Mechanism of transcriptional stalling at cisplatin-damaged DNA
10.1038/nsmb1314
Crossref journal-article
Springer Science and Business Media LLC
Nature Structural & Molecular Biology (297)
Bibliography

Damsma, G. E., Alt, A., Brueckner, F., Carell, T., & Cramer, P. (2007). Mechanism of transcriptional stalling at cisplatin-damaged DNA. Nature Structural & Molecular Biology, 14(12), 1127–1133.

Authors 5
  1. Gerke E Damsma (first)
  2. Aaron Alt (additional)
  3. Florian Brueckner (additional)
  4. Thomas Carell (additional)
  5. Patrick Cramer (additional)
References 27 Referenced 147
  1. Wang, D. & Lippard, S.J. Cellular processing of platinum anticancer drugs. Nat. Rev. Drug Discov. 4, 307–320 (2005). (10.1038/nrd1691) / Nat. Rev. Drug Discov. by D Wang (2005)
  2. Kartalou, M. & Essigmann, J.M. Recognition of cisplatin adducts by cellular proteins. Mutat. Res. 478, 1–21 (2001). (10.1016/S0027-5107(01)00142-7) / Mutat. Res. by M Kartalou (2001)
  3. Jung, Y. & Lippard, S.J. Multiple states of stalled T7 RNA polymerase at DNA lesions generated by platinum anticancer agents. J. Biol. Chem. 278, 52084–52092 (2003). (10.1074/jbc.M310120200) / J. Biol. Chem. by Y Jung (2003)
  4. Corda, Y., Job, C., Anin, M.F., Leng, M. & Job, D. Transcription by eucaryotic and procaryotic RNA polymerases of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II). Biochemistry 30, 222–230 (1991). (10.1021/bi00215a032) / Biochemistry by Y Corda (1991)
  5. Corda, Y., Job, C., Anin, M.F., Leng, M. & Job, D. Spectrum of DNA-platinum adduct recognition by prokaryotic and eukaryotic DNA-dependent RNA polymerases. Biochemistry 32, 8582–8588 (1993). (10.1021/bi00084a027) / Biochemistry by Y Corda (1993)
  6. Tornaletti, S., Patrick, S.M., Turchi, J.J. & Hanawalt, P.C. Behavior of T7 RNA polymerase and mammalian RNA polymerase II at site-specific cisplatin adducts in the template DNA. J. Biol. Chem. 278, 35791–35797 (2003). (10.1074/jbc.M305394200) / J. Biol. Chem. by S Tornaletti (2003)
  7. Jung, Y. & Lippard, S.J. RNA polymerase II blockage by cisplatin-damaged DNA. Stability and polyubiquitylation of stalled polymerase. J. Biol. Chem. 281, 1361–1370 (2006). (10.1074/jbc.M509688200) / J. Biol. Chem. by Y Jung (2006)
  8. Brueckner, F., Hennecke, U., Carell, T. & Cramer, P. CPD damage recognition by transcribing RNA polymerase II. Science 315, 859–862 (2007). (10.1126/science.1135400) / Science by F Brueckner (2007)
  9. Kettenberger, H., Armache, K.-J. & Cramer, P. Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol. Cell 16, 955–965 (2004). (10.1016/j.molcel.2004.11.040) / Mol. Cell by H Kettenberger (2004)
  10. Gelasco, A. & Lippard, S.J. NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin. Biochemistry 37, 9230–9239 (1998). (10.1021/bi973176v) / Biochemistry by A Gelasco (1998)
  11. Takahara, P.M., Rosenzweig, A.C., Frederick, C.A. & Lippard, S.J. Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin. Nature 377, 649–652 (1995). (10.1038/377649a0) / Nature by PM Takahara (1995)
  12. Kashkina, E. et al. Template misalignment in multisubunit RNA polymerases and transcription fidelity. Mol. Cell 24, 257–266 (2006). (10.1016/j.molcel.2006.10.001) / Mol. Cell by E Kashkina (2006)
  13. Gnatt, A.L., Cramer, P., Fu, J., Bushnell, D.A. & Kornberg, R.D. Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 Å resolution. Science 292, 1876–1882 (2001). (10.1126/science.1059495) / Science by AL Gnatt (2001)
  14. Strauss, B.S. The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions? Bioessays 13, 79–84 (1991). (10.1002/bies.950130206) / Bioessays by BS Strauss (1991)
