DOI: 10.1038/sj.clpt.6100087. The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response

The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response

10.1038/sj.clpt.6100087

Crossref journal-article

Wiley

Clinical Pharmacology & Therapeutics (311)

Bibliography

Giacomini, K. M., Brett, C. M., Altman, R. B., Benowitz, N. L., Dolan, M. E., Flockhart, D. A., Johnson, J. A., Hayes, D. F., Klein, T., Krauss, R. M., Kroetz, D. L., McLeod, H. L., Nguyen, A. T., Ratain, M. J., Relling, M. V., Reus, V., Roden, D. M., Schaefer, C. A., Shuldiner, A. R., â¦ Zineh, I. (2007). The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response. Clinical Pharmacology & Therapeutics, 81(3), 328â345.

Authors 26

K M Giacomini (first)
C M Brett (additional)
R B Altman (additional)
N L Benowitz (additional)
M E Dolan (additional)
D A Flockhart (additional)
J A Johnson (additional)
D F Hayes (additional)
T Klein (additional)
R M Krauss (additional)
D L Kroetz (additional)
H L McLeod (additional)
A T Nguyen (additional)
M J Ratain (additional)
M V Relling (additional)
V Reus (additional)
D M Roden (additional)
C A Schaefer (additional)
A R Shuldiner (additional)
T Skaar (additional)
K Tantisira (additional)
R F Tyndale (additional)
L Wang (additional)
R M Weinshilboum (additional)
S T Weiss (additional)
I Zineh (additional)

References 104 Referenced 198

10.1038/sj.tpj.6500035 / Pharmacogenomics J. by Klein T.E. (2001)
10.1161/01.HYP.0000142248.54761.56
10.1001/jama.289.19.2560
10.1056/NEJM199304013281303
10.1016/S0895-7061(03)01011-2
10.1038/sj.tpj.6500215
10.1161/01.HYP.37.2.739 / Hypertension by Turner S.T. (2001)
10.1161/01.HYP.0000186240.81996.57
10.1016/S0009-9236(03)00068-7
10.1016/0895-7061(94)00250-F
10.1016/j.amjhyper.2004.10.021
10.1592/phco.26.9.1247
10.1016/j.amjcard.2005.09.134 / Am. J. Cardiol. by Simon J.A. (2006)
{'key': '6100087-bib14', 'first-page': '725', 'volume': '112', 'author': 'Krauss R.M.', 'year': '2005', 'journal-title': 'Circulation Supplement II'} / Circulation Supplement II by Krauss R.M. (2005)
10.1001/jama.291.23.2821
10.1161/hc4301.098254 / Circulation by Zheng Z.J. (2001)
10.1093/aje/155.9.819
10.1016/j.cardiores.2005.04.022
10.1056/NEJMra032426
10.1056/NEJM199711273372202 / N. Engl. J. Med. by Mcanulty J. (1997)
10.1056/NEJMoa013474
10.1056/NEJM198908103210629 / N. Engl. J. Med. (1989)
10.1038/32675
10.1161/01.RES.85.12.1206 / Circ. Res. by Bezzina C. (1999)
10.1016/j.cardiores.2003.09.030
{'key': '6100087-bib26', 'unstructured': ''}
10.1016/j.clpt.2004.10.008 / Clin. Pharmacol. Ther. by Simard C. (2005)
10.1172/JCI23741
10.1055/s-0037-1613290 / Thromb. Haemost. by McKee S.A. (2002)
10.1016/S0735-1097(02)03013-9
10.1016/S0735-1097(02)03014-0
10.1161/01.CIR.0000112378.09325.F9
10.1161/01.CIR.0000130846.46168.03
10.1161/01.CIR.0000072771.11429.83
10.1111/j.1398-9995.2004.00526.x
10.7326/0003-4819-130-6-199903160-00005 / Ann. Intern. Med. by Malmstrom K. (1999)
10.1067/mai.2002.122635
10.1258/0007142001903535
10.1093/hmg/ddh149
10.1073/pnas.0408532102
10.1093/hmg/ddi175
10.1164/rccm.200509-1412OC
10.1038/ng1582
10.1086/378591
10.1038/nrg1839
10.1186/1471-2156-6-S1-S115
10.1056/NEJM200010123431501 / N. Engl. J. Med. (2000)
10.1038/sj.tpj.6500387 / Pharmacogenomics J. by Weiss S.T. (2006)
10.1038/sj.mp.4001794 / Mol. Psychol by Malaiyandi V. (2006)
10.1016/j.clpt.2006.02.006
10.1016/j.clpt.2006.08.011 / Clin. Pharmacol. Ther. by Benowitz N.L. (2006)
10.1038/86882
10.1152/japplphysiol.00322.2003 / J. Appl. Physiol. by Givens R.C. (2003)
10.1086/426406
10.1097/00008571-200110000-00003
10.1016/S0169-409X(02)00066-2
10.1016/j.clpt.2005.11.013 / Clin. Pharmacol. Ther. by Lamba J. (2006)
10.1124/mol.58.4.863 / Mol. Pharmacol. by Lan L.B. (2000)
10.1038/sj.tpj.6500351
{'key': '6100087-bib60', 'first-page': '3723', 'volume': '54', 'author': 'Gupta E.', 'year': '1994', 'journal-title': 'Cancer Res.'} / Cancer Res. by Gupta E. (1994)
10.1007/s002800050595
10.1172/JCI915 / J. Clin. Invest. by Iyer L. (1998)
10.1038/sj.tpj.6500072
10.1200/JCO.2004.07.173
10.1158/0008-5472.CAN-04-0340
10.1056/NEJMoa040938
10.1126/science.1099314
10.1158/0008-5472.46.65.1 / Cancer Res. by Liu W. (2005)
{'key': '6100087-bib69', 'first-page': '1009', 'volume': '9', 'author': 'Liu W.', 'year': '2003', 'journal-title': 'Clin. Cancer Res.'} / Clin. Cancer Res. by Liu W. (2003)
10.1056/NEJMra023001
10.1182/blood-2004-11-4544
10.1200/JCO.2004.11.020
10.1182/blood-2005-08-3379
10.1093/hmg/ddi170
10.1038/ng1151
10.1056/NEJMoa033513
10.1016/j.ccr.2005.03.002
10.1038/ng1612
10.1093/jnci/djg108 / J. Nat. Cancer Inst. by Stearns V. (2003)
10.1124/jpet.104.065607
10.1023/B:BREA.0000025406.31193.e8
10.1124/jpet.105.100511
10.1093/jnci/dji005 / J. Natl. Cancer Inst. by Jin Y. (2005)
10.1200/JCO.2005.03.3266
10.1007/s10549-006-9428-0 / Breast Cancer Res. and Treat by Goetz M.P. (2007)
10.1002/path.1955
10.1093/hmg/ddi387
10.1158/1078-0432.CCR-06-0547
10.1007/s00424-003-1192-y
10.1146/annurev.biochem.71.102301.093055
10.1097/00008571-200308000-00006
10.1073/pnas.0730857100
10.1101/gr.4356206 / Genome Res. by Urban T.J. (2006)
10.1046/j.1471-4159.1996.66062621.x / J. Neurochem. by Heils A. (1996)
10.1097/01.ypg.0000218611.53064.a0
10.1038/sj.onc.1209372 / Oncogene Rev. by Wang L. (2006)
10.1016/j.clpt.2003.12.002
10.1097/01.fpc.0000174788.69991.6b / Pharmacogenet. Genomics by Salavaggione O.E. (2005)
10.1097/01.fpc.0000194423.20393.08 / Pharmacogenet. Genomics by Martin Y.N. (2006)
{'key': '6100087-bib100', 'unstructured': ''}
10.1073/pnas.94.12.6444
10.1097/00008571-200309000-00004
10.1073/pnas.0502352102
10.7326/0003-4819-145-10-200611210-00007 / Ann. Intern. Med. by Roden D.M. (2006)

