Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells
10.1038/sj.bjc.6690176
Crossref journal-article
Springer Science and Business Media LLC
British Journal of Cancer (297)
Bibliography

Nehmé, A., Baskaran, R., Nebel, S., Fink, D., Howell, S. B., Wang, J. Y. J., & Christen, R. D. (1999). Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells. British Journal of Cancer, 79(7–8), 1104–1110.

Authors 7
  1. A Nehmé (first)
  2. R Baskaran (additional)
  3. S Nebel (additional)
  4. D Fink (additional)
  5. S B Howell (additional)
  6. J Y J Wang (additional)
  7. R D Christen (additional)
References 43 Referenced 89
  1. Aebi, S., Kurdi-Haidar, B., Gordon, R., Cenni, B., Zheng, H., Fink, D., Christen, R. D., Boland, C. R., Koi, M., Fishel, R. & Howell, S. B. (1996). Loss of DNA mismatch repair in acquired resistance to cisplatin. Cancer Res 56: 3087–3090. / Cancer Res by S Aebi (1996)
  2. Aebi, S., Fink, D., Gordon, R., Kim, H. K., Zheng, H., Fink, J. L. & Howell, S. B. (1997). Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells. Clin Cancer Res 3: 1763–1767. / Clin Cancer Res by S Aebi (1997)
  3. Baskaran, R., Chiang, G. G. & Wang, J. Y. J. (1996). Identification of a binding site in c-Abl tyrosine kinase for the C-terminal repeated domain of RNA polymerase II. Mol Cell Biol 16: 3361–3369. (10.1128/MCB.16.7.3361) / Mol Cell Biol by R Baskaran (1996)
  4. Baskaran, R., Wood, L. D., Whitaker, L. L., Canman, C. E., Morgan, S. E., Xu, Y., Barlow, C., Baltimore, D., Wynshaw-Boris, A., Kastan, M. B. & Wang, J. Y. J. (1997). Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature 387: 516–519. (10.1038/387516a0) / Nature by R Baskaran (1997)
  5. Cavigelli, M., Dolfi, F., Claret, F. X. & Karin, M. (1995). Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation. EMBO J 14: 5957–5964. (10.1002/j.1460-2075.1995.tb00284.x) / EMBO J by M Cavigelli (1995)
  6. Chaney, S. G. (1995). The chemistry and biology of platinum complexes with the 1,2-diaminocyclohexane carrier ligand. Int J Oncol 6: 1291–1305. / Int J Oncol by SG Chaney (1995)
  7. Chen, Z., Naito, M., Mashima, T. & Tsuruo, T. (1996). Activation of actin-cleavable interleukin 1-converting enzyme (ICE) family protease CCP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells. Cancer Res 56: 5224–5229. / Cancer Res by Z Chen (1996)
  8. Christian, M. C. (1992). The current status of new platinum analogs. Semin Oncol 19: 720–733. / Semin Oncol by MC Christian (1992)
  9. Derijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M. & Davis, R. J. (1994). JNK1: a protein kinase stimulated by UV light and Ha-ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025–1037. (10.1016/0092-8674(94)90380-8) / Cell by B Derijard (1994)
  10. Derijard, B., Raingeaud, J., Barrett, T., Wu, I. H., Han, J., Ulevitch, R. J. & Davis, R. J. (1995). Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267: 682–685. (10.1126/science.7839144) / Science by B Derijard (1995)
  11. Duckett, D. R., Drummond, J. T., Murchie, A. I. H., Readon, J. T., Sancar, A., Lilley, D. M. J. & Modrich, P. (1996). Human MutSα recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci USA 93: 6443–6447. (10.1073/pnas.93.13.6443) / Proc Natl Acad Sci USA by DR Duckett (1996)
  12. Eastman, A. (1990). Activation of programmed cell death by anticancer agents: cisplatin as a model system. Cancer Cells 2: 275–280. / Cancer Cells by A Eastman (1990)
  13. Fink, D., Nebel, S., Aebi, S., Zheng, H., Cenni, B., Nehmé, A., Christen, R. D. & Howell, S. B. (1996). The role of DNA mismatch repair in platinum drug resistance. Cancer Res 56: 4881–4886. / Cancer Res by D Fink (1996)
  14. Fink, D., Zheng, H., Nebel, S., Norris, P. S., Aebi, S., Lin, T-P, Nehmé, A., Christen, R. D., Haas, M., Macleod, C. L. & Howell, S. B. (1997). In vitro and In vivo resistance to cisplatin in cells that have lost DNA mismatch repair. Cancer Res 53: 1841–1845. / Cancer Res by D Fink (1997)
