DOI: 10.1038/nrc1977. Topoisomerase I inhibitors: camptothecins and beyond

Topoisomerase I inhibitors: camptothecins and beyond

10.1038/nrc1977

Crossref journal-article

Springer Science and Business Media LLC

Nature Reviews Cancer (297)

Bibliography

Pommier, Y. (2006). Topoisomerase I inhibitors: camptothecins and beyond. Nature Reviews Cancer, 6(10), 789â802.

Authors 1

Yves Pommier (first)

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Dates

Type	When
Created	18 years, 11 months ago (Sept. 22, 2006, 2:18 a.m.)
Deposited	2 years, 3 months ago (May 23, 2023, 9:18 a.m.)
Indexed	6 days, 13 hours ago (Aug. 29, 2025, 6:09 a.m.)
Issued	18 years, 11 months ago (Oct. 1, 2006)
Published	18 years, 11 months ago (Oct. 1, 2006)
Published Print	18 years, 11 months ago (Oct. 1, 2006)

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BibTeX

@article{Pommier_2006, title={Topoisomerase I inhibitors: camptothecins and beyond}, volume={6}, ISSN={1474-1768}, url={http://dx.doi.org/10.1038/nrc1977}, DOI={10.1038/nrc1977}, number={10}, journal={Nature Reviews Cancer}, publisher={Springer Science and Business Media LLC}, author={Pommier, Yves}, year={2006}, month=oct, pages={789–802} }

