DOI: 10.1038/sj.bjc.6690679. Proteolytic cleavage of p53 mutants in response to mismatched DNA

Proteolytic cleavage of p53 mutants in response to mismatched DNA

10.1038/sj.bjc.6690679

Crossref journal-article

Springer Science and Business Media LLC

British Journal of Cancer (297)

Bibliography

Mee, T., Okorokov, A. L., Metcalfe, S., & Milner, J. (1999). Proteolytic cleavage of p53 mutants in response to mismatched DNA. British Journal of Cancer, 81(2), 212â218.

Authors 4

T Mee (first)
A L Okorokov (additional)
S Metcalfe (additional)
J Milner (additional)

References 25 Referenced 6

Caelles, C, Helmberg, A & Karin, M (1994). p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370: 220–223. (10.1038/370220a0) / Nature by C Caelles (1994)
Cho, Y, Gorina, S, Jeffrey, PD & Pavletich, NP (1994). Crystal structure of a p53 tumor suppressor–DNA complex: understanding tumorigenic mutations. Science 265: 346–355. (10.1126/science.8023157) / Science by Y Cho (1994)
El-Diery, WS, Tokino, T, Velculescu, VE, Levy, DB, Parsons, R, Trent, JM, Lin, D, Mercer, WE, Kinzler, KW & Vogelstein, B (1993). WAF1, a potential mediator of p53 tumour suppression. Cell 75: 817–825. (10.1016/0092-8674(93)90500-P) / Cell by WS El-Diery (1993)
Funk, WD, Pak, DJ, Karas, RH, Wright, WE & Shay, JW (1992). A transcriptionally active DNA-binding site for human p53 protein complexes. Mol Cell Biol 12: 2866–2871. (10.1128/MCB.12.6.2866) / Mol Cell Biol by WD Funk (1992)
Gannon, JV, Greaves, R, Iggo, R & Lane, DP (1990). Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J 9: 1595–1602. (10.1002/j.1460-2075.1990.tb08279.x) / EMBO J by JV Gannon (1990)
Gorina, S & Pavletich, NP (1996). Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science 274: 1001–1005. (10.1126/science.274.5289.1001) / Science by S Gorina (1996)
Gottlieb, TM & Oren, M (1996). p53 in growth control and neoplasia. Biochim Biophys Acta 1287: 77–102. / Biochim Biophys Acta by TM Gottlieb (1996)
Haupt, Y & Oren, M (1996). p53-mediated apoptosis: mechanisms and regulation. Behring Inst Mitt 97: 32–59. / Behring Inst Mitt by Y Haupt (1996)
Haupt, Y, Rowan, S, Shaulian, E, Vousden, KH & Oren, M (1995). Induction of apoptosis in HeLa cells by transactivation-deficient p53. Genes Dev 9: 2170–2183. (10.1101/gad.9.17.2170) / Genes Dev by Y Haupt (1995)
Jayaraman, J & Prives, C (1995). Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell 81: 1021–1029. (10.1016/S0092-8674(05)80007-8) / Cell by J Jayaraman (1995)
Ko, LJ & Prives, C (1996). p53: puzzle and paradigm. Genes Dev 10: 1054–1072. (10.1101/gad.10.9.1054) / Genes Dev by LJ Ko (1996)
Lee, S, Elenbaas, B, Levine, A & Griffith, J (1995). p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches. Cell 81: 1013–1020. (10.1016/S0092-8674(05)80006-6) / Cell by S Lee (1995)
Levine, AJ (1997). p53, the cellular gatekeeper for growth and division. Cell 88: 323–331. (10.1016/S0092-8674(00)81871-1) / Cell by AJ Levine (1997)
Meek, DW (1994). Post-translational modification of p53. Semin Cancer Biol 5: 203–210. / Semin Cancer Biol by DW Meek (1994)
Michalovitz, D, Halevy, O & Oren, M (1990). Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62: 671–680. (10.1016/0092-8674(90)90113-S) / Cell by D Michalovitz (1990)
Milne, DM, McKendrick, L, Jardine, LJ, Deacon, E, Lord, JM & Meek, DW (1996). Murine p53 is phosphorylated within the PAb421 epitope by protein kinase C in vitro, but not in vivo, even after stimulation with the phorbol ester o-tetradecanoylphorbol 13-acetate. Oncogene 13: 205–211. / Oncogene by DM Milne (1996)
Milner, J, Metcalf, EA & Cook, A (1991). Tumour suppressor p53: analysis of wild-type and mutant p53 complexes. Mol Cell Biol 11: 12–19. (10.1128/MCB.11.1.12) / Mol Cell Biol by J Milner (1991)
Miyashita, T & Reed, JC (1995). Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293–299. (10.1016/0092-8674(95)90513-8) / Cell by T Miyashita (1995)
Molinari, M, Okorokov, AL & Milner, J (1996). Interaction with damaged DNA induces selective proteolytic cleavage of p53 to yield 40-kDa and 35-kDa fragments competent for sequence-specific DNA binding. Oncogene 13: 2077–2086. / Oncogene by M Molinari (1996)
Mummenbrauer, T, Janus, F, Muller, B, Wiesmuller, L, Deppert, W & Grosse, F (1996). p53 Protein exhibits 3′-to-5′ exonuclease activity. Cell 85: 1089–1099. (10.1016/S0092-8674(00)81309-4) / Cell by T Mummenbrauer (1996)
Okorokov, AL, Ponchel, F & Milner, J (1997). Induced N- and C- terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53. EMBO J 16: 6008–6017. (10.1093/emboj/16.19.6008) / EMBO J by AL Okorokov (1997)
Paetzel, M & Dalbey, RE (1997). Catalytic hydroxyl/amine dyads within serine proteases. Trends Biochem Sci 22: 28–31. (10.1016/S0968-0004(96)10065-7) / Trends Biochem Sci by M Paetzel (1997)
Steegenga, WT, van der Eb, AJ & Jochemsen, AG (1996). How phosphorylation regulates the activity of p53. J Mol Biol 263: 103–113. (10.1006/jmbi.1996.0560) / J Mol Biol by WT Steegenga (1996)
Takenaka, I, Morin, F, Seizinger, BR & Kley, N (1995). Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases. J Biol Chem 270: 5405–5411. (10.1074/jbc.270.10.5405) / J Biol Chem by I Takenaka (1995)
Thukral, SK, Blain, GC, Chang, KK & Fields, S (1994). Distinct residues of human p53 implicated in binding to DNA, simian virus 40 large T antigen, 53BP1, and 53BP2. Mol Cell Biol 14: 8315–8321. (10.1128/MCB.14.12.8315) / Mol Cell Biol by SK Thukral (1994)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 5, 2002, 2:09 p.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 8:55 a.m.)
Indexed	1 year, 10 months ago (Oct. 16, 2023, 1:53 a.m.)
Issued	26 years ago (Aug. 27, 1999)
Published	26 years ago (Aug. 27, 1999)
Published Online	26 years ago (Aug. 27, 1999)
Published Print	25 years, 11 months ago (Sept. 1, 1999)

Funders 0

None

BibTeX

@article{Mee_1999, title={Proteolytic cleavage of p53 mutants in response to mismatched DNA}, volume={81}, ISSN={1532-1827}, url={http://dx.doi.org/10.1038/sj.bjc.6690679}, DOI={10.1038/sj.bjc.6690679}, number={2}, journal={British Journal of Cancer}, publisher={Springer Science and Business Media LLC}, author={Mee, T and Okorokov, A L and Metcalfe, S and Milner, J}, year={1999}, month=aug, pages={212–218} }

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