DOI: 10.1038/nsb947. Parallel protein-unfolding pathways revealed and mapped

Parallel protein-unfolding pathways revealed and mapped

10.1038/nsb947

Crossref journal-article

Springer Science and Business Media LLC

Nature Structural & Molecular Biology (297)

Bibliography

Wright, C. F., Lindorff-Larsen, K., Randles, L. G., & Clarke, J. (2003). Parallel protein-unfolding pathways revealed and mapped. Nature Structural & Molecular Biology, 10(8), 658â662.

Authors 4

Caroline F Wright (first)
Kresten Lindorff-Larsen (additional)
Lucy G Randles (additional)
Jane Clarke (additional)

References 32 Referenced 144

Onuchic, J.N., Luthey-Schulten, Z. & Wolynes, P.G. Theory of protein folding: the energy landscape perspective. Annu. Rev. Phys. Chem. 48, 545–600 (1997). (10.1146/annurev.physchem.48.1.545) / Annu. Rev. Phys. Chem. by JN Onuchic (1997)
Dobson, C.M., Sali, A. & Karplus, M. Protein folding: a perspective from theory and experiment. Angew. Chem. Int. Ed. 37, 868–893 (1998). (10.1002/(SICI)1521-3773(19980420)37:7<868::AID-ANIE868>3.0.CO;2-H) / Angew. Chem. Int. Ed. by CM Dobson (1998)
Baldwin, R.L. The nature of protein folding pathways: the classical versus the new view. J. Biomol. NMR 5, 103–109 (1995). (10.1007/BF00208801) / J. Biomol. NMR by RL Baldwin (1995)
Wildegger, G. & Kiefhaber, T. Three-state model for lysozyme folding: triangular folding mechanism with an energetically trapped intermediate. J. Mol. Biol. 270, 294–304 (1997). (10.1006/jmbi.1997.1030) / J. Mol. Biol. by G Wildegger (1997)
Dinner, A.R., Sali, A., Smith, L.J., Dobson, C.M. & Karplus, M. Understanding protein folding via free-energy surfaces from theory and experiment. Trends Biochem. Sci. 25, 331–339 (2000). (10.1016/S0968-0004(00)01610-8) / Trends Biochem. Sci. by AR Dinner (2000)
Zaidi, F.N., Nath, U. & Udgaonkar, J.B. Multiple intermediates and transition states during protein unfolding. Nat. Struct. Biol. 4, 1016–1023 (1997). (10.1038/nsb1297-1016) / Nat. Struct. Biol. by FN Zaidi (1997)
Baldwin, R.L. Competing unfolding pathways. Nat. Struct. Biol. 4, 965–966 (1997). (10.1038/nsb1297-965) / Nat. Struct. Biol. by RL Baldwin (1997)
Fowler, S.B. & Clarke, J. Mapping the folding pathway of an immunoglobulin domain: structural detail from phi value analysis and movement of the transition state. Structure 9, 355–366 (2001). (10.1016/S0969-2126(01)00596-2) / Structure by SB Fowler (2001)
Fersht, A.R. Optimisation of rates of protein folding: the nucleation-condensation mechanism and its implications. Biochemistry 92, 10869–10873 (1995). / Biochemistry by AR Fersht (1995)
Tanford, C. Protein denaturation. B. The transition from native to denatured state. Adv. Protein Chem. 23, 218–282 (1968). / Adv. Protein Chem. by C Tanford (1968)
Oliveberg, M., Tan, Y.-J., Silow, M. & Fersht, A.R. The changing nature of the protein folding transition state: implications for the shape of the free-energy profile for folding. J. Mol. Biol. 277, 933–943 (1998). (10.1006/jmbi.1997.1612) / J. Mol. Biol. by M Oliveberg (1998)
Hammond, G.S. A correlation of reaction rates. J. Am. Chem. Soc. 77, 334–338 (1955). (10.1021/ja01607a027) / J. Am. Chem. Soc. by GS Hammond (1955)
Matoushchek, A. & Fersht, A.R. Application of physical organic chemistry to engineered mutants of proteins: Hammond postulate behavior in the transition state of protein folding. Proc. Natl. Acad. Sci. USA 90, 7814–7818 (1993). (10.1073/pnas.90.16.7814) / Proc. Natl. Acad. Sci. USA by A Matoushchek (1993)