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      "doi-asserted-by": "crossref",
      "first-page": "671",
      "DOI": "10.1038/nature03395",
      "volume": "434",
      "author": "DA Koster",
      "year": "2005",
      "unstructured": "Koster, D. A., Croquette, V., Dekker, C., Shuman, S. & Dekker, N. H. Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB. Nature. 434, 671\u2013674 (2005). Provides direct evidence of the controlled rotation of DNA in TOP1ccs using single-molecule analyses.",
      "journal-title": "Nature."
    },
    {
      "key": "BFnrc1977_CR13",
      "doi-asserted-by": "crossref",
      "first-page": "729",
      "DOI": "10.1016/S1097-2765(00)80072-6",
      "volume": "1",
      "author": "C-J Xu",
      "year": "1998",
      "unstructured": "Xu, C.-J., Grainge, I., Lee, J., Harshey, R. M. & Jayaram, M. Unveiling two distinct ribonuclease activities and a topoisomerase activity in a site-specific DNA recombinase. Mol. Cell. 1, 729\u2013739 (1998).",
      "journal-title": "Mol. Cell."
    },
    {
      "key": "BFnrc1977_CR14",
      "doi-asserted-by": "crossref",
      "first-page": "1919",
      "DOI": "10.1093/nar/27.8.1919",
      "volume": "27",
      "author": "P Pourquier",
      "year": "1999",
      "unstructured": "Pourquier, P., Jensen, A. D., Gong, S. S., Pommier, Y. & Rogler, C. E. Human DNA topoisomerase I-mediated cleavage and recombination of duck hepatitis B virus DNA in vitro. Nucleic Acids Res. 27, 1919\u20131923 (1999).",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "BFnrc1977_CR15",
      "doi-asserted-by": "crossref",
      "first-page": "8059",
      "DOI": "10.1128/MCB.20.21.8059-8068.2000",
      "volume": "20",
      "author": "C Cheng",
      "year": "2000",
      "unstructured": "Cheng, C. & Shuman, S. Recombinogenic flap ligation pathway for intrinsic repair of topoisomerase IB-induced double-strand breaks. Mol. Cell. Biol. 20, 8059\u20138068 (2000).",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "BFnrc1977_CR16",
      "doi-asserted-by": "crossref",
      "first-page": "189",
      "DOI": "10.1016/S0065-230X(01)80016-6",
      "volume": "80",
      "author": "P Pourquier",
      "year": "2001",
      "unstructured": "Pourquier, P. & Pommier, Y. Topoisomerase I-mediated DNA damage. Adv. Cancer Res. 80, 189\u2013216 (2001). Reviews the broad range of DNA damages that trap TOP1 and describes the molecular mechanisms involved in the trapping of TOP1.",
      "journal-title": "Adv. Cancer Res."
    },
    {
      "key": "BFnrc1977_CR17",
      "doi-asserted-by": "crossref",
      "first-page": "173",
      "DOI": "10.1016/j.mrfmmm.2003.08.016",
      "volume": "532",
      "author": "Y Pommier",
      "year": "2003",
      "unstructured": "Pommier, Y. et al. Repair of and checkpoint response to topoisomerase I-mediated DNA damage. Mutat. Res. 532, 173\u2013203 (2003). A detailed review with particular emphasis on the checkpoint and repair pathways that are involved in the cellular responses to TOP1 covalent complexes.",
      "journal-title": "Mutat. Res."
    },
    {
      "key": "BFnrc1977_CR18",
      "doi-asserted-by": "crossref",
      "first-page": "50499",
      "DOI": "10.1074/jbc.M410277200",
      "volume": "279",
      "author": "O Sordet",
      "year": "2004",
      "unstructured": "Sordet, O. et al. Apoptotic topoisomerase I-DNA complexes induced by staurosporine-mediated oxygen radicals. J. Biol. Chem. 279, 50499\u201350504 (2004).",
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    {
      "key": "BFnrc1977_CR19",
      "doi-asserted-by": "crossref",
      "first-page": "1095",
      "DOI": "10.4161/cc.3.9.1086",
      "volume": "3",
      "author": "O Sordet",
      "year": "2004",
      "unstructured": "Sordet, O., Khan, Q. A. & Pommier, Y. Apoptotic topoisomerase I-DNA complexes induced by oxygen radicals and mitochondrial dysfunction. Cell Cycle 3, 1095\u20131097 (2004). Reviews the generality of apoptotic TOP1 covalent complexes.",
      "journal-title": "Cell Cycle"
    },
    {
      "key": "BFnrc1977_CR20",
      "doi-asserted-by": "crossref",
      "first-page": "33968",
      "DOI": "10.1074/jbc.M404620200",
      "volume": "279",
      "author": "O Sordet",
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      "unstructured": "Sordet, O. et al. Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis. J. Biol. Chem. 279, 33968\u201333975 (2004).",
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    },
    {
      "key": "BFnrc1977_CR21",
      "doi-asserted-by": "crossref",
      "first-page": "314",
      "DOI": "10.1006/excr.1994.1093",
      "volume": "211",
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    {
      "key": "BFnrc1977_CR22",
      "first-page": "753",
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      "unstructured": "Wall, M. E. & Wani, M. C. Camptothecin and taxol: discovery to clinic \u2014 thirteenth Bruce F. Cain Memorial Award lecture. Cancer Res. 55, 753\u2013760 (1995).",
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    {
      "key": "BFnrc1977_CR23",
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      "first-page": "14873",
      "DOI": "10.1016/S0021-9258(17)38654-4",
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    {
      "key": "BFnrc1977_CR24",
      "first-page": "755",
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      "unstructured": "Eng, W. K., Faucette, L., Johnson, R. K. & Sternglanz, R. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. Mol. Pharmacol. 34, 755\u2013760 (1988). Shows that TOP1 is the only cellular target of camptothecin as TOP1-deficient yeast cells are immune to camptothecin.",
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    {
      "key": "BFnrc1977_CR25",
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      "DOI": "10.1073/pnas.85.20.7501",
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      "unstructured": "Nitiss, J. & Wang, J. C. DNA topoisomerase-targeting antitumor drugs can be studied in yeast. Proc. Natl Acad. Sci. USA 85, 7501\u20137505 (1988). Shows that TOP1 is the sole target of camptothecin and that yeast can be used for pharmacological studies and drug discovery.",
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    {
      "key": "BFnrc1977_CR26",
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      "DOI": "10.1124/mol.54.1.50",
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      "unstructured": "Jaxel, C., Kohn, K. W., Wani, M. C., Wall, M. E. & Pommier, Y. Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity. Cancer Res. 49, 1465\u20131469 (1989).",
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    {
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