LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1
10.1038/nn779
Crossref journal-article
Springer Science and Business Media LLC
Nature Neuroscience (297)
Bibliography

Grosshans, D. R., Clayton, D. A., Coultrap, S. J., & Browning, M. D. (2001). LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nature Neuroscience, 5(1), 27–33.

Authors 4
  1. D. R. Grosshans (first)
  2. D. A. Clayton (additional)
  3. S. J. Coultrap (additional)
  4. M. D. Browning (additional)
References 47 Referenced 314
  1. Shi, S. H. et al. Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science 284, 1811–1816 (1999). (10.1126/science.284.5421.1811) / Science by SH Shi (1999)
  2. Hayashi, Y. et al. Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science 287, 2262–2267 (2000). (10.1126/science.287.5461.2262) / Science by Y Hayashi (2000)
  3. Petralia, R. S. et al. Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses. Nat. Neurosci. 2, 31–36 (1999). (10.1038/4532) / Nat. Neurosci. by RS Petralia (1999)
  4. Nusser, Z. et al. Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus. Neuron 21, 545–559 (1998). (10.1016/S0896-6273(00)80565-6) / Neuron by Z Nusser (1998)
  5. Racca, C., Stephenson, F. A., Streit, P., Roberts, J. D. & Somogyi, P. NMDA receptor content of synapses in stratum radiatum of the hippocampal CA1 area. J. Neurosci. 20, 2512–2522 (2000). (10.1523/JNEUROSCI.20-07-02512.2000) / J. Neurosci. by C Racca (2000)
  6. Lan, J. et al. Protein kinase C modulates NMDA receptor trafficking and gating. Nat. Neurosci. 4, 382–390 (2001). (10.1038/86028) / Nat. Neurosci. by J Lan (2001)
  7. Lu, W. Y. et al. G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors. Nat. Neurosci. 2, 331–338 (1999). (10.1038/7243) / Nat. Neurosci. by WY Lu (1999)
  8. Huang, Y. et al. CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron 29, 485–496 (2001). (10.1016/S0896-6273(01)00220-3) / Neuron by Y Huang (2001)
  9. O'Dell, T. J., Kandel, E. R. & Grant, S. G. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature 353, 558–560 (1991). (10.1038/353558a0) / Nature by TJ O'Dell (1991)
  10. Hall, R. A. & Soderling, T. R. Quantitation of AMPA receptor surface expression in cultured hippocampal neurons. Neuroscience 78, 361–371 (1997). (10.1016/S0306-4522(96)00525-8) / Neuroscience by RA Hall (1997)
  11. Hall, R. A. & Soderling, T. R. Differential surface expression and phosphorylation of the N-methyl-D-aspartate receptor subunits NR1 and NR2 in cultured hippocampal neurons. J. Biol. Chem. 272, 4135–4140 (1997). (10.1074/jbc.272.7.4135) / J. Biol. Chem. by RA Hall (1997)
  12. Nayak, A. S., Moore, C. I. & Browning, M. D. Ca2+/calmodulin-dependent protein kinase II phosphorylation of the presynaptic protein synapsin I is persistently increased during long-term potentiation. Proc. Natl. Acad. Sci. USA 93, 15451–15456 (1996). (10.1073/pnas.93.26.15451) / Proc. Natl. Acad. Sci. USA by AS Nayak (1996)
  13. Nayak, A., Zastrow, D. J., Lickteig, R., Zahniser, N. R. & Browning, M. D. Maintenance of late-phase LTP is accompanied by PKA-dependent increase in AMPA receptor synthesis. Nature 394, 680–683 (1998). (10.1038/29305) / Nature by A Nayak (1998)
  14. Pickard, L., Noel, J., Henley, J. M., Collingridge, G. L. & Molnar, E. Developmental changes in synaptic AMPA and NMDA receptor distribution and AMPA receptor subunit composition in living hippocampal neurons. J. Neurosci. 20, 7922–7931 (2000). (10.1523/JNEUROSCI.20-21-07922.2000) / J. Neurosci. by L Pickard (2000)
  15. Mammen, A. L., Huganir, R. L. & O' Brien, R. J. Redistribution and stabilization of cell surface glutamate receptors during synapse formation. J. Neurosci. 17, 7351–7358 (1997). (10.1523/JNEUROSCI.17-19-07351.1997) / J. Neurosci. by AL Mammen (1997)
  16. Dunah, A. W. & Standaert, D. G. Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane. J. Neurosci. 21, 5546–5558 (2001). (10.1523/JNEUROSCI.21-15-05546.2001) / J. Neurosci. by AW Dunah (2001)