  15. Taylor, J.S. New structural and mechanistic insight into the A-rule and the instructional and non-instructional behavior of DNA photoproducts and other lesions. Mutat. Res. 510, 55–70 (2002). (10.1016/S0027-5107(02)00252-X) / Mutat. Res. by JS Taylor (2002)
  16. Wind, M. & Reines, D. Transcription elongation factor SII. Bioessays 22, 327–336 (2000). (10.1002/(SICI)1521-1878(200004)22:4<327::AID-BIES3>3.0.CO;2-4) / Bioessays by M Wind (2000)
  17. Thomas, M.J., Platas, A.A. & Hawley, D.K. Transcriptional fidelity and proofreading by RNA polymerase II. Cell 93, 627–637 (1998). (10.1016/S0092-8674(00)81191-5) / Cell by MJ Thomas (1998)
  18. Tremeau-Bravard, A., Riedl, T., Egly, J.M. & Dahmus, M.E. Fate of RNA polymerase II stalled at a cisplatin lesion. J. Biol. Chem. 279, 7751–7759 (2004). (10.1074/jbc.M309853200) / J. Biol. Chem. by A Tremeau-Bravard (2004)
  19. Laine, J.P. & Egly, J.M. Initiation of DNA repair mediated by a stalled RNA polymerase IIO. EMBO J. 25, 387–397 (2006). (10.1038/sj.emboj.7600933) / EMBO J. by JP Laine (2006)
  20. Armache, K.-J., Kettenberger, H. & Cramer, P. Architecture of the initiation-competent 12-subunit RNA polymerase II. Proc. Natl. Acad. Sci. USA 100, 6964–6968 (2003). (10.1073/pnas.1030608100) / Proc. Natl. Acad. Sci. USA by K-J Armache (2003)
  21. Kabsch, W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Cryst. 26, 795–800 (1993). (10.1107/S0021889893005588) / J. Appl. Cryst. by W Kabsch (1993)
  22. Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307–326 (1996). (10.1016/S0076-6879(97)76066-X) / Methods Enzymol. by Z Otwinowski (1996)
  23. McCoy, A.J., Grosse-Kunstleve, R.W., Storoni, L.C. & Read, R.J. Likelihood-enhanced fast translation functions. Acta Crystallogr. D Biol. Crystallogr. 61, 458–464 (2005). (10.1107/S0907444905001617) / Acta Crystallogr. D Biol. Crystallogr. by AJ McCoy (2005)
  24. Armache, K.-J., Mitterweger, S., Meinhart, A. & Cramer, P. Structures of complete RNA polymerase II and its subcomplex Rpb4/7. J. Biol. Chem. 280, 7131–7134 (2005). (10.1074/jbc.M413038200) / J. Biol. Chem. by K-J Armache (2005)
  25. Brunger, A.T. et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54, 905–921 (1998). (10.1107/S0907444998003254) / Acta Crystallogr. D Biol. Crystallogr. by AT Brunger (1998)
  26. Jones, T.A., Zou, J.Y., Cowan, S.W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47, 110–119 (1991). (10.1107/S0108767390010224) / Acta Crystallogr. A by TA Jones (1991)
  27. Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr. 60, 2126–2132 (2004). (10.1107/S0907444904019158) / Acta Crystallogr. D Biol. Crystallogr. by P Emsley (2004)
Dates
Type When
Created 17 years, 9 months ago (Nov. 11, 2007, 3:04 p.m.)
Deposited 2 years, 3 months ago (May 19, 2023, 12:51 a.m.)
Indexed 3 weeks, 1 day ago (Aug. 6, 2025, 8:44 a.m.)
Issued 17 years, 9 months ago (Nov. 11, 2007)
Published 17 years, 9 months ago (Nov. 11, 2007)
Published Online 17 years, 9 months ago (Nov. 11, 2007)
Published Print 17 years, 8 months ago (Dec. 1, 2007)
Funders 0

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@article{Damsma_2007, title={Mechanism of transcriptional stalling at cisplatin-damaged DNA}, volume={14}, ISSN={1545-9985}, url={http://dx.doi.org/10.1038/nsmb1314}, DOI={10.1038/nsmb1314}, number={12}, journal={Nature Structural &amp; Molecular Biology}, publisher={Springer Science and Business Media LLC}, author={Damsma, Gerke E and Alt, Aaron and Brueckner, Florian and Carell, Thomas and Cramer, Patrick}, year={2007}, month=nov, pages={1127–1133} }