  15. Fishel, R. & Wilson, T. (1997). MutS homologs in mammalian cells. Curr Opin Genet Dev 7: 105–113. (10.1016/S0959-437X(97)80117-7) / Curr Opin Genet Dev by R Fishel (1997)
  16. Gupta, S., Campbell, D., Derijard, B. & Davis, R. J. (1995). Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267: 389–393. (10.1126/science.7824938) / Science by S Gupta (1995)
  17. Hawn, M. T., Umar, A., Carethers, J. M., Marra, G., Kunkel, T. A., Boland, C. R. & Koi, M. (1995). Evidence for a connection between the mismatch repair system and the G2cell cycle checkpoint. Cancer Res 55: 3721–3725. / Cancer Res by MT Hawn (1995)
  18. Hibi, M., Lin, A., Smeal, T., Minden, A. & Karin, M. (1993). Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 7: 2135–2148. (10.1101/gad.7.11.2135) / Genes Dev by M Hibi (1993)
  19. Kat, A., Thilly, W. G., Fang, W., Longley, M. J., Li, G. & Modrich, P. (1995). An alkylation–toleration, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci USA 90: 6424–6428. (10.1073/pnas.90.14.6424) / Proc Natl Acad Sci USA by A Kat (1995)
  20. Kelland, L. R. (1993). New platinum antitumor complexes. Crit Rev Oncol Hematol 15: 191–219. (10.1016/1040-8428(93)90042-3) / Crit Rev Oncol Hematol by LR Kelland (1993)
  21. Kharbanda, S., Ren, R., Pandey, P., Shafman, T. D., Feller, S. M., Weichselbaum, R. R. & Kufe, D. W. (1995). Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature 376: 785–788. (10.1038/376785a0) / Nature by S Kharbanda (1995)
  22. Kharbanda, S., Pandey, P., Jin, S., Inoue, S., Bharti, A., Yan, Z-M, Weicheselbaum, R., Weaver, D. & Kufe, D. (1997). Functional interaction between DNA-PK and c-Abl in response to DNA damage. Nature 386: 732–735. (10.1038/386732a0) / Nature by S Kharbanda (1997)
  23. Kipreos, E. T. & Wang, J. Y. J. (1992). Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA. Science 256: 382–385. (10.1126/science.256.5055.382) / Science by ET Kipreos (1992)
  24. Koi, M., Umar, A., Chauhan, D. P., Cherian, S. P., Carethers, J. M., Kunkel, T. A. & Boland, C. R. (1994). Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reducesN-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res 54: 4308–4312. / Cancer Res by M Koi (1994)
  25. Kolodner, R. (1996). Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 10: 1433–1442. (10.1101/gad.10.12.1433) / Genes Dev by R Kolodner (1996)
  26. Liu, Z-G, Baskaran, R., Lea-Chou, E. T., Wood, L. D., Chen, Y., Karin, M. & Wang, J. Y. J. (1996a). Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature 384: 273–276. (10.1038/384273a0) / Nature by Z-G Liu (1996)
  27. Liu, Z-G, Hsu, H., Goeddel, D. V. & Karin, M. (1996b). Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kB activation prevents cell death. Cell 87: 565–576. (10.1016/S0092-8674(00)81375-6) / Cell by Z-G Liu (1996)
  28. Los, G., Mutsaers, P. H., Ruevekamp, M. & McVie, J. G. (1990). The use of oxaliplatin versus cisplatin in intraperitoneal chemotherapy in cancers restricted to the peritoneal cavity in the rat. Cancer Lett 51: 109–117. (10.1016/0304-3835(90)90045-Y) / Cancer Lett by G Los (1990)
  29. Mattioni, T., Jackson, P. K., van Huijsduijnen, OB-H & Picard, D. (1995). Cell cycle arrest by tyrosine kinase Abl involves altered early mitogenic response. Oncogene 10: 1325–1333. / Oncogene by T Mattioni (1995)
  30. Mello, J. A., Acharya, S., Fishel, R. & Essigmann, J. M. (1996). The mismatch-repair protein hMSH2 binds selectivity to DNA adducts of the anticancer drug cisplatin. Chem Biol 3: 579–589. (10.1016/S1074-5521(96)90149-0) / Chem Biol by JA Mello (1996)
  31. Monks, A., Scudiero, D., Skehan, P., Shoemaker, R., Paull, K., Vistica, D., Hose, C., Langley, J., Cronise, P., Vaigro-Wolff, A., Gray-Woodrich, M., Campbell, H., Mayo, J. & Boyd, M. (1991). Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J Natl Cancer Inst 83: 757–766. (10.1093/jnci/83.11.757) / J Natl Cancer Inst by A Monks (1991)