  17. David, V., Hochstenbach, F., Rajagopalan, S. & Brenner, M. B. Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin). J. Biol. Chem. 268, 9585–9592 (1993). (10.1016/S0021-9258(18)98391-2) / J. Biol. Chem. by V David (1993)
  18. Miyatani, S. et al. Neural cadherin: role in selective cell–cell adhesion. Science 245, 631–635 (1989). (10.1126/science.2762814) / Science by S Miyatani (1989)
  19. Bashir, Z. I., Alford, S., Davies, S. N., Randall, A. D. & Collingridge, G. L. Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus. Nature 349, 156–158 (1991). (10.1038/349156a0) / Nature by ZI Bashir (1991)
  20. Aniksztejn, L. & Ben-Ari, Y. Expression of LTP by AMPA and/or NMDA receptors is determined by the extent of NMDA receptors activation during the tetanus. J. Neurophysiol. 74, 2349–2357 (1995). (10.1152/jn.1995.74.6.2349) / J. Neurophysiol. by L Aniksztejn (1995)
  21. Kauer, J. A., Malenka, R. C. & Nicoll, R. A. A persistent postsynaptic modification mediates long-term potentiation in the hippocampus. Neuron 1, 911–917 (1988). (10.1016/0896-6273(88)90148-1) / Neuron by JA Kauer (1988)
  22. Lau, L. F. & Huganir, R. L. Differential tyrosine phosphorylation of N-methyl-D-aspartate receptor subunits. J. Biol. Chem. 270, 20036–20041 (1995). (10.1074/jbc.270.34.20036) / J. Biol. Chem. by LF Lau (1995)
  23. Grosshans, D. R. & Browning, M. D. Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor. J. Neurochem. 76, 737–744 (2001). (10.1046/j.1471-4159.2001.00034.x) / J. Neurochem. by DR Grosshans (2001)
  24. Rosenblum, K., Dudai, Y. & Richter-Levin, G. Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo. Proc. Natl. Acad. Sci. USA 93, 10457–10460 (1996). (10.1073/pnas.93.19.10457) / Proc. Natl. Acad. Sci. USA by K Rosenblum (1996)
  25. Rosenblum, K., Berman, D. E., Hazvi, S., Lamprecht, R. & Dudai, Y. NMDA receptor and the tyrosine phosphorylation of its 2B subunit in taste learning in the rat insular cortex. J. Neurosci. 17, 5129–5135 (1997). (10.1523/JNEUROSCI.17-13-05129.1997) / J. Neurosci. by K Rosenblum (1997)
  26. Parfitt, K. D. & Madison, D. V. Phorbol esters enhance synaptic transmission by a presynaptic, calcium-dependent mechanism in rat hippocampus. J. Physiol. (Lond.) 471, 245–268 (1993). (10.1113/jphysiol.1993.sp019900) / J. Physiol. (Lond.) by KD Parfitt (1993)
  27. Waters, J. & Smith, S. J. Phorbol esters potentiate evoked and spontaneous release by different presynaptic mechanisms. J. Neurosci. 20, 7863–7870 (2000). (10.1523/JNEUROSCI.20-21-07863.2000) / J. Neurosci. by J Waters (2000)
  28. Chazot, P. L. & Stephenson, F. A. Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor. J. Neurochem. 68, 507–516 (1997). (10.1046/j.1471-4159.1997.68020507.x) / J. Neurochem. by PL Chazot (1997)
  29. Okabe, S., Miwa, A. & Okado, H. Alternative splicing of the C-terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit. J. Neurosci. 19, 7781–7792 (1999). (10.1523/JNEUROSCI.19-18-07781.1999) / J. Neurosci. by S Okabe (1999)
  30. Lu, W. et al. Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons. Neuron 29, 243–254 (2001). (10.1016/S0896-6273(01)00194-5) / Neuron by W Lu (2001)
  31. Heynen, A. J., Quinlan, E. M., Bae, D. C. & Bear, M. F. Bidirectional, activity-dependent regulation of glutamate receptors in the adult hippocampus in vivo. Neuron 28, 527–536 (2000). (10.1016/S0896-6273(00)00130-6) / Neuron by AJ Heynen (2000)
  32. Shi, S., Hayashi, Y., Esteban, J. A. & Malinow, R. Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell 105, 331–343 (2001). (10.1016/S0092-8674(01)00321-X) / Cell by S Shi (2001)
  33. Standley, S., Roche, K. W., McCallum, J., Sans, N. & Wenthold, R. J. PDZ domain suppression of an ER retention signal in NMDA receptor NR1 splice variants. Neuron 28, 887–898 (2000). (10.1016/S0896-6273(00)00161-6) / Neuron by S Standley (2000)
  34. Vissel, B., Krupp, J. J., Heinemann, S. F. & Westbrook, G. L. A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux. Nat. Neurosci. 4, 587–596 (2001). (10.1038/88404) / Nat. Neurosci. by B Vissel (2001)
