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Takahasi, K., Suzuki, N. N., Horiuchi, M., Mori, M., Suhara, W., Okabe, Y., Fukuhara, Y., Terasawa, H., Akira, S., Fujita, T., & Inagaki, F. (2003). X-ray crystal structure of IRF-3 and its functional implications. Nature Structural & Molecular Biology, 10(11), 922–927.

Authors 11
  1. Kiyohiro Takahasi (first)
  2. Nobuo N Suzuki (additional)
  3. Masataka Horiuchi (additional)
  4. Mitsuaki Mori (additional)
  5. Wakako Suhara (additional)
  6. Yasutaka Okabe (additional)
  7. Yukiko Fukuhara (additional)
  8. Hiroaki Terasawa (additional)
  9. Shizuo Akira (additional)
  10. Takashi Fujita (additional)
  11. Fuyuhiko Inagaki (additional)
References 36 Referenced 141
  1. Kawai, T. et al. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167, 5887–5894 (2001). (10.4049/jimmunol.167.10.5887) / J. Immunol. by T Kawai (2001)
  2. Doyle, S. et al. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17, 251–263 (2002). (10.1016/S1074-7613(02)00390-4) / Immunity by S Doyle (2002)
  3. Kaisho, T. & Akira, S. Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice. Trends Immunol. 22, 78–83 (2001). (10.1016/S1471-4906(00)01811-1) / Trends Immunol. by T Kaisho (2001)
  4. Mamane, Y. et al. Interferon regulatory factors: the next generation. Gene 237, 1–14 (1999). (10.1016/S0378-1119(99)00262-0) / Gene by Y Mamane (1999)
  5. Taniguchi, T., Ogasawara, K., Takaoka, A. & Tanaka, N. IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19, 623–655 (2001). (10.1146/annurev.immunol.19.1.623) / Annu. Rev. Immunol. by T Taniguchi (2001)
  6. Alexopoulou, L., Holt, A.C., Medzhitov, R. & Flavell, R.A. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413, 732–738 (2001). (10.1038/35099560) / Nature by L Alexopoulou (2001)
  7. Yoneyama, M., Suhara, W. & Fujita, T. Control of IRF-3 activation by phosphorylation. J. Interferon Cytokine Res. 22, 73–76 (2002). (10.1089/107999002753452674) / J. Interferon Cytokine Res. by M Yoneyama (2002)
  8. Sato, M. et al. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction. Immunity 13, 539–548 (2000). (10.1016/S1074-7613(00)00053-4) / Immunity by M Sato (2000)
  9. Yoneyama, M. et al. Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J. 17, 1087–1095 (1998). (10.1093/emboj/17.4.1087) / EMBO J. by M Yoneyama (1998)
  10. Iwamura, T. et al. Induction of IRF-3/-7 kinase and NF-κB in response to double-stranded RNA and virus infection: common and unique pathways. Genes Cells 6, 375–388 (2001). (10.1046/j.1365-2443.2001.00426.x) / Genes Cells by T Iwamura (2001)
  11. Marie, I., Durbin, J.E. & Levy, D.E. Differential viral induction of distinct interferon-α genes by positive feedback through interferon regulatory factor-7. EMBO J. 17, 6660–6669 (1998). (10.1093/emboj/17.22.6660) / EMBO J. by I Marie (1998)
  12. Lin, R., Mamane, Y. & Hiscott, J. Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains. Mol. Cell. Biol. 19, 2465–2474 (1999). (10.1128/MCB.19.4.2465) / Mol. Cell. Biol. by R Lin (1999)
  13. Holm, L. & Sander, C. Protein structure comparison by alignment of distance matrices. J. Mol. Biol. 233, 123–138 (1993). (10.1006/jmbi.1993.1489) / J. Mol. Biol. by L Holm (1993)
  14. Wu, J. et al. Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-β signaling. Mol. Cell 8, 1277–1289 (2001). (10.1016/S1097-2765(01)00421-X) / Mol. Cell by J Wu (2001)
  15. Shi, Y., Hata, A., Lo, R.S. & Massague, J. & Pavletich, N.P. A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature 388, 87–93 (1997). (10.1038/40431) / Nature by Y Shi (1997)
  16. Qin, B., Lam, S.S. & Lin, K. Crystal structure of a transcriptionally active Smad4 fragment. Structure Fold. Des. 7, 1493–1503 (1999). (10.1016/S0969-2126(00)88340-9) / Structure Fold. Des. by B Qin (1999)
  17. Suhara, W. et al. Analyses of virus-induced homomeric and heteromeric protein associations between IRF-3 and coactivator CBP/p300. J. Biochem. 128, 301–307 (2000). (10.1093/oxfordjournals.jbchem.a022753) / J. Biochem. by W Suhara (2000)
  18. Onishi, M. et al. Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation. Mol. Cell. Biol. 18, 3871–3879 (1998). (10.1128/MCB.18.7.3871) / Mol. Cell. Biol. by M Onishi (1998)
