DOI: 10.1038/sj.cdd.4400769. Quantitative analysis of fluorescent caspase substrate cleavage in intact cells and identification of novel inhibitors of apoptosis

Quantitative analysis of fluorescent caspase substrate cleavage in intact cells and identification of novel inhibitors of apoptosis

10.1038/sj.cdd.4400769

Crossref journal-article

Springer Science and Business Media LLC

Cell Death & Differentiation (297)

Bibliography

Tawa, P., Tam, J., Cassady, R., Nicholson, D. W., & Xanthoudakis, S. (2001). Quantitative analysis of fluorescent caspase substrate cleavage in intact cells and identification of novel inhibitors of apoptosis. Cell Death & Differentiation, 8(1), 30â37.

Authors 5

P Tawa (first)
J Tam (additional)
R Cassady (additional)
D W Nicholson (additional)
S Xanthoudakis (additional)

References 30 Referenced 49

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Vaux DL, Haecker G and Strasser A . 1994 An evolutionary perspective on apoptosis Cell 76: 777–779 (10.1016/0092-8674(94)90350-6) / Cell by DL Vaux (1994)
Steller H . 1995 Mechanisms and genes of cellular suicide Science 267: 1445–1449 (10.1126/science.7878463) / Science by H Steller (1995)
Thornberry NA and Lazebnik Y . 1998 Caspases: enemies within Science 281: 1312–1316 (10.1126/science.281.5381.1312) / Science by NA Thornberry (1998)
Thornberry NA . 1997 The caspase family of cysteine proteases Br. Med. Bull. 53: 478–490 (10.1093/oxfordjournals.bmb.a011625) / Br. Med. Bull. by NA Thornberry (1997)
Nicholson DW and Thornberry NA . 1997 Caspases: killer proteases Trends Biochem. Sci. 22: 299–306 (10.1016/S0968-0004(97)01085-2) / Trends Biochem. Sci. by DW Nicholson (1997)
Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT and Nicholson DW . 1997 A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis J. Biol. Chem. 272: 17907–17911 (10.1074/jbc.272.29.17907) / J. Biol. Chem. by NA Thornberry (1997)
Hirata H, Takahashi A, Kobayashi S, Yonehara S, Sawai H, Okazaki T, Yamamoto K and Sasada M . 1998 Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis J. Exp. Med. 187: 587–600 (10.1084/jem.187.4.587) / J. Exp. Med. by H Hirata (1998)
Kawahara A, Enari M, Talanian RV, Wong WW and Nagata S . 1998 Fas-induced DNA fragmentation and proteolysis of nuclear proteins Genes Cells 3: 297–306 (10.1046/j.1365-2443.1998.00189.x) / Genes Cells by A Kawahara (1998)
Nicholson DW . 1996 ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis Nat. Biotechnol. 14: 297–301 (10.1038/nbt0396-297) / Nat. Biotechnol. by DW Nicholson (1996)
Darzynkiewicz Z and Traganos F . 1998 Measurement of apoptosis Adv. Biochem. Eng. Biotechnol. 62: 33–73 / Adv. Biochem. Eng. Biotechnol. by Z Darzynkiewicz (1998)
Misteli T and Spector DL . 1997 Applications of the green fluorescent protein in cell biology and biotechnology Nat. Biotechnol. 15: 961–964 (10.1038/nbt1097-961) / Nat. Biotechnol. by T Misteli (1997)
Tsien RY . 1998 The green fluorescent protein Annu. Rev. Biochem. 67: 509–544 (10.1146/annurev.biochem.67.1.509) / Annu. Rev. Biochem. by RY Tsien (1998)
Pollok BA and Heim R . 1999 Using GFP in FRET-based applications [In Process Citation] Trends Cell. Biol. 9: 57–60 (10.1016/S0962-8924(98)01434-2) / Trends Cell. Biol. by BA Pollok (1999)
Mitra RD, Silva CM and Youvan DC . 1996 Fluorescence resonance energy transfer between blue-emitting and red-shifted excitation derivatives of the green fluorescent protein Gene 173: 13–17 (10.1016/0378-1119(95)00768-7) / Gene by RD Mitra (1996)
Heim R and Tsien RY . 1996 Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer Curr. Biol. 6: 178–182 (10.1016/S0960-9822(02)00450-5) / Curr. Biol. by R Heim (1996)
Xu X, Gerard AL, Huang BC, Anderson DC, Payan DG and Luo Y . 1998 Detection of programmed cell death using fluorescence energy transfer Nucleic Acids Res. 26: 2034–2035 (10.1093/nar/26.8.2034) / Nucleic Acids Res. by X Xu (1998)
