DOI: 10.1038/nsmb1032. Structure of an RNA polymerase II–RNA inhibitor complex elucidates transcription regulation by noncoding RNAs

Structure of an RNA polymerase II–RNA inhibitor complex elucidates transcription regulation by noncoding RNAs

10.1038/nsmb1032

Crossref journal-article

Springer Science and Business Media LLC

Nature Structural & Molecular Biology (297)

Bibliography

Kettenberger, H., EisenfÃ¼hr, A., Brueckner, F., Theis, M., Famulok, M., & Cramer, P. (2005). Structure of an RNA polymerase IIâRNA inhibitor complex elucidates transcription regulation by noncoding RNAs. Nature Structural & Molecular Biology, 13(1), 44â48.

Authors 6

Hubert Kettenberger (first)
Alexander Eisenführ (additional)
Florian Brueckner (additional)
Mirko Theis (additional)
Michael Famulok (additional)
Patrick Cramer (additional)

References 24 Referenced 57

Allen, T.A., Von Kaenel, S., Goodrich, J.A. & Kugel, J.F. The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock. Nat. Struct. Mol. Biol. 11, 816–821 (2004). (10.1038/nsmb813) / Nat. Struct. Mol. Biol. by TA Allen (2004)
Espinoza, C.A., Allen, T.A., Hieb, A.R., Kugel, J.F. & Goodrich, J.A. B2 RNA binds directly to RNA polymerase II to repress transcript synthesis. Nat. Struct. Mol. Biol. 11, 822–829 (2004). (10.1038/nsmb812) / Nat. Struct. Mol. Biol. by CA Espinoza (2004)
Trotochaud, A.E. & Wassarman, K.M. A highly conserved 6S RNA structure is required for regulation of transcription. Nat. Struct. Mol. Biol. 12, 313–319 (2005). (10.1038/nsmb917) / Nat. Struct. Mol. Biol. by AE Trotochaud (2005)
Wassarman, K.M. & Storz, G. 6S RNA regulates E. coli RNA polymerase activity. Cell 101, 613–623 (2000). (10.1016/S0092-8674(00)80873-9) / Cell by KM Wassarman (2000)
Barrick, J.E., Sudarsan, N., Weinberg, Z., Ruzzo, W.L. & Breaker, R.R. 6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter. RNA 11, 774–784 (2005). (10.1261/rna.7286705) / RNA by JE Barrick (2005)
Thomas, M. et al. Selective targeting and inhibition of yeast RNA polymerase II by RNA aptamers. J. Biol. Chem. 272, 27980–27986 (1997). (10.1074/jbc.272.44.27980) / J. Biol. Chem. by M Thomas (1997)
Cramer, P., Bushnell, D.A. & Kornberg, R.D. Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science 292, 1863–1876 (2001). (10.1126/science.1059493) / Science by P Cramer (2001)
Westover, K.D., Bushnell, D.A. & Kornberg, R.D. Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell 119, 481–489 (2004). (10.1016/j.cell.2004.10.016) / Cell by KD Westover (2004)
Kettenberger, H., Armache, K.-J. & Cramer, P. Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol. Cell 16, 955–965 (2004). (10.1016/j.molcel.2004.11.040) / Mol. Cell by H Kettenberger (2004)
Rasmussen, E.B. & Lis, J.T. In vitro transcriptional pausing and cap formation on three Drosophila heat shock genes. Proc. Natl. Acad. Sci. USA 90, 7923–7927 (1993). (10.1073/pnas.90.17.7923) / Proc. Natl. Acad. Sci. USA by EB Rasmussen (1993)
Lis, J. Promoter-associated pausing in promoter architecture and postinitiation transcriptional regulation. Cold Spring Harb. Symp. Quant. Biol. 63, 347–356 (1998). (10.1101/sqb.1998.63.347) / Cold Spring Harb. Symp. Quant. Biol. by J Lis (1998)
Chung, W.H. et al. RNA polymerase II/TFIIF structure and conserved organization of the initiation complex. Mol. Cell 12, 1003–1013 (2003). (10.1016/S1097-2765(03)00387-3) / Mol. Cell by WH Chung (2003)
Murakami, K.S., Masuda, S., Campbell, E.A., Muzzin, O. & Darst, S.A. Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science 296, 1285–1290 (2002). (10.1126/science.1069595) / Science by KS Murakami (2002)
Armache, K.-J., Kettenberger, H. & Cramer, P. Architecture of the initiation-competent 12-subunit RNA polymerase II. Proc. Natl. Acad. Sci. USA 100, 6964–6968 (2003). (10.1073/pnas.1030608100) / Proc. Natl. Acad. Sci. USA by K-J Armache (2003)
Chen, H.T. & Hahn, S. Mapping the location of TFIIB within the RNA polymerase II transcription preinitiation complex: a model for the structure of the PIC. Cell 119, 169–180 (2004). (10.1016/j.cell.2004.09.028) / Cell by HT Chen (2004)
Bushnell, D.A. & Kornberg, R.D. Complete RNA polymerase II at 4.1 Å resolution: implications for the initiation of transcription. Proc. Natl. Acad. Sci. USA 100, 6969–6972 (2003). (10.1073/pnas.1130601100) / Proc. Natl. Acad. Sci. USA by DA Bushnell (2003)
Bushnell, D.A., Westover, K.D., Davis, R.E. & Kornberg, R.D. Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms. Science 303, 983–988 (2004). (10.1126/science.1090838) / Science by DA Bushnell (2004)
Buratowski, S. & Zhou, H. Functional domains of transcription factor TFIIB. Proc. Natl. Acad. Sci. USA 90, 5633–5637 (1993). (10.1073/pnas.90.12.5633) / Proc. Natl. Acad. Sci. USA by S Buratowski (1993)
Pardee, T.S., Bangur, C.S. & Ponticelli, A.S. The N-terminal region of yeast TFIIB contains two adjacent functional domains involved in stable RNA polymerase II binding and transcription start site selection. J. Biol. Chem. 273, 17859–17864 (1998). (10.1074/jbc.273.28.17859) / J. Biol. Chem. by TS Pardee (1998)
Kettenberger, H. & Cramer, P. Fluorescence detection of nucleic acids and proteins in multicomponent crystals. Acta Crystallogr. D Biol. Crystallogr (in the press).
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307–326 (1996). (10.1016/S0076-6879(97)76066-X) / Methods Enzymol. by Z Otwinowski (1996)
Armache, K.-J., Mitterweger, S., Meinhart, A. & Cramer, P. Structures of complete RNA polymerase II and its subcomplex Rpb4/7. J. Biol. Chem. 280, 7131–7134 (2005). (10.1074/jbc.M413038200) / J. Biol. Chem. by K-J Armache (2005)
McCoy, A.J., Grosse-Kunstleve, R.W., Storoni, L.C. & Read, R.J. Likelihood-enhanced fast translation functions. Acta Crystallogr. D Biol. Crystallogr. 61, 458–464 (2005). (10.1107/S0907444905001617) / Acta Crystallogr. D Biol. Crystallogr. by AJ McCoy (2005)
Brunger, A.T. et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54, 905–921 (1998). (10.1107/S0907444998003254) / Acta Crystallogr. D Biol. Crystallogr. by AT Brunger (1998)