  32. Nehme, A., Rajasekaran, B., Aebi, S., Fink, D., Nebel, S., Cenni, B., Wang, J. Y. J., Howell, S. B. & Christen, R. D. (1997). Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin. Cancer Res 57: 3253–3257. / Cancer Res by A Nehme (1997)
  33. Orth, K., Hung, J., Gazdar, A., Bowcock, A., Mathis, J. M. & Sambrook, J. (1994). Genetic instability in human ovarian cancer cell lines. Proc Natl Acad Sci USA 91: 9495–9499. (10.1073/pnas.91.20.9495) / Proc Natl Acad Sci USA by K Orth (1994)
  34. Saris, C. P., van de Vaart, P. J. M., Rietbroek, R. C. & Blommaert, F. A. (1996). In vitroformation of DNA adducts by cisplatin, lobaplatin and oxaliplatin in calf thymus DNA in solution and in cultured human cells. Carcinogenesis 17: 2763–2769. (10.1093/carcin/17.12.2763) / Carcinogenesis by CP Saris (1996)
  35. Sawyers, C. L., McLaughlin, J., Goga, A., Havlik, M. & Witte, O. (1994). The nuclear tyrosine kinase c-abl negatively regulates cell growth. Cell 77: 121–131. (10.1016/0092-8674(94)90240-2) / Cell by CL Sawyers (1994)
  36. Schmidt, W. & Chaney, S. G. (1993). Role of carrier ligand in platinum resistance of human carcinoma cell lines. Cancer Res 53: 799–805. / Cancer Res by W Schmidt (1993)
  37. Shafman, T., Khanna, K. K., Kedar, P., Spring, K., Kozlov, S., Yen, T., Hobson, K., Gatei, M., Zhang, N., Watters, D., Egerton, M., Shiloh, Y., Kharbanda, S., Kufe, D. & Lavin, M. F. (1997). Interaction between ATM protein and c-Abl in response to DNA damage. Nature 387: 520–523. (10.1038/387520a0) / Nature by T Shafman (1997)
  38. Skehan, P., Storeng, R., Scudiero, D., Monks, A., Mcmahon, J., Vistica, D., Warren, J. T., Bokesch, H., Kenney, S. & Boyd, M. R. (1990). New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107–1112. (10.1093/jnci/82.13.1107) / J Natl Cancer Inst by P Skehan (1990)
  39. Umar, A., Boyer, J. C., Thomas, D. C., Nguyen, D. C., Risinger, J. I., Boyd, J., Ionov, Y., Perucho, M. & Kunkel, T. A. (1994). Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J Biol Chem 269: 14367–14370. (10.1016/S0021-9258(17)36630-9) / J Biol Chem by A Umar (1994)
  40. Umar, A., Koi, M., Risinger, J. I., Glaab, W., Tindall, K. R., Kolodner, R., Boland, C. R., Barrett, J. C. & Kunkel, T. A. (1997). Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine-resistance and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res 57: 3949–4955. / Cancer Res by A Umar (1997)
  41. Wang, J. Y. J. (1993). Abl tyrosine kinase in signal transduction and cell-cycle regulation. Curr Opin Genet Dev 3: 35–43. (10.1016/S0959-437X(05)80338-7) / Curr Opin Genet Dev by JYJ Wang (1993)
  42. Woynarowski, J. M., Chapman, W. G., Napier, C. & Raymond, E. (1997). Oxaliplatin effects on naked and intracellular DNA. Proc Am Assoc Cancer Res 38: 311 / Proc Am Assoc Cancer Res by JM Woynarowski (1997)
  43. Yuan, Z. M., Huang, Y., Ishiko, T., Kharbanda, S., Weichselbaum, R. & Kufe, D. (1997). Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci USA 94: 1437–1440. (10.1073/pnas.94.4.1437) / Proc Natl Acad Sci USA by ZM Yuan (1997)
Dates
Type When
Created 22 years, 11 months ago (Sept. 17, 2002, 10:03 a.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 8:51 a.m.)
Indexed 1 year, 2 months ago (June 12, 2024, 9:18 a.m.)
Issued 26 years, 6 months ago (Feb. 12, 1999)
Published 26 years, 6 months ago (Feb. 12, 1999)
Published Online 26 years, 6 months ago (Feb. 12, 1999)
Published Print 26 years, 6 months ago (March 1, 1999)
Funders 0

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@article{Nehm__1999, title={Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells}, volume={79}, ISSN={1532-1827}, url={http://dx.doi.org/10.1038/sj.bjc.6690176}, DOI={10.1038/sj.bjc.6690176}, number={7–8}, journal={British Journal of Cancer}, publisher={Springer Science and Business Media LLC}, author={Nehmé, A and Baskaran, R and Nebel, S and Fink, D and Howell, S B and Wang, J Y J and Christen, R D}, year={1999}, month=feb, pages={1104–1110} }