Dates

Type	When
Created	18 years, 4 months ago (April 5, 2007, 5:45 a.m.)
Deposited	1 year, 9 months ago (Nov. 7, 2023, 8:19 a.m.)
Indexed	6 days, 9 hours ago (Aug. 26, 2025, 3:12 a.m.)
Issued	18 years, 6 months ago (March 1, 2007)
Published	18 years, 6 months ago (March 1, 2007)
Published Print	18 years, 6 months ago (March 1, 2007)

Funders 0

None

BibTeX

@article{Giacomini_2007, title={The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response}, volume={81}, ISSN={1532-6535}, url={http://dx.doi.org/10.1038/sj.clpt.6100087}, DOI={10.1038/sj.clpt.6100087}, number={3}, journal={Clinical Pharmacology & Therapeutics}, publisher={Wiley}, author={Giacomini, K M and Brett, C M and Altman, R B and Benowitz, N L and Dolan, M E and Flockhart, D A and Johnson, J A and Hayes, D F and Klein, T and Krauss, R M and Kroetz, D L and McLeod, H L and Nguyen, A T and Ratain, M J and Relling, M V and Reus, V and Roden, D M and Schaefer, C A and Shuldiner, A R and Skaar, T and Tantisira, K and Tyndale, R F and Wang, L and Weinshilboum, R M and Weiss, S T and Zineh, I}, year={2007}, month=mar, pages={328–345} }

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      "key": "6100087-bib11",
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      "volume": "15",
      "author": "Simon J.A.",
      "year": "2006",
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      "first-page": "725",
      "volume": "112",
      "author": "Krauss R.M.",
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      "DOI": "10.1161/hc4301.098254",
      "volume": "104",
      "author": "Zheng Z.J.",
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      "journal-title": "Circulation"
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      "DOI": "10.1093/aje/155.9.819"
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      "volume": "337",
      "author": "Mcanulty J.",
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      "key": "6100087-bib21",
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      "author": "Bezzina C.",
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    {
      "key": "6100087-bib25",
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      "DOI": "10.1016/j.clpt.2006.08.011",
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      "DOI": "10.1152/japplphysiol.00322.2003",
      "volume": "95",
      "author": "Givens R.C.",
      "year": "2003",
      "journal-title": "J. Appl. Physiol."
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      "first-page": "325",
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      "volume": "79",
      "author": "Lamba J.",
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      "journal-title": "Clin. Pharmacol. Ther."
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      "key": "6100087-bib58",
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      "DOI": "10.1124/mol.58.4.863",
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      "author": "Lan L.B.",
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    {
      "key": "6100087-bib59",
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      "key": "6100087-bib60",
      "first-page": "3723",
      "volume": "54",
      "author": "Gupta E.",
      "year": "1994",
      "journal-title": "Cancer Res."
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      "key": "6100087-bib61",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/s002800050595"
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      "DOI": "10.1172/JCI915",
      "volume": "101",
      "author": "Iyer L.",
      "year": "1998",
      "journal-title": "J. Clin. Invest."
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    {
      "key": "6100087-bib63",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/sj.tpj.6500072"
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      "key": "6100087-bib69",
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      "DOI": "10.1093/jnci/djg108",
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      "key": "6100087-bib84",
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