Stereotaxic gene delivery in the rodent brain
10.1038/nprot.2006.450
Crossref journal-article
Springer Science and Business Media LLC
Nature Protocols (297)
Bibliography

Cetin, A., Komai, S., Eliava, M., Seeburg, P. H., & Osten, P. (2006). Stereotaxic gene delivery in the rodent brain. Nature Protocols, 1(6), 3166–3173.

Authors 5
  1. Ali Cetin (first)
  2. Shoji Komai (additional)
  3. Marina Eliava (additional)
  4. Peter H Seeburg (additional)
  5. Pavel Osten (additional)
References 33 Referenced 262
  1. Deglon, N. & Aebischer, P. Lentiviruses as vectors for CNS diseases. Curr. Top. Microbiol. Immunol. 261, 191–209 (2002). / Curr. Top. Microbiol. Immunol. by N Deglon (2002)
  2. Tenenbaum, L. et al. Recombinant AAV-mediated gene delivery to the central nervous system. J. Gene Med. 6 Suppl 1, S212–S222 (2004). (10.1002/jgm.506) / J. Gene Med. by L Tenenbaum (2004)
  3. Osten, P., Dittgen, T. & Licznerski, P. in The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology (eds. Moss, S. & Kittler, J.) 249–259 (CRC, Boca Raton, 2006) / The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology by P Osten (2006)
  4. Szczesny, G., Veihelmann, A., Massberg, S., Nolte, D. & Messmer, K. Long-term anaesthesia using inhalatory isoflurane in different strains of mice-the haemodynamic effects. Lab. Anim. 38, 64–69 (2004). (10.1258/00236770460734416) / Lab. Anim. by G Szczesny (2004)
  5. Jevtovic-Todorovic, V. et al. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J. Neurosci. 23, 876–882 (2003). (10.1523/JNEUROSCI.23-03-00876.2003) / J. Neurosci. by V Jevtovic-Todorovic (2003)
  6. Phifer, C.B. & Terry, L.M. Use of hypothermia for general anesthesia in preweanling rodents. Physiol. Behav. 38, 887–890 (1986). (10.1016/0031-9384(86)90058-2) / Physiol. Behav. by CB Phifer (1986)
  7. Danneman, P.J. & Mandrell, T.D. Evaluation of five agents/methods for anesthesia of neonatal rats. Lab. Anim. Sci. 47, 386–395 (1997). / Lab. Anim. Sci. by PJ Danneman (1997)
  8. Büchen-Osmond, C. The Universal Virus Database of the International Committee on Taxonomy of Viruses < http://www.ncbi.nlm.nih.gov/ICTVdb/index.htm > (2001).
  9. Van Harreveld, A. in The Structure and Function of Nervous Tissue (ed. Bourne, G.H.) 447–511 (Academic Press, 1972). (10.1016/B978-0-12-119284-6.50015-4) / The Structure and Function of Nervous Tissue by A Van Harreveld (1972)
  10. Thorne, R.G. & Nicholson, C. In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proc. Natl. Acad. Sci. USA 103, 5567–5572 (2006). (10.1073/pnas.0509425103) / Proc. Natl. Acad. Sci. USA by RG Thorne (2006)
  11. Lieberman, D.M., Laske, D.W., Morrison, P.F., Bankiewicz, K.S. & Oldfield, E.H. Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion. J. Neurosurg. 82, 1021–1029 (1995). (10.3171/jns.1995.82.6.1021) / J. Neurosurg. by DM Lieberman (1995)
  12. Cunningham, J. et al. Distribution of AAV-TK following intracranial convection-enhanced delivery into rats. Cell Transplant. 9, 585–594 (2000). (10.1177/096368970000900504) / Cell Transplant. by J Cunningham (2000)
  13. Nguyen, J.B., Sanchez-Pernaute, R., Cunningham, J. & Bankiewicz, K.S. Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain. Neuroreport 12, 1961–1964 (2001). (10.1097/00001756-200107030-00037) / Neuroreport by JB Nguyen (2001)
  14. Mastakov, M.Y., Baer, K., Xu, R., Fitzsimons, H. & During, M.J. Combined injection of rAAV with mannitol enhances gene expression in the rat brain. Mol. Ther. 3, 225–232 (2001). (10.1006/mthe.2001.0246) / Mol. Ther. by MY Mastakov (2001)
  15. Xu, R. et al. Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes. Gene Ther. 8, 1323–1332 (2001). (10.1038/sj.gt.3301529) / Gene Ther. by R Xu (2001)
  16. Kugler, S., Lingor, P., Scholl, U., Zolotukhin, S. & Bahr, M. Differential transgene expression in brain cells in vivo and in vitro from AAV-2 vectors with small transcriptional control units. Virology 311, 89–95 (2003). (10.1016/S0042-6822(03)00162-4) / Virology by S Kugler (2003)
  17. Klugmann, M. et al. AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats. Mol. Cell. Neurosci. 28, 347–360 (2005). (10.1016/j.mcn.2004.10.002) / Mol. Cell. Neurosci. by M Klugmann (2005)
