Stabilized plasmid-lipid particles for systemic gene therapy
10.1038/sj.gt.3301308
Crossref journal-article
Springer Science and Business Media LLC
Gene Therapy (297)
Bibliography

Tam, P., Monck, M., Lee, D., Ludkovski, O., Leng, E. C., Clow, K., Stark, H., Scherrer, P., Graham, R. W., & Cullis, P. R. (2000). Stabilized plasmid-lipid particles for systemic gene therapy. Gene Therapy, 7(21), 1867–1874.

Authors 10
  1. P Tam (first)
  2. M Monck (additional)
  3. D Lee (additional)
  4. O Ludkovski (additional)
  5. E C Leng (additional)
  6. K Clow (additional)
  7. H Stark (additional)
  8. P Scherrer (additional)
  9. R W Graham (additional)
  10. P R Cullis (additional)
References 29 Referenced 127
  1. Huard J et al. The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants Gene Therapy 1995 2: 107–115 / Gene Therapy by J Huard (1995)
  2. Worgall S, Wolff G, Falck PE, Crystal RG . Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration Hum Gene Ther 1997 8: 37–44 (10.1089/hum.1997.8.1-37) / Hum Gene Ther by S Worgall (1997)
  3. Zhu N, Liggitt D, Liu Y, Debs R . Systemic gene expression after intravenous DNA delivery into adult mice Science 1993 261: 209–211 (10.1126/science.7687073) / Science by N Zhu (1993)
  4. Thierry AR et al. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice Proc Natl Acad Sci USA 1995 92: 9742–9746 (10.1073/pnas.92.21.9742) / Proc Natl Acad Sci USA by AR Thierry (1995)
  5. Li S, Huang L . In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes Gene Therapy 1997 4: 891–900 (10.1038/sj.gt.3300482) / Gene Therapy by S Li (1997)
  6. Liu Y et al. Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery Nat Biotechnol 1997 15: 167–173 (10.1038/nbt0297-167) / Nat Biotechnol by Y Liu (1997)
  7. Templeton NS et al. Improved DNA: liposome complexes for increased systemic delivery and gene expression Nat Biotechnol 1997 15: 647–652 (10.1038/nbt0797-647) / Nat Biotechnol by NS Templeton (1997)
  8. Huang L, Li S . Liposomal gene delivery: a complex package Nat Biotechnol 1997 15: 620–621 (10.1038/nbt0797-620) / Nat Biotechnol by L Huang (1997)
  9. Proffitt RT et al. Liposomal blockade of the reticuloendothelial system: improved tumor imaging with small unilamellar vesicles Science 1983 220: 502–505 (10.1126/science.6836294) / Science by RT Proffitt (1983)
  10. Gabizon A, Papahadjopoulos D . Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors Proc Natl Acad Sci USA 1988 85: 6949–6953 (10.1073/pnas.85.18.6949) / Proc Natl Acad Sci USA by A Gabizon (1988)
  11. Chonn A, Cullis PR . Recent advances in liposomal drug-delivery systems Curr Opin Biotechnol 1995 6: 698–708 (10.1016/0958-1669(95)80115-4) / Curr Opin Biotechnol by A Chonn (1995)
  12. Wheeler JJ et al. Stabilized plasmid-lipid particles: construction and characterization Gene Therapy 1999 6: 271–281 (10.1038/sj.gt.3300821) / Gene Therapy by JJ Wheeler (1999)
  13. Mimms LT et al. Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside Biochemistry 1981 20: 833–840 (10.1021/bi00507a028) / Biochemistry by LT Mimms (1981)
  14. Mayer LD et al. Comparison of free and liposome encapsulated doxorubicin tumor drug uptake and antitumor efficacy in the SC115 murine mammary tumor Cancer Lett 1990 53: 183–190 (10.1016/0304-3835(90)90212-G) / Cancer Lett by LD Mayer (1990)
  15. Roerdink F et al. The involvement of parenchymal, Kuppfer and endothelial cells in the hepatic uptake of intravenously injected liposomes. Effects of lanthanum and gadolinium salts Biochim Biophys Acta 1981 677: 79–89 (10.1016/0304-4165(81)90148-3) / Biochim Biophys Acta by F Roerdink (1981)