  19. Yang, H. et al. Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein-protein interactions. Eur. J. Biochem. 269, 6142–6151 (2002). (10.1046/j.1432-1033.2002.03330.x) / Eur. J. Biochem. by H Yang (2002)
  20. Sharma, S. et al. Triggering the interferon antiviral response through an IKK-related pathway. Science 300, 1148–1151 (2003). (10.1126/science.1081315) / Science by S Sharma (2003)
  21. Fitzgerald, K.A. et al. IKKε and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4, 491–496 (2003). (10.1038/ni921) / Nat. Immunol. by KA Fitzgerald (2003)
  22. Lin, C.H. et al. A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies. Mol. Cell 8, 581–590 (2001). (10.1016/S1097-2765(01)00333-1) / Mol. Cell by CH Lin (2001)
  23. Demarest, S.J. et al. Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature 415, 549–553 (2002). (10.1038/415549a) / Nature by SJ Demarest (2002)
  24. Qin, B. et al. Crystal structure of IRF-3 transactivation domain: autoinhibition and virus-induced phospho-activation. Nat. Struct. Biol. advance online publication, 12 October 2003 (doi: 10.1038/nsb1002). (10.1038/nsb1002)
  25. Eroshkin, A. & Mushegian, A. Conserved transactivation domain shared by interferon regulatory factors and Smad morphogens. J. Mol. Med. 77, 403–405 (1999). (10.1007/s001090050369) / J. Mol. Med. by A Eroshkin (1999)
  26. Durocher, D. et al. The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms. Mol. Cell 6, 1169–1182 (2000) (10.1016/S1097-2765(00)00114-3) / Mol. Cell by D Durocher (2000)
  27. Yasukawa, T. et al. Increase of solubility of foreign proteins in Escherichia coli by coproduction of the bacterial thioredoxin. J. Biol. Chem. 270, 25328–25331 (1995). (10.1074/jbc.270.43.25328) / J. Biol. Chem. by T Yasukawa (1995)
  28. Leslie, A.G.W. Mosflm User Guide, Mosflm Version 6.0 (MRC Laboratory of Molecular Biology, Cambridge, UK, 1999). / Mosflm User Guide, Mosflm Version 6.0 by AGW Leslie (1999)
  29. Collaborative Computing Project Number 4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760–763 (1994). (10.1107/S0907444994003112)
  30. Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307–326 (1997). (10.1016/S0076-6879(97)76066-X) / Methods Enzymol. by Z Otwinowski (1997)
  31. Brnnger, A.T. et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D 54, 905–921 (1991). (10.1107/S0907444998003254) / Acta Crystallogr. D by AT Brnnger (1991)
  32. Roussel, A. & Cambillau, C. TURBO-FRODO Manual (AFMB-CNRS, Marseille, France, 1996). / TURBO-FRODO Manual by A Roussel (1996)
  33. Kraulis, P.J. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24, 946–950 (1991). (10.1107/S0021889891004399) / J. Appl. Crystallogr. by PJ Kraulis (1991)
  34. Merritt, E.A. & Bacon, J.A. Raster3D: photorealistic molecular graphics. Methods Enzymol. 277, 505–524 (1997). (10.1016/S0076-6879(97)77028-9) / Methods Enzymol. by EA Merritt (1997)
  35. Jones, T.A., Zhou, J.Y., Cowan, S.W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47, 110–119 (1991). (10.1107/S0108767390010224) / Acta Crystallogr. A by TA Jones (1991)
  36. Nicholls, A., Sharp, K.A. & Honig, B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11, 281–296 (1991). (10.1002/prot.340110407) / Proteins by A Nicholls (1991)
Dates
Type When
Created 21 years, 10 months ago (Oct. 12, 2003, 2:36 p.m.)
Deposited 2 years, 3 months ago (May 19, 2023, 12:20 a.m.)
Indexed 1 month, 1 week ago (July 24, 2025, 7:13 a.m.)
Issued 21 years, 10 months ago (Oct. 12, 2003)
Published 21 years, 10 months ago (Oct. 12, 2003)
Published Online 21 years, 10 months ago (Oct. 12, 2003)
Published Print 21 years, 10 months ago (Nov. 1, 2003)
Funders 0

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@article{Takahasi_2003, title={X-ray crystal structure of IRF-3 and its functional implications}, volume={10}, ISSN={1545-9985}, url={http://dx.doi.org/10.1038/nsb1001}, DOI={10.1038/nsb1001}, number={11}, journal={Nature Structural & Molecular Biology}, publisher={Springer Science and Business Media LLC}, author={Takahasi, Kiyohiro and Suzuki, Nobuo N and Horiuchi, Masataka and Mori, Mitsuaki and Suhara, Wakako and Okabe, Yasutaka and Fukuhara, Yukiko and Terasawa, Hiroaki and Akira, Shizuo and Fujita, Takashi and Inagaki, Fuyuhiko}, year={2003}, month=oct, pages={922–927} }