Sanchez, I.E. & Kiefhaber, T. Evidence for sequential barriers and obligatory intermediates in apparent two-state protein folding. J. Mol. Biol. 325, 367–376 (2002). (10.1016/S0022-2836(02)01230-5) / J. Mol. Biol. by IE Sanchez (2002)
Otzen, D.E., Kristensen, O., Proctor, M. & Oliveberg, M. Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots. Biochemistry 38, 6499–6511 (1999). (10.1021/bi982819j) / Biochemistry by DE Otzen (1999)
Matthews, J.M. & Fersht, A.R. Exploring the energy surface of protein folding by structure-reactivity relationships and engineering proteins: observation of Hammond behavior for the gross structure of the transition state and anti-Hammond behavior for structural elements for unfolding/folding of barnase. Biochemistry 34, 6805–6814 (1995). (10.1021/bi00020a027) / Biochemistry by JM Matthews (1995)
Dalby, P.A., Oliveberg, M. & Fersht, A.R. Movement of the intermediate and rate determining state of barnase on the energy landscape with changing temperature. Biochemistry 37, 4674–4679 (1998). (10.1021/bi972798d) / Biochemistry by PA Dalby (1998)
Daggett, V., Li, A. & Fersht, A.R. Combined molecular dynamics and Φ-value analysis of structure-reactivity relationships in the transition state and unfolding pathway of barnase: structural basis of Hammond and anti-Hammond effects. J. Am. Chem. Soc. 120, 12740–12754 (1998). (10.1021/ja981558y) / J. Am. Chem. Soc. by V Daggett (1998)
Otzen, D.E. & Oliveberg, M. Conformational plasticity in folding of the split β–α–β protein S6: evidence for burst-phase disruption of the native state. J. Mol. Biol. 317, 613–627 (2002). (10.1006/jmbi.2002.5423) / J. Mol. Biol. by DE Otzen (2002)
Fersht, A.R., Itzhaki, L.S., ElMasry, N.F., Matthews, J.M. & Otzen, D.E. Single versus parallel pathways of protein folding and fractional formation of structure in the transition state. Proc. Natl. Acad. Sci. USA 91, 10426–10429 (1994). (10.1073/pnas.91.22.10426) / Proc. Natl. Acad. Sci. USA by AR Fersht (1994)
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Myers, J. & Oas, T.G. Mechanisms of fast protein folding. Annu. Rev. Biochem. 71, 783–815 (2002). (10.1146/annurev.biochem.71.110601.135346) / Annu. Rev. Biochem. by J Myers (2002)
Sanchez, I.E. & Kiefhaber, T. Hammond behavior versus ground state effects in protein folding: evidence for narrow free energy barriers and residual structure in unfolded states. J. Mol. Biol. 327, 867–884 (2003). (10.1016/S0022-2836(03)00171-2) / J. Mol. Biol. by IE Sanchez (2003)
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Dates

Type	When
Created	22 years, 2 months ago (June 27, 2003, 10:16 a.m.)
Deposited	2 years, 3 months ago (May 19, 2023, 12:22 a.m.)
Indexed	2 months, 4 weeks ago (June 5, 2025, 9:41 a.m.)
Issued	22 years, 2 months ago (June 29, 2003)
Published	22 years, 2 months ago (June 29, 2003)
Published Online	22 years, 2 months ago (June 29, 2003)
Published Print	22 years, 1 month ago (Aug. 1, 2003)

Funders 0

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BibTeX

@article{Wright_2003, title={Parallel protein-unfolding pathways revealed and mapped}, volume={10}, ISSN={1545-9985}, url={http://dx.doi.org/10.1038/nsb947}, DOI={10.1038/nsb947}, number={8}, journal={Nature Structural & Molecular Biology}, publisher={Springer Science and Business Media LLC}, author={Wright, Caroline F and Lindorff-Larsen, Kresten and Randles, Lucy G and Clarke, Jane}, year={2003}, month=jun, pages={658–662} }

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