  16. Mortimer I et al. Cationic lipid-mediated transfection of cells in culture requires mitotic activity Gene Therapy 1999 6: 403–411 (10.1038/sj.gt.3300837) / Gene Therapy by I Mortimer (1999)
  17. Lewis RJ, Huang JH, Pecora R . Rotational and translational motion of supercoiled plasmids in solution Macromolecules 1985 18: 944–948 (10.1021/ma00147a022) / Macromolecules by RJ Lewis (1985)
  18. Gnant MFX et al. Sensitization of tumor necrosis factor α-resistant human melanoma by tumor-specific in vivo transfer of the gene encoding endothelial monocyte-activating polypeptide II using recombinant vaccinia virus Cancer Res 1999 59: 4668–4674 / Cancer Res by MFX Gnant (1999)
  19. Gnant MFX et al. Tumor-specific gene delivery using recombinant vaccinia virus in a rabbit model of liver metastases J Natl Cancer Inst 1999 91: 1744–1750 (10.1093/jnci/91.20.1744) / J Natl Cancer Inst by MFX Gnant (1999)
  20. Heise CC et al. Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy Cancer Res 1999 59: 2623–2628 / Cancer Res by CC Heise (1999)
  21. Ogris M et al. PEGylated DNA/transferring–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery Gene Therapy 1999 6: 595–605 (10.1038/sj.gt.3300900) / Gene Therapy by M Ogris (1999)
  22. Xu M et al. Gene therapy with p53 inhibits human breast tumors in vivo through a bystander mechanism without evidence of toxicity Hum Gene Ther 1997 8: 177–185 (10.1089/hum.1997.8.2-177) / Hum Gene Ther by M Xu (1997)
  23. Xu L et al. Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts Hum Gene Ther 1999 10: 2941–2952 (10.1089/10430349950016357) / Hum Gene Ther by L Xu (1999)
  24. Thurston G et al. Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice J Clin Invest 1998 101: 1401–1413 (10.1172/JCI965) / J Clin Invest by G Thurston (1998)
  25. Lasic DD et al. Sterically stabilized liposomes: a hypothesis on the molecular origin of the extended circulation times Biochim Biophys Acta 1991 1070: 187–192 (10.1016/0005-2736(91)90162-2) / Biochim Biophys Acta by DD Lasic (1991)
  26. Mok KWC, Lam AMI, Cullis PR . Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties Biochim Biophys Acta 1999 1419: 137–150 (10.1016/S0005-2736(99)00059-0) / Biochim Biophys Acta by KWC Mok (1999)
  27. Webb M et al. Comparison of hydrophobic anchors conjugated to poly(ethylene)glycol: effects on the pharmacokinetics on the liposomal vincristine Biochim Biophys Acta 1998 1372: 272–282 (10.1016/S0005-2736(98)00077-7) / Biochim Biophys Acta by M Webb (1998)
  28. Hope MJ et al. Generation of multilamellar and unilamellar phopholipid vesicles Chem Phys Lipids 1986 40: 89–107 (10.1016/0009-3084(86)90065-4) / Chem Phys Lipids by MJ Hope (1986)
  29. Bally MB, Mayer LD, Hope MJ, Nayar R . Pharmacodynamics of liposomal drug carriers: methodological considerations Liposome Technol 1993 18: 27–41 / Liposome Technol by MB Bally (1993)
Dates
Type When
Created 23 years ago (Sept. 4, 2002, 12:53 p.m.)
Deposited 2 years, 3 months ago (May 23, 2023, 1:30 p.m.)
Indexed 1 day, 18 hours ago (Sept. 4, 2025, 10:16 a.m.)
Issued 24 years, 10 months ago (Nov. 1, 2000)
Published 24 years, 10 months ago (Nov. 1, 2000)
Published Online 24 years, 10 months ago (Nov. 6, 2000)
Published Print 24 years, 10 months ago (Nov. 1, 2000)
Funders 0

None

@article{Tam_2000, title={Stabilized plasmid-lipid particles for systemic gene therapy}, volume={7}, ISSN={1476-5462}, url={http://dx.doi.org/10.1038/sj.gt.3301308}, DOI={10.1038/sj.gt.3301308}, number={21}, journal={Gene Therapy}, publisher={Springer Science and Business Media LLC}, author={Tam, P and Monck, M and Lee, D and Ludkovski, O and Leng, E C and Clow, K and Stark, H and Scherrer, P and Graham, R W and Cullis, P R}, year={2000}, month=nov, pages={1867–1874} }