DOI: 10.1038/nprot.2006.5. The comet assay: a method to measure DNA damage in individual cells

The comet assay: a method to measure DNA damage in individual cells

10.1038/nprot.2006.5

Crossref journal-article

Springer Science and Business Media LLC

Nature Protocols (297)

Bibliography

Olive, P. L., & BanÃ¡th, J. P. (2006). The comet assay: a method to measure DNA damage in individual cells. Nature Protocols, 1(1), 23â29.

Authors 2

Peggy L Olive (first)
Judit P Banáth (additional)

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Singh, N.P., McCoy, M.T., Tice, R.R. & Schneider, E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175, 184–191 (1988). (10.1016/0014-4827(88)90265-0) / Exp. Cell Res. by NP Singh (1988)
Rydberg, B. The rate of strand separation in alkali of DNA of irradiated mammalian cells. Radiat. Res. 61, 274–287 (1975). (10.2307/3574045) / Radiat. Res. by B Rydberg (1975)
Kohn, K.W. & Grimek-Ewig, R.A. Alkaline elution analysis, a new approach to the study of DNA single-strand interruptions in cells. Cancer Res. 33, 1849–1853 (1973). / Cancer Res. by KW Kohn (1973)
Olive, P.L. Cell proliferation as a requirement for development of the contact effect in Chinese hamster V79 spheroids. Radiat. Res. 117, 79–92 (1989). (10.2307/3577279) / Radiat. Res. by PL Olive (1989)
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Fairbairn, D.W., Olive, P.L. & O'Neill, K.L. The comet assay: a comprehensive review. Mutat. Res. 339, 37–59 (1995). (10.1016/0165-1110(94)00013-3) / Mutat. Res. by DW Fairbairn (1995)
Salagovic, J., Gilles, J., Verschaeve, L. & Kalina, I. The comet assay for the detection of genotoxic damage in the earthworms: a promising tool for assessing the biological hazards of polluted sites. Folia Biol. (Praha.) 42, 17–21 (1996). / Folia Biol. (Praha.) by J Salagovic (1996)
Moller, P. Genotoxicity of environmental agents assessed by the alkaline comet assay. Basic Clin. Pharmacol. Toxicol. 96 (Suppl. 1), 1–42 (2005). / Basic Clin. Pharmacol. Toxicol. by P Moller (2005)
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Bauch, T., Bocker, W., Mallek, U., Muller, W.U. & Streffer, C. Optimization and standardization of the “comet assay” for analyzing the repair of DNA damage in cells. Strahlenther. Onkol. 175, 333–340 (1999). (10.1007/s000660050020) / Strahlenther. Onkol. by T Bauch (1999)
Banath, J.P., Kim, A. & Olive, P.L. Overnight lysis improves the efficiency of detection of DNA damage in the alkaline comet assay. Radiat. Res. 155, 564–571 (2001). (10.1667/0033-7587(2001)155[0564:OLITEO]2.0.CO;2) / Radiat. Res. by JP Banath (2001)
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Merk, O. & Speit, G. Detection of crosslinks with the comet assay in relationship to genotoxicity and cytotoxicity. Environ. Mol. Mutagen. 33, 167–172 (1999). (10.1002/(SICI)1098-2280(1999)33:2<167::AID-EM9>3.0.CO;2-D) / Environ. Mol. Mutagen. by O Merk (1999)
Olive, P.L., Frazer, G. &p Banáth, J.P. Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay. Radiat. Res. 136, 130–136 (1993). (10.2307/3578650) / Radiat. Res. by PL Olive (1993)
Ostling, O. & Johanson, K.J. Bleomycin, in contrast to gamma irradiation, induces extreme variation of DNA strand breakage from cell to cell. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 52, 683–691 (1987). (10.1080/09553008714552201) / Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. by O Ostling (1987)
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Dates

Type	When
Created	19 years ago (July 27, 2006, 4:11 p.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 8:04 p.m.)
Indexed	2 days, 1 hour ago (Aug. 20, 2025, 9:13 a.m.)
Issued	19 years, 2 months ago (June 1, 2006)
Published	19 years, 2 months ago (June 1, 2006)
Published Online	19 years, 1 month ago (June 27, 2006)
Published Print	19 years, 2 months ago (June 1, 2006)

Funders 0

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BibTeX

@article{Olive_2006, title={The comet assay: a method to measure DNA damage in individual cells}, volume={1}, ISSN={1750-2799}, url={http://dx.doi.org/10.1038/nprot.2006.5}, DOI={10.1038/nprot.2006.5}, number={1}, journal={Nature Protocols}, publisher={Springer Science and Business Media LLC}, author={Olive, Peggy L and Banáth, Judit P}, year={2006}, month=jun, pages={23–29} }

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