Dates

Type	When
Created	19 years, 8 months ago (Dec. 11, 2005, 4:15 p.m.)
Deposited	2 years, 3 months ago (May 19, 2023, 12:48 a.m.)
Indexed	4 months, 2 weeks ago (April 14, 2025, 6:28 p.m.)
Issued	19 years, 8 months ago (Dec. 11, 2005)
Published	19 years, 8 months ago (Dec. 11, 2005)
Published Online	19 years, 8 months ago (Dec. 11, 2005)
Published Print	19 years, 8 months ago (Jan. 1, 2006)

Funders 0

None

BibTeX

@article{Kettenberger_2005, title={Structure of an RNA polymerase II–RNA inhibitor complex elucidates transcription regulation by noncoding RNAs}, volume={13}, ISSN={1545-9985}, url={http://dx.doi.org/10.1038/nsmb1032}, DOI={10.1038/nsmb1032}, number={1}, journal={Nature Structural & Molecular Biology}, publisher={Springer Science and Business Media LLC}, author={Kettenberger, Hubert and Eisenführ, Alexander and Brueckner, Florian and Theis, Mirko and Famulok, Michael and Cramer, Patrick}, year={2005}, month=dec, pages={44–48} }

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  "URL": "http://dx.doi.org/10.1038/nsmb1032",
  "relation": {
    "has-review": [
      {
        "id-type": "doi",
        "id": "10.3410/f.1030034.351467",
        "asserted-by": "object"
      }
    ]
  },
  "ISSN": [
    "1545-9993",
    "1545-9985"
  ],
  "subject": [],
  "container-title-short": "Nat Struct Mol Biol",
  "published": {
    "date-parts": [
      [
        2005,
        12,
        11
      ]
    ]
  }
}