  35. Roche, K. W. et al. Molecular determinants of NMDA receptor internalization. Nat. Neurosci. 4, 794–802 (2001). (10.1038/90498) / Nat. Neurosci. by KW Roche (2001)
  36. Lu, Y. M., Roder, J. C., Davidow, J. & Salter, M. W. Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. Science 279, 1363–1367 (1998). (10.1126/science.279.5355.1363) / Science by YM Lu (1998)
  37. Salter, M. W. Src, N-methyl-D-aspartate (NMDA) receptors, and synaptic plasticity. Biochem. Pharmacol. 56, 789–798 (1998). (10.1016/S0006-2952(98)00124-5) / Biochem. Pharmacol. by MW Salter (1998)
  38. Gardoni, F. et al. Hippocampal synaptic plasticity involves competition between Ca2+/calmodulin-dependent protein kinase II and postsynaptic density 95 for binding to the NR2A subunit of the NMDA receptor. J. Neurosci. 21, 1501–1509 (2001). (10.1523/JNEUROSCI.21-05-01501.2001) / J. Neurosci. by F Gardoni (2001)
  39. Benke, T. A., Lüthi, A., Isaac, J. T. & Collingridge, G. L. Modulation of AMPA receptor unitary conductance by synaptic activity. Nature 393, 793–797 (1998). (10.1038/31709) / Nature by TA Benke (1998)
  40. Derkach, V., Barria, A. & Soderling, T. R. Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors. Proc. Natl. Acad. Sci. USA 96, 3269–3274 (1999). (10.1073/pnas.96.6.3269) / Proc. Natl. Acad. Sci. USA by V Derkach (1999)
  41. Lee, H. K., Barbarosie, M., Kameyama, K., Bear, M. F. & Huganir, R. L. Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature 405, 955–959 (2000). (10.1038/35016089) / Nature by HK Lee (2000)
  42. Snell, L. D. et al. Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion. Brain Res. Mol. Brain Res. 40, 71–78 (1996). (10.1016/0169-328X(96)00038-1) / Brain Res. Mol. Brain Res. by LD Snell (1996)
  43. Stone, L. M., Browning, M. D. & Finger, T. E. Differential distribution of the synapsins in the rat olfactory bulb. J. Neurosci. 14, 301–309 (1994). (10.1523/JNEUROSCI.14-01-00301.1994) / J. Neurosci. by LM Stone (1994)
  44. Wenthold, R. J., Yokotani, N., Doi, K. & Wada, K. Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. Evidence for a hetero-oligomeric structure in rat brain. J. Biol. Chem. 267, 501–507 (1992). (10.1016/S0021-9258(18)48523-7) / J. Biol. Chem. by RJ Wenthold (1992)
  45. Petralia, R. S., Wang, Y. X., Mayat, E. & Wenthold, R. J. Glutamate receptor subunit 2-selective antibody shows a differential distribution of calcium-impermeable AMPA receptors among populations of neurons. J. Comp. Neurol. 385, 456–476 (1997). (10.1002/(SICI)1096-9861(19970901)385:3<456::AID-CNE9>3.0.CO;2-2) / J. Comp. Neurol. by RS Petralia (1997)
  46. Porter, R. M. et al. Monoclonal antibodies to cytoskeletal proteins: an immunohistochemical investigation of human colon cancer. J. Pathol. 170, 435–440 (1993). (10.1002/path.1711700406) / J. Pathol. by RM Porter (1993)
  47. Siegel, S. J. et al. Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus. Proc. Natl. Acad. Sci. USA 91, 564–568 (1994). (10.1073/pnas.91.2.564) / Proc. Natl. Acad. Sci. USA by SJ Siegel (1994)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:34 a.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 8:02 p.m.)
Indexed 2 days, 19 hours ago (Sept. 3, 2025, 6:17 a.m.)
Issued 23 years, 8 months ago (Dec. 10, 2001)
Published 23 years, 8 months ago (Dec. 10, 2001)
Published Online 23 years, 8 months ago (Dec. 10, 2001)
Published Print 23 years, 8 months ago (Jan. 1, 2002)
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@article{Grosshans_2001, title={LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1}, volume={5}, ISSN={1546-1726}, url={http://dx.doi.org/10.1038/nn779}, DOI={10.1038/nn779}, number={1}, journal={Nature Neuroscience}, publisher={Springer Science and Business Media LLC}, author={Grosshans, D. R. and Clayton, D. A. and Coultrap, S. J. and Browning, M. D.}, year={2001}, month=dec, pages={27–33} }