Mahajan NP, Harrison-Shostak DC, Michaux J and Herman B . 1999 Novel mutant green fluorescent protein protease substrates reveal the activation of specific caspases during apoptosis Chem. Biol. 6: 401–409 (10.1016/S1074-5521(99)80051-9) / Chem. Biol. by NP Mahajan (1999)
Gossen M, Bonin AL, Freundlieb S and Bujard H . 1994 Inducible gene expression systems for higher eukaryotic cells Curr. Opin. Biotechnol. 5: 516–520 (10.1016/0958-1669(94)90067-1) / Curr. Opin. Biotechnol. by M Gossen (1994)
Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG and Earnshaw WC . 1994 Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE Nature 371: 346–347 (10.1038/371346a0) / Nature by YA Lazebnik (1994)
Hall JC . 1998 Glycine JPEN J. Parenter. Enteral. Nutr. 22: 393–398 (10.1177/0148607198022006393) / JPEN J. Parenter. Enteral. Nutr. by JC Hall (1998)
Freund C, Ross A, Guth B, Pluckthun A and Holak TA . 1993 Characterization of the linker peptide of the single-chain Fv fragment of an antibody by NMR spectroscopy FEBS Lett. 320: 97–100 (10.1016/0014-5793(93)80070-B) / FEBS Lett. by C Freund (1993)
Steinert PM, Mack JW, Korge BP, Gan SQ, Haynes SR and Steven AC . 1991 Glycine loops in proteins: their occurrence in certain intermediate filament chains, loricrins and single-stranded RNA binding proteins Int. J. Biol. Macromol. 13: 130–139 (10.1016/0141-8130(91)90037-U) / Int. J. Biol. Macromol. by PM Steinert (1991)
Casciola-Rosen L, Nicholson DW, Chong T, Rowan KR, Thornberry NA, Miller DK and Rosen A . 1996 Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death [see comments] J. Exp. Med. 183: 1957–1964 (10.1084/jem.183.5.1957) / J. Exp. Med. by L Casciola-Rosen (1996)
Bossy-Wetzel E, Newmeyer DD and Green DR . 1998 Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization EMBO J. 17: 37–49 (10.1093/emboj/17.1.37) / EMBO J. by E Bossy-Wetzel (1998)
Janicke RU, Ng P, Sprengart ML and Porter AG . 1998 Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis J. Biol. Chem. 273: 15540–15545 (10.1074/jbc.273.25.15540) / J. Biol. Chem. by RU Janicke (1998)
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Rasper DM, Vaillancourt JP, Hadano S, Houtzager VM, Seiden I, Keen SLC, Tawa P, Xanthoudakis S, Nasir J, Martindale D, Koop BF, Peterson EP, Thornberry NA, Huang J, Black SC, Hornung F, Leonardo MJ, Hayden M, Roy S and Nicholson DW . 1998 Cell death attenuation by ‘Usurpin’, a mammalian DED-caspase homologue that precludes Caspase-8 recruitment and activation by the CD-95 receptor complex Cell Death Differ. 5: 271–288 (10.1038/sj.cdd.4400370) / Cell Death Differ. by DM Rasper (1998)
Garcia-Calvo M, Peterson EP, Leiting B, Ruel R, Nicholson DW and Thornberry NA . 1998 Inhibition of human caspases by peptide-based and macromolecular inhibitors J. Biol. Chem. 273: 32608–32613 (10.1074/jbc.273.49.32608) / J. Biol. Chem. by M Garcia-Calvo (1998)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 17, 2002, 1:35 p.m.)
Deposited	2 years, 3 months ago (May 17, 2023, 8:16 p.m.)
Indexed	1 year, 2 months ago (June 4, 2024, 3:14 a.m.)
Issued	24 years, 7 months ago (Jan. 1, 2001)
Published	24 years, 7 months ago (Jan. 1, 2001)
Published Online	24 years, 5 months ago (March 15, 2001)
Published Print	24 years, 7 months ago (Jan. 1, 2001)

Funders 0

None

BibTeX

@article{Tawa_2001, title={Quantitative analysis of fluorescent caspase substrate cleavage in intact cells and identification of novel inhibitors of apoptosis}, volume={8}, ISSN={1476-5403}, url={http://dx.doi.org/10.1038/sj.cdd.4400769}, DOI={10.1038/sj.cdd.4400769}, number={1}, journal={Cell Death & Differentiation}, publisher={Springer Science and Business Media LLC}, author={Tawa, P and Tam, J and Cassady, R and Nicholson, D W and Xanthoudakis, S}, year={2001}, month=jan, pages={30–37} }

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