbrey A, Volm M . Determination of DNA topoisomerase II in newly diagnosed childhood acute lymphoblastic leukemia by immunocytotochemistry and RT-PCR Cancer Lett 1994 84: 141–147 (10.1016/0304-3835(94)90368-9) / Cancer Lett by G Stammler (1994)
Klumper E, Giaccone G, Pieters R, Broekema G, van Arke-Otte J, van Wering ER, Kaspers GJ, Veerman AJ . Topoisomerase Na gene expression in childhood acute lymphoblastic leukemia Leukemia 1995 9: 1653–1660 / Leukemia by E Klumper (1995)
Wada M, Bartram CR, Nakamura H, Hackiya M, Chen D-L, Borenstein J, Miller CW, Ludwig L, Hansen-Hagge TE, Ludwig WD, Reiter A, Mizoguchi H, Koeffler HP . Analysis of p53 mutations in a large series of lymphoid malignancies of childhood Blood 1993 82: 3163–3169 (10.1182/blood.V82.10.3163.3163) / Blood by M Wada (1993)
Diccianni MB, Yu J, Hsiao M, Mukherjee S, Shao L-E, Yu AL . Clinical significance of p53 mutations in relapsed T-cell acute lymphoblastic leukemia Blood 1994 84: 3105–3112 (10.1182/blood.V84.9.3105.3105) / Blood by MB Diccianni (1994)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 4, 2002, 2:26 p.m.)
Deposited	3 years, 4 months ago (March 31, 2022, 5:10 p.m.)
Indexed	3 months, 3 weeks ago (May 2, 2025, 9:30 a.m.)
Issued	25 years, 7 months ago (Jan. 1, 2000)
Published	25 years, 7 months ago (Jan. 1, 2000)
Published Online	25 years, 7 months ago (Jan. 6, 2000)
Published Print	25 years, 7 months ago (Jan. 1, 2000)

Funders 0

None

BibTeX

@article{Zhou_2000, title={Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia}, volume={14}, ISSN={1476-5551}, url={http://dx.doi.org/10.1038/sj.leu.2401619}, DOI={10.1038/sj.leu.2401619}, number={1}, journal={Leukemia}, publisher={Springer Science and Business Media LLC}, author={Zhou, M and Gu, L and Abshire, TC and Homans, A and Billett, AL and Yeager, AM and Findley, HW}, year={2000}, month=jan, pages={61–67} }

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