  18. Callaway, E.M. A molecular and genetic arsenal for systems neuroscience. Trends Neurosci. 28, 196–201 (2005). (10.1016/j.tins.2005.01.007) / Trends Neurosci. by EM Callaway (2005)
  19. Burger, C. et al. Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Mol. Ther. 10, 302–317 (2004). (10.1016/j.ymthe.2004.05.024) / Mol. Ther. by C Burger (2004)
  20. Davidson, B.L. et al. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proc. Natl. Acad. Sci. USA 97, 3428–3432 (2000). (10.1073/pnas.97.7.3428) / Proc. Natl. Acad. Sci. USA by BL Davidson (2000)
  21. Burns, J.C., Friedmann, T., Driever, W., Burrascano, M. & Yee, J.K. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. USA 90, 8033–8037 (1993). (10.1073/pnas.90.17.8033) / Proc. Natl. Acad. Sci. USA by JC Burns (1993)
  22. Wiznerowicz, M. & Trono, D. Harnessing HIV for therapy, basic research and biotechnology. Trends Biotechnol. 23, 42–47 (2005). (10.1016/j.tibtech.2004.11.001) / Trends Biotechnol. by M Wiznerowicz (2005)
  23. Mazarakis, N.D. et al. Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery. Hum. Mol. Genet. 10, 2109–2121 (2001). (10.1093/hmg/10.19.2109) / Hum. Mol. Genet. by ND Mazarakis (2001)
  24. Muller, O.J. et al. Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nat. Biotechnol. 21, 1040–1046 (2003). (10.1038/nbt856) / Nat. Biotechnol. by OJ Muller (2003)
  25. Yang, L., Bailey, L., Baltimore, D. & Wang, P. Targeting lentiviral vectors to specific cell types in vivo. Proc. Natl. Acad. Sci. USA 103, 11479–11484 (2006). (10.1073/pnas.0604993103) / Proc. Natl. Acad. Sci. USA by L Yang (2006)
  26. Dittgen, T. et al. Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo. Proc. Natl. Acad. Sci. USA 101, 18206–18211 (2004). (10.1073/pnas.0407976101) / Proc. Natl. Acad. Sci. USA by T Dittgen (2004)
  27. Grinevich, V., Brecht, M. & Osten, P. Monosynaptic pathway from rat vibrissa motor cortex to facial motor neurons revealed by lentivirus-based axonal tracing. J. Neurosci. 25, 8250–8258 (2005). (10.1523/JNEUROSCI.2235-05.2005) / J. Neurosci. by V Grinevich (2005)
  28. Margrie, T.W. et al. Targeted whole-cell recordings in the mammalian brain in vivo. Neuron 39, 911–918 (2003). (10.1016/j.neuron.2003.08.012) / Neuron by TW Margrie (2003)
  29. Komai, S., Denk, W., Osten, P., Brecht, M. & Margrie, T.W. Two-photon targeted patching (TPTP) in vivo. Nat. Protoc. 1, 648–653 (2006). (10.1038/nprot.2006.100) / Nat. Protoc. by S Komai (2006)
  30. Komai, S. et al. Postsynaptic excitability is necessary for strengthening of cortical sensory responses during experience-dependent development. Nat. Neurosci. 9, 1125–1133 (2006). (10.1038/nn1752) / Nat. Neurosci. by S Komai (2006)
  31. Maskos, U. et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature 436, 103–107 (2005). (10.1038/nature03694) / Nature by U Maskos (2005)
  32. Rumpel, S., LeDoux, J., Zador, A. & Malinow, R. Postsynaptic receptor trafficking underlying a form of associative learning. Science 308, 83–88 (2005). (10.1126/science.1103944) / Science by S Rumpel (2005)
  33. Davis, J.A. Mouse and rat anesthesia and analgesia in Current Protocols in Neuroscience: Appendix 4 Animal Techniques (eds. Crawley, J.N., Gerfen, C.R., Rogawski, M.A., Sibley, D.R., Skolnick, P. & Wray, S.) A.4B.1–A.4B.17 (John Wiley & Sons, Inc., NY, 2001). / Current Protocols in Neuroscience: Appendix 4 Animal Techniques by JA Davis (2001)
Dates
Type When
Created 18 years, 7 months ago (Feb. 2, 2007, 10:56 p.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 8:03 p.m.)
Indexed 1 week, 5 days ago (Aug. 23, 2025, 9:16 p.m.)
Issued 18 years, 9 months ago (Dec. 1, 2006)
Published 18 years, 9 months ago (Dec. 1, 2006)
Published Online 18 years, 7 months ago (Jan. 31, 2007)
Published Print 18 years, 9 months ago (Dec. 1, 2006)
Funders 0

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@article{Cetin_2006, title={Stereotaxic gene delivery in the rodent brain}, volume={1}, ISSN={1750-2799}, url={http://dx.doi.org/10.1038/nprot.2006.450}, DOI={10.1038/nprot.2006.450}, number={6}, journal={Nature Protocols}, publisher={Springer Science and Business Media LLC}, author={Cetin, Ali and Komai, Shoji and Eliava, Marina and Seeburg, Peter H and Osten, Pavel}, year={2006}, month=dec, pages={3166–3173} }